Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2ZMF

Crystal structure of the C-terminal GAF domain of human phosphodiesterase 10A

Replaces:  2E4S
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Apolymer18921476.72UniProt (Q9Y233)
Pfam (PF00233)
In PDB
Homo sapiens (human)
2A, BADENOSINE-3',5'-CYCLIC-MONOPHOSPHATEnon-polymer329.22Chemie (CMP)
3waterwater18.0168Chemie (HOH)
Sequence modifications
A, B: 246 - 427 (UniProt: Q9Y233)
PDBExternal DatabaseDetails
Gly 239-EXPRESSION TAG
Ser 240-EXPRESSION TAG
Ser 241-EXPRESSION TAG
Gly 242-EXPRESSION TAG
Ser 243-EXPRESSION TAG
Ser 244-EXPRESSION TAG
Gly 245-EXPRESSION TAG
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42953.5
Non-Polymers*Number of molecules2
Total formula weight658.4
All*Total formula weight43611.9
*Water molecules are not included.

224201

PDB entries from 2024-08-28

PDB statisticsPDBj update infoContact PDBjnumon