3CDV
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3C80
| T4 Lysozyme mutant R96Y at room temperature | Descriptor: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | Authors: | Mooers, B.H.M. | Deposit date: | 2008-02-08 | Release date: | 2009-02-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme. Protein Sci., 18, 2009
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3F8V
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3FA0
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3FAD
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3FI5
| Crystal Structure of T4 Lysozyme Mutant R96W | Descriptor: | CHLORIDE ION, ISOPROPYL ALCOHOL, Lysozyme, ... | Authors: | Mooers, B.H.M, Matthews, B.W. | Deposit date: | 2008-12-11 | Release date: | 2009-02-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Contributions of all 20 amino acids at site 96 to the stability and structure of T4 lysozyme. Protein Sci., 18, 2009
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3F9L
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339D
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338D
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340D
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343D
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345D
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341D
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342D
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346D
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337D
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8G2K
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4DGR
| Influenza Subtype 9 Neuraminidase Benzoic Acid Inhibitor Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[2,2-bis(hydroxymethyl)-5-oxopyrrolidin-1-yl]-3-[(dipropylamino)methyl]benzoic acid, CALCIUM ION, ... | Authors: | Venkatramani, L, Johnson, E, Kolavi, G, Air, G.M, Brouillette, W, Mooers, B.H.M. | Deposit date: | 2012-01-26 | Release date: | 2012-05-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.551 Å) | Cite: | Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking sub-site C6. Bmc Struct.Biol., 12, 2012
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4GG2
| The crystal structure of glutamate-bound human gamma-glutamyltranspeptidase 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ... | Authors: | West, M.B, Chen, Y, Wickham, S, Heroux, A, Cahill, K, Hanigan, M.H, Mooers, B.H.M. | Deposit date: | 2012-08-04 | Release date: | 2013-09-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme. J.Biol.Chem., 288, 2013
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4GDX
| Crystal Structure of Human Gamma-Glutamyl Transpeptidase--Glutamate complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLUTAMIC ACID, ... | Authors: | West, M.B, Chen, Y, Wickham, S, Heroux, A, Cahill, K, Hanigan, M.H, Mooers, B.H.M. | Deposit date: | 2012-08-01 | Release date: | 2013-09-25 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Novel Insights into Eukaryotic gamma-Glutamyltranspeptidase 1 from the Crystal Structure of the Glutamate-bound Human Enzyme. J.Biol.Chem., 288, 2013
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7JU5
| Structure of RET protein tyrosine kinase in complex with pralsetinib | Descriptor: | FORMIC ACID, Pralsetinib, Proto-oncogene tyrosine-protein kinase receptor Ret | Authors: | Terzyan, S.S, Shen, T, Wu, J, Mooers, B.H.M. | Deposit date: | 2020-08-19 | Release date: | 2020-11-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations. Ann Oncol, 32, 2021
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7JU6
| Structure of RET protein tyrosine kinase in complex with selpercatinib | Descriptor: | FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret, Selpercatinib | Authors: | Terzyan, S.S, Shen, T, Wu, J, Mooers, B.H.M. | Deposit date: | 2020-08-19 | Release date: | 2020-11-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structural basis of acquired resistance to selpercatinib and pralsetinib mediated by non-gatekeeper RET mutations. Ann Oncol, 32, 2021
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1FHZ
| PSORALEN CROSS-LINKED D(CCGGTACCGG) FORMS HOLLIDAY JUNCTION | Descriptor: | 4'-HYDROXYMETHYL-4,5',8-TRIMETHYLPSORALEN, DNA (5'-D(*CP*CP*GP*GP*TP*AP*CP*CP*GP*G)-3') | Authors: | Eichman, B.F, Mooers, B.H.M, Alberti, M, Hearst, J.E, Ho, P.S. | Deposit date: | 2000-08-02 | Release date: | 2001-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions. J.Mol.Biol., 308, 2001
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1FHY
| PSORALEN CROSS-LINKED D(CCGCTAGCGG) FORMS HOLLIDAY JUNCTION | Descriptor: | 4'-HYDROXYMETHYL-4,5',8-TRIMETHYLPSORALEN, CALCIUM ION, DNA (5'-D(*CP*CP*GP*CP*TP*AP*GP*CP*GP*G)-3') | Authors: | Eichman, B.F, Mooers, B.H.M, Alberti, M, Hearst, J.E, Ho, P.S. | Deposit date: | 2000-08-02 | Release date: | 2001-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structures of psoralen cross-linked DNAs: drug-dependent formation of Holliday junctions. J.Mol.Biol., 308, 2001
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1DCV
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