3I2E

Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1)

Summary for 3I2E

Entry DOI	10.2210/pdb3i2e/pdb
Descriptor	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (2 entities in total)
Functional Keywords	ddah, hydrolase, nitric oxide synthase regulator, metal-binding, zinc
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	67246.98
Authors	Monzingo, A.F.,Wang, Y.,Hu, S.,Schaller, T.H.,Robertus, J.D.,Fast, W. (deposition date: 2009-06-29, release date: 2009-08-25, Last modification date: 2023-09-06)
Primary citation	Wang, Y.,Monzingo, A.F.,Hu, S.,Schaller, T.H.,Robertus, J.D.,Fast, W. Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. Biochemistry, 48:8624-8635, 2009 Cited by PubMed: 19663506 DOI: 10.1021/bi9007098 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation