6OVZ

Crystal structure of the New Delhi metallo-beta-lactamase-1 adduct with a lysine-targeted affinity label

Summary for 6OVZ

• Entry DOI: 10.2210/pdb6ovz/pdb
• Descriptor: Beta-lactamase, ZINC ION, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: ndm-1, affinity-label, covalent inhibitor, hydrolase
• Biological source: Escherichia coli; More
• Total number of polymer chains: 2
• Total formula weight: 50621.80

Authors

Monzingo, A.F.,Fast, W.,Thomas, P.W. (deposition date: 2019-05-08, release date: 2019-06-12, Last modification date: 2023-11-15)

• Primary citation: Thomas, P.W.,Cammarata, M.,Brodbelt, J.S.,Monzingo, A.F.,Pratt, R.F.,Fast, W.; A Lysine-Targeted Affinity Label for Serine-beta-Lactamase Also Covalently Modifies New Delhi Metallo-beta-lactamase-1 (NDM-1).; Biochemistry, 58:2834-2843, 2019; PubMed: 31145588; DOI: 10.1021/acs.biochem.9b00393

Experimental method

X-RAY DIFFRACTION (2.017 Å)