3L2Y
 
 | | The structure of C-reactive protein bound to phosphoethanolamine | | 分子名称: | C-reactive protein, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER | | 著者 | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | | 登録日 | 2009-12-15 | | 公開日 | 2010-12-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component.
J.Mol.Recognit., 24, 2011
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7Z1A
 | | Nanobody H11 and F2 bound to RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F2 Nanobody, H11 Nanobody, ... | | 著者 | Mikolajek, H, Naismith, J.H. | | 登録日 | 2022-02-24 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z1D
 | | Nanobody H11-H6 bound to RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, H11-H6 nanobody, ... | | 著者 | Mikolajek, H, Naismith, J.H. | | 登録日 | 2022-02-24 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z1C
 | | Nanobody H11-B5 and H11-F2 bound to RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Nanobody B5, ... | | 著者 | Mikolajek, H, Naismith, J.H. | | 登録日 | 2022-02-24 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z1B
 | | Nanobody H11-A10 and F2 bound to RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody A10, Nanobody F2, ... | | 著者 | Mikolajek, H, Naismith, J.H. | | 登録日 | 2022-02-24 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7Z1E
 | | Nanobody H11-H4 Q98R H100E bound to RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, H11-H4 Q98R H100E, ... | | 著者 | Mikolajek, H, Naismith, J.H. | | 登録日 | 2022-02-24 | | 公開日 | 2022-03-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7ZCK
 | | Room temperature crystal structure of PhnD from Synechococcus MITS9220 in complex with phosphate | | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Phosphonate ABC type transporter/ substrate binding component | | 著者 | Mikolajek, H, Shah, B.S, Paulsen, I.T, Sandy, J, Sanchez-Weatherby, J. | | 登録日 | 2022-03-28 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Protein-to-structure pipeline for ambient-temperature in situ crystallography at VMXi.
Iucrj, 10, 2023
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3KQR
 | | The structure of serum amyloid p component bound to phosphoethanolamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... | | 著者 | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | | 登録日 | 2009-11-17 | | 公開日 | 2010-12-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component.
J.Mol.Recognit., 24, 2011
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5OQI
 | | Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C E63A mutant, beta-2microglobulin, and ovalbumin-derived peptide | | 分子名称: | Beta-2-microglobulin,H-2 class I histocompatibility antigen, K-B alpha chain | | 著者 | Mikolajek, H, Werner, J.M, Beton, M.E. | | 登録日 | 2017-08-11 | | 公開日 | 2018-04-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1.
J. Biol. Chem., 293, 2018
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5OQH
 | | Crystal Structure of a disulfide trapped single chain trimer composed of the MHC I heavy chain H-2Kb Y84C K66A mutant, beta-2microglobulin, and ovalbumin-derived peptide | | 分子名称: | Beta-2-microglobulin,H-2 class I histocompatibility antigen, K-B alpha chain | | 著者 | Mikolajek, H, Werner, J.M, Beton, M.E. | | 登録日 | 2017-08-11 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The partial dissociation of MHC class I-bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1.
J. Biol. Chem., 293, 2018
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5OQG
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5OQF
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4IHK
 | | Crystal structure of the Collagen VI alpha3 N5 domain R1061Q | | 分子名称: | Collagen alpha3(VI) | | 著者 | Mikolajek, H, Becker, A.K.A, Paulsson, M, Wagener, R, Werner, J.M. | | 登録日 | 2012-12-19 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein
Structure, 22, 2014
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4IGI
 | | Crystal structure of the Collagen VI alpha3 N5 domain | | 分子名称: | Collagen alpha3(VI) | | 著者 | Mikolajek, H, Becker, A.K.A, Paulsson, M, Wagener, R, Werner, J.M. | | 登録日 | 2012-12-17 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | A structure of a collagen VI VWA domain displays N and C termini at opposite sides of the protein
Structure, 22, 2014
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8OWT
 | | SARS-CoV-2 spike RBD with A8 and H3 nanobodies bound | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody A8, ... | | 著者 | Mikolajek, H, Naismith, J.H, Owens, R.J. | | 登録日 | 2023-04-28 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
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8OWV
 | | H6 and F2 nanobodies bound to SARS-CoV-2 spike RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F2, GLYCEROL, ... | | 著者 | Mikolajek, H, Naismith, J.H, Owens, R.J. | | 登録日 | 2023-04-28 | | 公開日 | 2024-05-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
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8CIF
 | | Bovine naive ultralong antibody AbD08 collected at 293K | | 分子名称: | Heavy chain, Light chain | | 著者 | Clarke, J.D, Mikolajek, H, Stuart, D.I, Owens, R.J. | | 登録日 | 2023-02-09 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-07-19 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Protein-to-structure pipeline for ambient-temperature in situ crystallography at VMXi.
Iucrj, 10, 2023
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7S6G
 | | Crystal structure of PhnD from Synechococcus MITS9220 in complex with phosphate | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | | 著者 | Shah, B.S, Mikolajek, H, Orr, C.M, Mykhaylyk, V, Owens, R.J, Paulsen, I.T. | | 登録日 | 2021-09-14 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Marine picocyanobacterial PhnD1 shows specificity for various phosphorus sources but likely represents a constitutive inorganic phosphate transporter.
Isme J, 17, 2023
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7S6E
 | | Crystal structure of UrtA from Synechococcus CC9311 in complex with urea and calcium | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Shah, B.S, Mikolajek, H, Mykhaylyk, V, Orr, C.M, Owens, R.J, Paulsen, I.T. | | 登録日 | 2021-09-14 | | 公開日 | 2021-10-13 | | 実験手法 | X-RAY DIFFRACTION (1.973 Å) | | 主引用文献 | Crystal structure of UrtA from Synechococcus CC9311 in complex with urea and calcium
To Be Published
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7S6F
 | | Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Putative urea ABC transporter, ... | | 著者 | Shah, B.S, Mikolajek, H, Orr, C.M, Mykhaylyk, V, Owens, R.J, Paulsen, I.T. | | 登録日 | 2021-09-14 | | 公開日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of UrtA1 from Synechococcus WH8102 in complex with urea and calcium
To Be Published
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7UG8
 | | Crystal structure of a solute receptor from Synechococcus CC9311 in complex with alpha-ketovaleric and calcium | | 分子名称: | 1,2-ETHANEDIOL, 2-oxopentanoic acid, CALCIUM ION, ... | | 著者 | Shah, B.S, Mikolajek, H, Orr, C.M, Mykhaylyk, V, Owens, R.J, Paulsen, I.T. | | 登録日 | 2022-03-24 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.796 Å) | | 主引用文献 | Crystal structure of a solute receptor from Synechococcus CC9311 in complex with alpha-ketovaleric and calcium
To Be Published
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2IZP
 | | BipD - an invasion protein associated with the type-III secretion system of Burkholderia pseudomallei. | | 分子名称: | PUTATIVE MEMBRANE ANTIGEN | | 著者 | Erskine, P.T, Knight, M.J, Ruaux, A, Mikolajek, H, Wong-Fat-Sang, N, Withers, J, Gill, R, Wood, S.P, Wood, M, Fox, G.C, Cooper, J.B. | | 登録日 | 2006-07-25 | | 公開日 | 2006-09-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High Resolution Structure of Bipd: An Invasion Protein Associated with the Type III Secretion System of Burkholderia Pseudomallei.
J.Mol.Biol., 363, 2006
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7Z59
 | | SARS-CoV-2 main protease (Mpro) covalently modified with a penicillin derivative | | 分子名称: | (3S)-4-[[2,4-bis(fluoranyl)phenyl]methoxy]-2-methyl-4-oxidanylidene-3-[[(Z)-3-oxidanylidene-2-(2-phenoxyethanoylamino)prop-1-enyl]amino]butane-2-sulfinic acid, 1,2-ETHANEDIOL, 3C-like proteinase nsp5 | | 著者 | Owen, C.D, Malla, T.R, Brewitz, L, Lukacik, P, Strain-Damerell, C, Mikolajek, H, Muntean, D.G, Aslam, H, Salah, E, Tumber, A, Schofield, C.J, Walsh, M.A. | | 登録日 | 2022-03-08 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Penicillin Derivatives Inhibit the SARS-CoV-2 Main Protease by Reaction with Its Nucleophilic Cysteine.
J.Med.Chem., 65, 2022
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7OAQ
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7OAP
 | | Nanobody H3 AND C1 bound to RBD | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C1 nanobody, CHLORIDE ION, ... | | 著者 | Naismith, J.H, Mikolajek, H. | | 登録日 | 2021-04-19 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19.
Nat Commun, 12, 2021
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