Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 12 results
4TSE
DownloadVisualize
BU of 4tse by Molmil
Crystal Structure of the Mib Repeat Domain of Mind bomb 1
Descriptor: E3 ubiquitin-protein ligase MIB1
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2014-06-18
Release date:2015-03-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.057 Å)
Cite:A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
6V0O
DownloadVisualize
BU of 6v0o by Molmil
PRMT5 bound to the PBM peptide from pICln
Descriptor: ACETYL GROUP, Methylosome protein 50, PBM peptide, ...
Authors:McMillan, B.J, Raymond, D.D.
Deposit date:2019-11-19
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol.Cell, 81, 2021
5J45
DownloadVisualize
BU of 5j45 by Molmil
Crystal structure of Shrub, fly ortholog of SNF7/CHMP4B
Descriptor: GH13992p
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2016-03-31
Release date:2016-07-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.758 Å)
Cite:Electrostatic Interactions between Elongated Monomers Drive Filamentation of Drosophila Shrub, a Metazoan ESCRT-III Protein.
Cell Rep, 16, 2016
7M05
DownloadVisualize
BU of 7m05 by Molmil
CryoEM structure of PRMT5 bound to covalent PBM-site inhibitor BRD-6988
Descriptor: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-{[2-(pyridin-2-yl)ethyl]sulfamoyl}phenyl)acetamide, Methylosome protein 50, Protein arginine N-methyltransferase 5
Authors:McMillan, B.J, McKinney, D.C, Timm, D.E.
Deposit date:2021-03-10
Release date:2021-03-17
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (2.39 Å)
Cite:Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021
6V0P
DownloadVisualize
BU of 6v0p by Molmil
PRMT5 complex bound to covalent PBM inhibitor BRD6711
Descriptor: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-sulfamoylphenyl)acetamide, CHLORIDE ION, GLYCEROL, ...
Authors:McMillan, B.J, McKinney, D.C.
Deposit date:2019-11-19
Release date:2020-11-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021
6V0N
DownloadVisualize
BU of 6v0n by Molmil
PRMT5 bound to PBM peptide from Riok1
Descriptor: Methylosome protein 50, Protein arginine N-methyltransferase 5, Riok1 PBM peptide, ...
Authors:McMIllan, B.J, Raymond, D.D.
Deposit date:2019-11-19
Release date:2020-08-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Molecular basis for substrate recruitment to the PRMT5 methylosome.
Mol.Cell, 81, 2021
4XI7
DownloadVisualize
BU of 4xi7 by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with Jagged1 N-box peptide
Descriptor: E3 ubiquitin-protein ligase MIB1, Jagged 1 N-box peptide, SULFATE ION, ...
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2015-01-06
Release date:2015-03-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
4XIB
DownloadVisualize
BU of 4xib by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with fly Delta N-box peptide
Descriptor: Delta N-box peptide, E3 ubiquitin-protein ligase MIB1, SULFATE ION, ...
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2015-01-06
Release date:2015-03-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.147 Å)
Cite:A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
4XI6
DownloadVisualize
BU of 4xi6 by Molmil
Crystal structure of the MZM-REP domains of Mind bomb 1
Descriptor: E3 ubiquitin-protein ligase MIB1, SULFATE ION, ZINC ION
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2015-01-06
Release date:2015-03-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:A tail of two sites: a bipartite mechanism for recognition of notch ligands by mind bomb e3 ligases.
Mol.Cell, 57, 2015
5VNY
DownloadVisualize
BU of 5vny by Molmil
Crystal structure of DM14-3 domain of Lgd
Descriptor: Lethal (2) giant discs 1, isoform B
Authors:McMillan, B.J, Blacklow, S.C.
Deposit date:2017-05-01
Release date:2017-06-14
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.101 Å)
Cite:Structural Basis for Regulation of ESCRT-III Complexes by Lgd.
Cell Rep, 19, 2017
5VO5
DownloadVisualize
BU of 5vo5 by Molmil
Crystal structure of Lgd-Shrub complex, single chain fusion
Descriptor: Coiled-coil and C2 domain-containing protein 1-like,GH13992p
Authors:McMillan, B.J, Seegar, T.C.M, Blacklow, S.C.
Deposit date:2017-05-02
Release date:2017-06-14
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural Basis for Regulation of ESCRT-III Complexes by Lgd.
Cell Rep, 19, 2017
5TCX
DownloadVisualize
BU of 5tcx by Molmil
Crystal structure of human tetraspanin CD81
Descriptor: CD81 antigen, CHOLESTEROL
Authors:Zimmerman, B, McMillan, B.J, Seegar, T.C.M, Kruse, A.C, Blacklow, S.C.
Deposit date:2016-09-16
Release date:2016-11-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.955 Å)
Cite:Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket.
Cell, 167, 2016

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon