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PDB: 90 件
6OVZ
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Crystal structure of the New Delhi metallo-beta-lactamase-1 adduct with a lysine-targeted affinity label
分子名称: Beta-lactamase, CALCIUM ION, ZINC ION, ...
著者Monzingo, A.F, Fast, W, Thomas, P.W.
登録日2019-05-08
公開日2019-06-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.017 Å)
主引用文献A Lysine-Targeted Affinity Label for Serine-beta-Lactamase Also Covalently Modifies New Delhi Metallo-beta-lactamase-1 (NDM-1).
Biochemistry, 58, 2019
6DGE
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Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with N5-(1-imino-2-chloroethyl)-L-lysine
分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~6~-[(1E)-2-chloroethanimidoyl]-L-lysine
著者Monzingo, A.F, Burstein-Teitelbaum, G, Er, J.A.V, Tuley, A, Fast, W.
登録日2018-05-17
公開日2018-07-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Dissection, Optimization, and Structural Analysis of a Covalent Irreversible DDAH1 Inhibitor.
Biochemistry, 57, 2018
1TMN
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Binding of n-carboxymethyl dipeptide inhibitors to thermolysin determined by x-ray crystallography. a novel class of transition-state analogues for zinc peptidases
分子名称: CALCIUM ION, N-[(1R)-1-carboxy-3-phenylpropyl]-L-leucyl-L-tryptophan, THERMOLYSIN, ...
著者Monzingo, A.F, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases
Biochemistry, 23, 1984
2IDR
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Crystal structure of translation initiation factor EIF4E from wheat
分子名称: Eukaryotic translation initiation factor 4E-1
著者Monzingo, A.F, Sadow, J, Dhaliwal, S, Lyon, A, Hoffman, D.W, Robertus, J.D, Browning, K.S.
登録日2006-09-15
公開日2007-06-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
2IDV
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Crystal structure of wheat C113S mutant EIF4E bound TO 7-methyl-GDP
分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E-1
著者Monzingo, A.F, Dutt-Chaudhuri, A, Sadow, J, Dhaliwal, S, Hoffman, D.W, Robertus, J.D, Browning, K.S.
登録日2006-09-15
公開日2007-06-12
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of eukaryotic translation initiation factor-4E from wheat reveals a novel disulfide bond.
Plant Physiol., 143, 2007
1EE9
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CRYSTAL STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH NAD
分子名称: 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Monzingo, A.F, Breksa, A, Ernst, S, Appling, D.R, Robertus, J.D.
登録日2000-01-31
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci., 9, 2000
1EDZ
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STRUCTURE OF THE NAD-DEPENDENT 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE
分子名称: 5,10-METHYLENETETRAHYDROFOLATE DEHYDROGENASE
著者Monzingo, A.F, Breksa, A, Ernst, S, Appling, D.R, Robertus, J.D.
登録日2000-01-28
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The X-ray structure of the NAD-dependent 5,10-methylenetetrahydrofolate dehydrogenase from Saccharomyces cerevisiae.
Protein Sci., 9, 2000
3I2E
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Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1)
分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1
著者Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Robertus, J.D, Fast, W.
登録日2009-06-29
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Biochemistry, 48, 2009
3I4A
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Crystal structure of dimethylarginine dimethylaminohydrolase-1 (DDAH-1) in complex with N5-(1-iminopropyl)-L-ornithine
分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N5-(1-iminopropyl)-L-ornithine
著者Monzingo, A.F, Wang, Y, Hu, S, Schaller, T.H, Fast, W, Robertus, J.D.
登録日2009-07-01
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.
Biochemistry, 48, 2009
2NS6
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Crystal Structure of the Minimal Relaxase Domain of MobA from Plasmid R1162
分子名称: MANGANESE (II) ION, Mobilization protein A
著者Monzingo, A.F, Ozburn, A, Xia, S, Meyer, R.J, Robertus, J.D.
登録日2006-11-03
公開日2007-02-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Structure of the Minimal Relaxase Domain of MobA at 2.1 A Resolution.
J.Mol.Biol., 366, 2007
1PAF
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THE 2.5 ANGSTROMS STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN
分子名称: POKEWEED ANTIVIRAL PROTEIN
著者Monzingo, A.F, Collins, E.J, Ernst, S.R, Irvin, J.D, Robertus, J.D.
登録日1992-10-19
公開日1994-01-31
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The 2.5 A structure of pokeweed antiviral protein.
J.Mol.Biol., 233, 1993
1PAG
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THE 2.5 ANGSTROMS STRUCTURE OF POKEWEED ANTIVIRAL PROTEIN
分子名称: FORMYCIN-5'-MONOPHOSPHATE, POKEWEED ANTIVIRAL PROTEIN
著者Monzingo, A.F, Collins, E.J, Ernst, S.R, Irvin, J.D, Robertus, J.D.
登録日1992-10-19
公開日1994-01-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The 2.5 A structure of pokeweed antiviral protein.
J.Mol.Biol., 233, 1993
3BPB
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BU of 3bpb by Molmil
Crystal structure of the dimethylarginine dimethylaminohydrolase H162G adduct with S-methyl-L-thiocitrulline
分子名称: N~5~-[(E)-imino(methylsulfanyl)methyl]-L-ornithine, dimethylarginine dimethylaminohydrolase
著者Monzingo, A.F, Linsky, T.W, Stone, E.M, Fast, W, Robertus, J.D.
登録日2007-12-18
公開日2008-06-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Promiscuous partitioning of a covalent intermediate common in the pentein superfamily.
Chem.Biol., 15, 2008
3ETB
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BU of 3etb by Molmil
Crystal structure of the engineered neutralizing antibody M18 complexed with anthrax protective antigen domain 4
分子名称: Anthrax Protective Antigen, Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-07
公開日2009-04-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ESU
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Crystal structure of anthrax-neutralizing single-chain antibody 14b7
分子名称: Antibody 14b7* light chain and antibody 14b7* heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Maynard, J.A, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-06
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
3ESV
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Crystal structure of the engineered neutralizing antibody M18
分子名称: Antibody M18 light chain and antibody M18 heavy chain linked with a synthetic (GGGGS)4 linker
著者Monzingo, A.F, Leysath, C.E, Barnett, J, Iverson, B.L, Georgiou, G, Robertus, J.D.
登録日2008-10-06
公開日2009-04-28
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the engineered neutralizing antibody m18 complexed to domain 4 of the anthrax protective antigen.
J.Mol.Biol., 387, 2009
1Q5X
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Structure of OF RRAA (MENG), a protein inhibitor of RNA processing
分子名称: REGULATOR OF RNASE E ACTIVITY A
著者Monzingo, A.F, Gao, J, Qiu, J, Georgiou, G, Robertus, J.D.
登録日2003-08-11
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The X-ray Structure of Escherichia coli RraA (MenG), A Protein Inhibitor of RNA Processing.
J.Mol.Biol., 332, 2003
3RTJ
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BU of 3rtj by Molmil
Crystal structure of ricin bound with dinucleotide ApG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (5'-R(*AP*G)-3'), Ricin A chain, ...
著者Monzingo, A.F, Robertus, J.D.
登録日2011-05-03
公開日2011-08-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray analysis of substrate analogs in the ricin A-chain active site.
J.Mol.Biol., 227, 1992
3RHY
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Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine
分子名称: (4-chloropyridin-2-yl)methanol, N(G),N(G)-dimethylarginine dimethylaminohydrolase
著者Monzingo, A.F, Johnson, C.M, Ke, Z, Yoon, D.-W, Linsky, T.W, Guo, H, Fast, W, Robertus, J.D.
登録日2011-04-12
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献On the mechanism of dimethylarginine dimethylaminohydrolase inactivation by 4-halopyridines.
J.Am.Chem.Soc., 133, 2011
3RTI
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Crystal structure of ricin bound with formycin monophosphate
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FORMYCIN-5'-MONOPHOSPHATE, Ricin, ...
著者Monzingo, A.F, Robertus, J.D.
登録日2011-05-03
公開日2011-08-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray analysis of substrate analogs in the ricin A-chain active site.
J.Mol.Biol., 227, 1992
3P8P
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Crystal Structure of Human Dimethylarginine Dimethylaminohydrolase-1 (DDAH-1) variant C274S bound with N5-(1-iminopentyl)-L-ornithine
分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, N~5~-[(1E)-pentanimidoyl]-L-ornithine
著者Monzingo, A.F, Lluis, M, Wang, Y, Fast, W, Robertus, J.D.
登録日2010-10-14
公開日2010-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of C-Alkyl Amidines as Bioavailable Covalent Reversible Inhibitors of Human DDAH-1.
Chemmedchem, 6, 2011
2TMN
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CRYSTALLOGRAPHIC STRUCTURAL ANALYSIS OF PHOSPHORAMIDATES AS INHIBITORS AND TRANSITION-STATE ANALOGS OF THERMOLYSIN
分子名称: CALCIUM ION, N~2~-phosphono-L-leucinamide, Thermolysin, ...
著者Tronrud, D.E, Monzingo, A.F, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin.
Eur.J.Biochem., 157, 1986
4TMN
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SLOW-AND FAST-BINDING INHIBITORS OF THERMOLYSIN DISPLAY DIFFERENT MODES OF BINDING. CRYSTALLOGRAPHIC ANALYSIS OF EXTENDED PHOSPHONAMIDATE TRANSITION-STATE ANALOGUES
分子名称: CALCIUM ION, N-[(S)-[(1R)-1-{[(benzyloxy)carbonyl]amino}-2-phenylethyl](hydroxy)phosphoryl]-L-leucyl-L-alanine, THERMOLYSIN, ...
著者Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
5TMN
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Slow-and fast-binding inhibitors of thermolysin display different modes of binding. crystallographic analysis of extended phosphonamidate transition-state analogues
分子名称: CALCIUM ION, N-[(S)-({[(benzyloxy)carbonyl]amino}methyl)(hydroxy)phosphoryl]-L-leucyl-L-leucine, THERMOLYSIN, ...
著者Holden, H.M, Tronrud, D.E, Monzingo, A.F, Weaver, L.H, Matthews, B.W.
登録日1987-06-29
公開日1989-01-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues.
Biochemistry, 26, 1987
2BAA
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THE REFINED CRYSTAL STRUCTURE OF AN ENDOCHITINASE FROM HORDEUM VULGARE L. SEEDS TO 1.8 ANGSTROMS RESOLUTION
分子名称: ENDOCHITINASE (26 KD)
著者Hart, P.J, Pfluger, H.D, Monzingo, A.F, Ready, M.P, Ernst, S.R, Hollis, T, Robertus, J.D.
登録日1995-01-26
公開日1996-01-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The refined crystal structure of an endochitinase from Hordeum vulgare L. seeds at 1.8 A resolution.
J.Mol.Biol., 248, 1995

 

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