4IYD
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7NP4
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![BU of 7np4 by Molmil](/molmil-images/mine/7np4) | cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 著者 | Giese, H, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | 登録日 | 2021-02-26 | 公開日 | 2021-08-11 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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7NP3
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![BU of 7np3 by Molmil](/molmil-images/mine/7np3) | cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture | 分子名称: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | 著者 | Giese, H.M, Chaves-Sanjuan, A, Saponaro, A, Clarke, O, Bolognesi, M, Mancia, F, Hendrickson, W.A, Thiel, G, Santoro, B, Moroni, A. | 登録日 | 2021-02-26 | 公開日 | 2021-08-11 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Gating movements and ion permeation in HCN4 pacemaker channels. Mol.Cell, 81, 2021
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8IJV
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![BU of 8ijv by Molmil](/molmil-images/mine/8ijv) | Cryo-EM structure of the gastric proton pump with bound DQ-02 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[[5-chloranyl-2-(4-chlorophenyl)phenyl]methoxy]-N-methyl-but-2-yn-1-amine, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.1 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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8JMN
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![BU of 8jmn by Molmil](/molmil-images/mine/8jmn) | Cryo-EM structure of the gastric proton pump with bound DQ-21 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[[2-[(4-chlorophenyl)methoxy]phenyl]methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-06-05 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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8IJX
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![BU of 8ijx by Molmil](/molmil-images/mine/8ijx) | Cryo-EM structure of the gastric proton pump with bound DQ-18 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[4-[(5-chloranyl-2-phenylmethoxy-phenyl)methoxy]phenyl]-N-methyl-methanamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.08 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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8IJW
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![BU of 8ijw by Molmil](/molmil-images/mine/8ijw) | Cryo-EM structure of the gastric proton pump with bound DQ-06 | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | 著者 | Abe, K, Yokoshima, S, Yoshimori, A. | 登録日 | 2023-02-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Deep learning driven de novo drug design based on gastric proton pump structures. Commun Biol, 6, 2023
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5O5X
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![BU of 5o5x by Molmil](/molmil-images/mine/5o5x) | Crystal structure of Thermococcus litoralis ADP-dependent glucokinase (GK) | 分子名称: | ADP-dependent glucokinase,ADP-dependent glucokinase,ADP-dependent glucokinase, GLYCEROL, SULFATE ION | 著者 | Herrera-Morande, A, Castro-Fernandez, V, Merino, F, Ramirez-Sarmiento, C.A, Fernandez, F.J, Guixe, V, Vega, M.C. | 登録日 | 2017-06-02 | 公開日 | 2018-10-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.148 Å) | 主引用文献 | Protein topology determines substrate-binding mechanism in homologous enzymes. Biochim Biophys Acta Gen Subj, 1862, 2018
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5O5Z
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![BU of 5o5z by Molmil](/molmil-images/mine/5o5z) | CRYSTAL STRUCTURE OF THERMOCOCCUS LITORALIS ADP-DEPENDENT GLUCOKINASE (GK) | 分子名称: | 5'-O-[(R)-HYDROXY(THIOPHOSPHONOOXY)PHOSPHORYL]ADENOSINE, ADP-dependent glucokinase,ADP-dependent glucokinase,ADP-dependent glucokinase, GLYCEROL, ... | 著者 | Herrera-Morande, A, Castro-Fernandez, V, Merino, F, Ramirez-Sarmiento, C.A, Fernandez, F.J, Guixe, V, Vega, M.C. | 登録日 | 2017-06-02 | 公開日 | 2018-10-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.441 Å) | 主引用文献 | Protein topology determines substrate-binding mechanism in homologous enzymes. Biochim Biophys Acta Gen Subj, 1862, 2018
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5O5Y
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![BU of 5o5y by Molmil](/molmil-images/mine/5o5y) | Crystal structure of Thermococcus litoralis ADP-dependent glucokinase (GK) | 分子名称: | ADP-dependent glucokinase,ADP-dependent glucokinase,ADP-dependent glucokinase, GLYCEROL, TRIETHYLENE GLYCOL, ... | 著者 | Herrera-Morande, A, Castro-Fernandez, V, Merino, F, Ramirez-Sarmiento, C.A, Fernandez, F.J, Guixe, V, Vega, M.C. | 登録日 | 2017-06-02 | 公開日 | 2018-10-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.915 Å) | 主引用文献 | Protein topology determines substrate-binding mechanism in homologous enzymes. Biochim Biophys Acta Gen Subj, 1862, 2018
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5NWK
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![BU of 5nwk by Molmil](/molmil-images/mine/5nwk) | 14-3-3c in complex with CPP and fusicoccin | 分子名称: | 14-3-3 c-1 protein, FUSICOCCIN, PHOSPHOSERINE, ... | 著者 | Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. | 登録日 | 2017-05-06 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
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5NWI
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![BU of 5nwi by Molmil](/molmil-images/mine/5nwi) | 14-3-3c in complex with CPP | 分子名称: | 14-3-3 c-1 protein, ACETATE ION, Potassium channel KAT1 | 著者 | Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. | 登録日 | 2017-05-06 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
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5NWJ
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![BU of 5nwj by Molmil](/molmil-images/mine/5nwj) | 14-3-3c in complex with CPP7 | 分子名称: | 14-3-3-like protein C, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Saponaro, A, Porro, A, Chaves-Sanjuan, A, Nardini, M, Thiel, G, Moroni, A. | 登録日 | 2017-05-06 | 公開日 | 2017-11-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Fusicoccin Activates KAT1 Channels by Stabilizing Their Interaction with 14-3-3 Proteins. Plant Cell, 29, 2017
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5AIJ
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![BU of 5aij by Molmil](/molmil-images/mine/5aij) | P. aeruginosa SdsA hexagonal polymorph | 分子名称: | ALKYL SULFATASE, GLYCEROL, ZINC ION | 著者 | De la Mora, E, Flores-Hernandez, E, Jakoncic, J, Stojanoff, V, Sanchez-Puig, N, Moreno, A. | 登録日 | 2015-02-13 | 公開日 | 2015-10-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Sdsa Polymorph Isolation and Improvement of Their Crystal Quality Using Nonconventional Crystallization Techniques J.Appl.Crystallogr., 48, 2015
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5A23
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![BU of 5a23 by Molmil](/molmil-images/mine/5a23) | SdsA sulfatase triclinic form | 分子名称: | SDS HYDROLASE SDSA1, ZINC ION | 著者 | De la Mora, E, Flores-Hernandez, E, Jakoncik, J, Stojanoff, V, Sanchez-Puig, N, Moreno, A. | 登録日 | 2015-05-11 | 公開日 | 2015-10-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Sdsa Polymorph Isolation and Improvement of Their Crystal Quality Using Nonconventional Crystallization Techniques J.Appl.Crystallogr., 48, 2015
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5AJL
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![BU of 5ajl by Molmil](/molmil-images/mine/5ajl) | Sdsa sulfatase tetragonal | 分子名称: | ALKYL SULFATASE, ZINC ION | 著者 | De la Mora, E, Flores-Hernandez, E, Jakoncic, J, Stojanoff, V, Sanchez-Puig, N, Moreno, A. | 登録日 | 2015-02-25 | 公開日 | 2015-10-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Sdsa Polymorph Isolation and Improvement of Their Crystal Quality Using Nonconventional Crystallization Techniques J.Appl.Crystallogr., 48, 2015
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6S6Q
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![BU of 6s6q by Molmil](/molmil-images/mine/6s6q) | Crystal structure of the LRR ectodomain of the plant membrane receptor kinase GASSHO1/SCHENGEN3 from Arabidopsis thaliana in complex with CASPARIAN STRIP INTEGRITY FACTOR 2. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LRR receptor-like serine/threonine-protein kinase GSO1, ... | 著者 | Okuda, S, Moretti, A, Hothorn, M. | 登録日 | 2019-07-03 | 公開日 | 2020-01-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2. Proc.Natl.Acad.Sci.USA, 117, 2020
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4KL1
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![BU of 4kl1 by Molmil](/molmil-images/mine/4kl1) | HCN4 CNBD in complex with cGMP | 分子名称: | ACETATE ION, CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, ... | 著者 | Lolicato, M, Arrigoni, C, Zucca, S, Nardini, M, Bucchi, A, Schroeder, I, Simmons, K, Bolognesi, M, DiFrancesco, D, Schwede, F, Fishwick, C.W.G, Johnson, A.P.K, Thiel, G, Moroni, A. | 登録日 | 2013-05-07 | 公開日 | 2014-04-30 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nat.Chem.Biol., 10, 2014
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1OLL
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![BU of 1oll by Molmil](/molmil-images/mine/1oll) | Extracellular region of the human receptor NKp46 | 分子名称: | 1,2-ETHANEDIOL, NK RECEPTOR | 著者 | Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Pesce, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D. | 登録日 | 2003-08-07 | 公開日 | 2003-09-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structure of the Human Nk Cell Triggering Receptor Nkp46 Ectodomain Biochem.Biophys.Res.Commun., 309, 2003
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6PAJ
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1HKF
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![BU of 1hkf by Molmil](/molmil-images/mine/1hkf) | The three dimensional structure of NK cell receptor Nkp44, a triggering partner in natural cytotoxicity | 分子名称: | NK CELL ACTIVATING RECEPTOR | 著者 | Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D. | 登録日 | 2003-03-10 | 公開日 | 2003-06-11 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Three-Dimensional Structure of the Human Nk Cell Receptor Nkp44, a Triggering Partner in Natural Cytotoxicity Structure, 11, 2003
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7L07
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![BU of 7l07 by Molmil](/molmil-images/mine/7l07) | Last common ancestor of HMPPK and PLK/HMPPK vitamin kinases | 分子名称: | ALUMINUM FLUORIDE, Ancestral Protein AncC | 著者 | Gonzalez-Ordenes, F, Maturana, P, Herrera-Morande, A, Araya, G, Arizabalos, S, Castro-Fernandez, V. | 登録日 | 2020-12-11 | 公開日 | 2021-02-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure and molecular dynamics simulations of a promiscuous ancestor reveal residues and an epistatic interaction involved in substrate binding and catalysis in the ATP-dependent vitamin kinase family members. Protein Sci., 30, 2021
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6HDC
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![BU of 6hdc by Molmil](/molmil-images/mine/6hdc) | Crystal structure of the potassium channel MtTMEM175 T38A variant in complex with a Nanobody-MBP fusion protein | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Nanobody,Maltose/maltodextrin-binding periplasmic protein,Maltose/maltodextrin-binding periplasmic protein, POTASSIUM ION, ... | 著者 | Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S. | 登録日 | 2018-08-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis for ion selectivity in TMEM175 K+channels. Elife, 9, 2020
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6HDB
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![BU of 6hdb by Molmil](/molmil-images/mine/6hdb) | Crystal structure of the potassium channel MtTMEM175 with zinc | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Nanobody,Maltose/maltodextrin-binding periplasmic protein, POTASSIUM ION, ... | 著者 | Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S. | 登録日 | 2018-08-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis for ion selectivity in TMEM175 K+channels. Elife, 9, 2020
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6HD9
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![BU of 6hd9 by Molmil](/molmil-images/mine/6hd9) | Crystal structure of the potassium channel MtTMEM175 with rubidium | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Nanobody,Maltose/maltodextrin-binding periplasmic protein, RUBIDIUM ION, ... | 著者 | Brunner, J.D, Jakob, R.P, Schulze, T, Neldner, Y, Moroni, A, Thiel, G, Maier, T, Schenck, S. | 登録日 | 2018-08-17 | 公開日 | 2019-08-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Structural basis for ion selectivity in TMEM175 K+channels. Elife, 9, 2020
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