Summary for 2ZMF
| Entry DOI | 10.2210/pdb2zmf/pdb |
| Descriptor | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total) |
| Functional Keywords | gaf domain, phosphodiesterase, camp, cgmp, cgmp-binding, hydrolase, nucleotide-binding, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q9Y233 |
| Total number of polymer chains | 2 |
| Total formula weight | 43611.88 |
| Authors | Handa, N.,Kishishita, S.,Mizohata, E.,Omori, K.,Kotera, J.,Terada, T.,Shirouzu, M.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-04-17, release date: 2008-04-29, Last modification date: 2011-07-13) |
| Primary citation | Handa, N.,Mizohata, E.,Kishishita, S.,Toyama, M.,Morita, S.,Uchikubo-Kamo, T.,Akasaka, R.,Omori, K.,Kotera, J.,Terada, T.,Shirouzu, M.,Yokoyama, S. Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP J.Biol.Chem., 283:19657-19664, 2008 Cited by PubMed: 18477562DOI: 10.1074/jbc.M800595200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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