6OVZ
Crystal structure of the New Delhi metallo-beta-lactamase-1 adduct with a lysine-targeted affinity label
Summary for 6OVZ
Entry DOI | 10.2210/pdb6ovz/pdb |
Descriptor | Beta-lactamase, ZINC ION, CALCIUM ION, ... (7 entities in total) |
Functional Keywords | ndm-1, affinity-label, covalent inhibitor, hydrolase |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 50621.80 |
Authors | Monzingo, A.F.,Fast, W.,Thomas, P.W. (deposition date: 2019-05-08, release date: 2019-06-12, Last modification date: 2023-11-15) |
Primary citation | Thomas, P.W.,Cammarata, M.,Brodbelt, J.S.,Monzingo, A.F.,Pratt, R.F.,Fast, W. A Lysine-Targeted Affinity Label for Serine-beta-Lactamase Also Covalently Modifies New Delhi Metallo-beta-lactamase-1 (NDM-1). Biochemistry, 58:2834-2843, 2019 Cited by PubMed: 31145588DOI: 10.1021/acs.biochem.9b00393 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.017 Å) |
Structure validation
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