PDB Search results for query - Protein Data Bank Japan

PDB: 139 results

Protein Tyrosine Phosphatase (putative) from Leishmania major
Descriptor:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase-like protein, THIOSULFATE
Authors:	Merritt, E.A, Arakaki, T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP), Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2011-05-19
Release date:	2011-06-15
Last modified:	2024-10-09
Method:	X-RAY DIFFRACTION (2.3 Å)
Cite:	Protein Tyrosine Phosphatase from Leishmania major To be Published

3P0I

Leishmania major Tyrosyl-tRNA synthetase in complex with tyrosinol, cubic crystal form
Descriptor:	4-[(2S)-2-amino-3-hydroxypropyl]phenol, Tyrosyl-tRNA synthetase
Authors:	Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:	2010-09-28
Release date:	2011-03-23
Last modified:	2023-12-06
Method:	X-RAY DIFFRACTION (3.13 Å)
Cite:	The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer. J.Mol.Biol., 409, 2011

2CHB

CHOLERA TOXIN B-PENTAMER COMPLEXED WITH GM1 PENTASACCHARIDE
Descriptor:	CHOLERA TOXIN, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	1997-06-03
Release date:	1997-12-03
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Structural studies of receptor binding by cholera toxin mutants. Protein Sci., 6, 1997

3V51

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor RM-1-176
Descriptor:	3-{6-[(3-chlorobenzyl)oxy]naphthalen-2-yl}-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2011-12-15
Release date:	2012-03-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012

3V5P

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1288
Descriptor:	3-(4-methoxy-3-methylphenyl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2011-12-16
Release date:	2012-03-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012

3UPX

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1300
Descriptor:	Calmodulin-domain protein kinase 1, [2-amino-1-(piperidin-4-ylmethyl)-1H-benzimidazol-6-yl](phenyl)methanone
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2011-11-18
Release date:	2012-03-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.27 Å)
Cite:	Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012

3UPZ

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with bumpless BKI analog UW1243
Descriptor:	1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2011-11-18
Release date:	2012-03-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012

3UQF

c-SRC kinase domain in complex with BKI RM-1-89
Descriptor:	3-(6-ethoxynaphthalen-2-yl)-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2011-11-20
Release date:	2012-03-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.27 Å)
Cite:	Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012

3V5T

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1299
Descriptor:	1-[(2S)-2-(dimethylamino)-3-methylbutyl]-3-(6-ethoxynaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2011-12-16
Release date:	2012-03-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.13 Å)
Cite:	Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012

3UQG

c-SRC kinase domain in complex with bumpless BKI analog UW1243
Descriptor:	1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2011-11-20
Release date:	2012-03-14
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012

4EQU

Human STK-10 (LOK) kinase domain in DFG-out conformation with inhibitor DSA-7
Descriptor:	CALCIUM ION, N-{3-[(3-{4-[(4-methoxyphenyl)amino]-1,3,5-triazin-2-yl}pyridin-2-yl)amino]-4-methylphenyl}-3-(trifluoromethyl)benzamide, PENTAETHYLENE GLYCOL, ...
Authors:	Merritt, E.A, Larson, E.T.
Deposit date:	2012-04-19
Release date:	2012-11-07
Last modified:	2012-12-19
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Affinity-Based Probes Based on Type II Kinase Inhibitors. J.Am.Chem.Soc., 134, 2012

4DS2

Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi
Descriptor:	Ubiquitin-conjugating enzyme E2, putative
Authors:	Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2012-02-17
Release date:	2012-02-29
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.63 Å)
Cite:	Ubiquitin conjugating enzyme (putative) from Trypanosoma cruzi To be Published

1EEI

CHOLERA TOXIN B-PENTAMER COMPLEXED WITH METANITROPHENYL-ALPHA-D-GALACTOSE
Descriptor:	3-nitrophenyl alpha-D-galactopyranoside, PROTEIN (CHOLERA TOXIN B)
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	2000-01-31
Release date:	2000-02-16
Last modified:	2023-08-09
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives. Acta Crystallogr.,Sect.D, 57, 2001

1EFI

HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH PARA-AMINOPHENYL-ALPHA-D-GALACTOPYRANOSIDE
Descriptor:	4-aminophenyl alpha-D-galactopyranoside, PROTEIN (HEAT-LABILE ENTEROTOXIN B CHAIN)
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	2000-02-08
Release date:	2000-02-23
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives. Acta Crystallogr.,Sect.D, 57, 2001

3BNW

Crystal structure of riboflavin kinase from Trypanosoma brucei
Descriptor:	Riboflavin kinase, putative
Authors:	Merritt, E.A, Holmes, M, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2007-12-14
Release date:	2008-01-08
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Riboflavin kinase from Trypanosoma brucei. To be Published

1QCB

ESCHERICHIA COLI HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER
Descriptor:	PROTEIN (HEAT LABILE ENTEROTOXIN TYPE IIB B-PENTAMER)
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	1999-04-30
Release date:	2003-06-10
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Crystal Structures of the B-Pentamer from E. coli Enterotoxin LT-IIb To be Published

3SO4

Methionine-adenosyltransferase from Entamoeba histolytica
Descriptor:	ACETATE ION, Methionine-adenosyltransferase
Authors:	Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:	2011-06-29
Release date:	2011-07-20
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (3.18 Å)
Cite:	Methionine-adenosyltransferase from Entamoeba histolytica To be Published

5SWH

c-Src V281C kinase domain in complex with Rao-IV-151
Descriptor:	(2R)-3-[4-amino-5-(4-chlorophenyl)-7-(2-methoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-cyano-N-(propan-2-yl)propanami de, Proto-oncogene tyrosine-protein kinase Src
Authors:	Merritt, E.A, Dieter, E.M.
Deposit date:	2016-08-08
Release date:	2017-08-16
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	A combined approach reveals a regulatory mechanism coupling Src's kinase activity, localization, and phosphotransferase-independent functions Mol.Cell, 2019

1CHQ

SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor:	CHOLERA TOXIN B PENTAMER
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	1995-02-15
Release date:	1996-03-08
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants. Structure, 3, 1995

1CHP

SURPRISING LEADS FOR A CHOLERA TOXIN RECEPTOR BINDING ANTAGONIST; CRYSTALLOGRAPHIC STUDIES OF CTB MUTANTS
Descriptor:	CHLORIDE ION, CHOLERA TOXIN B PENTAMER
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	1995-02-15
Release date:	1996-03-08
Last modified:	2021-11-03
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants. Structure, 3, 1995

1EEF

HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH BOUND LIGAND PEPG
Descriptor:	2-PHENETHYL-2,3-DIHYDRO-PHTHALAZINE-1,4-DIONE, PROTEIN (HEAT-LABILE ENTEROTOXIN B CHAIN), alpha-D-galactopyranose
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	2000-01-31
Release date:	2000-02-16
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives. Acta Crystallogr.,Sect.D, 57, 2001

1LT5

HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH THIODIGALACTOSIDE
Descriptor:	HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	1997-09-30
Release date:	1997-12-03
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin. Structure, 5, 1997

1LT6

HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH METANITROPHENYLGALACTOSIDE
Descriptor:	3-nitrophenyl alpha-D-galactopyranoside, HEAT-LABILE ENTEROTOXIN
Authors:	Merritt, E.A, Hol, W.G.J.
Deposit date:	1997-10-01
Release date:	1997-12-03
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin. Structure, 5, 1997

3LC0

Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidine complex)
Descriptor:	HISTIDINE, Histidyl-tRNA synthetase
Authors:	Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:	2010-01-08
Release date:	2010-01-19
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs. J.Mol.Biol., 397, 2010

1VJQ

Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability.
Descriptor:	designed protein
Authors:	Merritt, E.A, Baker, D, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:	2004-03-19
Release date:	2004-03-30
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (2.098 Å)
Cite:	Designed protein based on backbone conformation of procarboxypeptidase-A (1AYE) with sidechains chosen for maximal predicted stability. To be Published

<123 4 5 6 >

Total results:	139
Displayed results:	25
Sorted by:	Hit score (from highest)
Deposition authors:	"Merritt, E.A"