7Z1D

Nanobody H11-H6 bound to RBD

This is a non-PDB format compatible entry.

Summary for 7Z1D

• Entry DOI: 10.2210/pdb7z1d/pdb
• Descriptor: Spike protein S1, H11-H6 nanobody, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: spike, nanobody, high affinity, antiviral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2; More
• Total number of polymer chains: 2
• Total formula weight: 38927.54

Authors

Mikolajek, H.,Naismith, J.H. (deposition date: 2022-02-24, release date: 2022-03-23, Last modification date: 2024-01-31)

• Primary citation: Mikolajek, H.,Weckener, M.,Brotzakis, Z.F.,Huo, J.,Dalietou, E.V.,Le Bas, A.,Sormanni, P.,Harrison, P.J.,Ward, P.N.,Truong, S.,Moynie, L.,Clare, D.K.,Dumoux, M.,Dormon, J.,Norman, C.,Hussain, N.,Vogirala, V.,Owens, R.J.,Vendruscolo, M.,Naismith, J.H.; Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes.; Proc.Natl.Acad.Sci.USA, 119:e2205412119-e2205412119, 2022; PubMed: 35858383; DOI: 10.1073/pnas.2205412119

Experimental method

X-RAY DIFFRACTION (1.55 Å)