6RQC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rqc by Molmil](/molmil-images/mine/6rqc) | Cryo-EM structure of an MCM loading intermediate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (88-MER), ... | Authors: | Miller, T.C.R, Locke, J, Costa, A. | Deposit date: | 2019-05-15 | Release date: | 2019-11-20 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM. Nature, 575, 2019
|
|
4UP5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4up5 by Molmil](/molmil-images/mine/4up5) | Crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a chemical fragment | Descriptor: | 6-methoxy-1,3-benzothiazol-2-amine, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... | Authors: | Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. | Deposit date: | 2014-06-12 | Release date: | 2014-11-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9, 2014
|
|
4UP0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4up0 by Molmil](/molmil-images/mine/4up0) | Ternary crystal structure of the Pygo2 PHD finger in complex with the B9L HD1 domain and a H3K4me2 peptide | Descriptor: | HISTONE H3.1, PYGOPUS HOMOLOG 2, B-CELL CLL/LYMPHOMA 9-LIKE PROTEIN, ... | Authors: | Miller, T.C.R, Fiedler, M, Rutherford, T.J, Birchall, K, Chugh, J, Bienz, M. | Deposit date: | 2014-06-11 | Release date: | 2014-11-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger. Acs Chem.Biol., 9, 2014
|
|
3ZPV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zpv by Molmil](/molmil-images/mine/3zpv) | Crystal structure of Drosophila Pygo PHD finger in complex with Legless HD1 domain | Descriptor: | PROTEIN BCL9 HOMOLOG, PROTEIN PYGOPUS, ZINC ION | Authors: | Miller, T.C.R, Mieszczanek, J, Sanchez-Barrena, M.J, Rutherford, T.J, Fiedler, M, Bienz, M. | Deposit date: | 2013-03-02 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Evolutionary Adaptation of the Fly Pygo Phd Finger Towards Recognizing Histone H3 Tail Methylated at Arginine 2 Structure, 21, 2013
|
|
2XB1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xb1 by Molmil](/molmil-images/mine/2xb1) | Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ... | Authors: | Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M. | Deposit date: | 2010-04-01 | Release date: | 2010-07-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor. J.Mol.Biol., 401, 2010
|
|
6HGC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6hgc by Molmil](/molmil-images/mine/6hgc) | Structure of Calypso in complex with DEUBAD of ASX | Descriptor: | Polycomb protein Asx, Ubiquitin carboxyl-terminal hydrolase calypso,Ubiquitin carboxyl-terminal hydrolase calypso | Authors: | De, I, Chittock, E.C, Groetsch, H, Miller, T.C.R, McCarthy, A.A, Mueller, C.W. | Deposit date: | 2018-08-23 | Release date: | 2019-01-23 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structural Basis for the Activation of the Deubiquitinase Calypso by the Polycomb Protein ASX. Structure, 27, 2019
|
|
7P30
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p30 by Molmil](/molmil-images/mine/7p30) | 3.0 A resolution structure of a DNA-loaded MCM double hexamer | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (53-MER), ... | Authors: | Greiwe, J.F, Miller, T.C.R, Martino, F, Costa, A. | Deposit date: | 2021-07-06 | Release date: | 2022-02-02 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase. Nat.Struct.Mol.Biol., 29, 2022
|
|
7P5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p5z by Molmil](/molmil-images/mine/7p5z) | Structure of a DNA-loaded MCM double hexamer engaged with the Dbf4-dependent kinase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 7, ... | Authors: | Greiwe, J.F, Miller, T.C.R, Martino, F, Costa, A. | Deposit date: | 2021-07-15 | Release date: | 2022-02-02 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural mechanism for the selective phosphorylation of DNA-loaded MCM double hexamers by the Dbf4-dependent kinase. Nat.Struct.Mol.Biol., 29, 2022
|
|