3RHY
Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine
Summary for 3RHY
Entry DOI | 10.2210/pdb3rhy/pdb |
Related | 1H70 3BPB |
Descriptor | N(G),N(G)-dimethylarginine dimethylaminohydrolase, (4-chloropyridin-2-yl)methanol (3 entities in total) |
Functional Keywords | enzyme adduct, hydrolase |
Biological source | Pseudomonas aeruginosa |
Total number of polymer chains | 2 |
Total formula weight | 57300.18 |
Authors | Monzingo, A.F.,Johnson, C.M.,Ke, Z.,Yoon, D.-W.,Linsky, T.W.,Guo, H.,Fast, W.,Robertus, J.D. (deposition date: 2011-04-12, release date: 2011-06-15, Last modification date: 2023-09-13) |
Primary citation | Johnson, C.M.,Monzingo, A.F.,Ke, Z.,Yoon, D.W.,Linsky, T.W.,Guo, H.,Robertus, J.D.,Fast, W. On the mechanism of dimethylarginine dimethylaminohydrolase inactivation by 4-halopyridines. J.Am.Chem.Soc., 133:10951-10959, 2011 Cited by PubMed: 21630706DOI: 10.1021/ja2033684 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.18 Å) |
Structure validation
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