7Z1A

Nanobody H11 and F2 bound to RBD

Summary for 7Z1A

Entry DOI	10.2210/pdb7z1a/pdb
Descriptor	Spike protein S1, F2 Nanobody, H11 Nanobody, ... (5 entities in total)
Functional Keywords	spike, nanobody, high affinity, antiviral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	6
Total formula weight	107535.96
Authors	Mikolajek, H.,Naismith, J.H. (deposition date: 2022-02-24, release date: 2022-03-23, Last modification date: 2024-01-31)
Primary citation	Mikolajek, H.,Weckener, M.,Brotzakis, Z.F.,Huo, J.,Dalietou, E.V.,Le Bas, A.,Sormanni, P.,Harrison, P.J.,Ward, P.N.,Truong, S.,Moynie, L.,Clare, D.K.,Dumoux, M.,Dormon, J.,Norman, C.,Hussain, N.,Vogirala, V.,Owens, R.J.,Vendruscolo, M.,Naismith, J.H. Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes. Proc.Natl.Acad.Sci.USA, 119:e2205412119-e2205412119, 2022 Cited by PubMed: 35858383 DOI: 10.1073/pnas.2205412119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation