8VTL
 
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8VTM
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8VTK
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8VTN
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3HAT
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7MHA
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8EIW
 | | Cobalt(II)-substituted Horse Liver Alcohol Dehydrogenase in Complex with NADH and N-Cyclohexylformamide | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alcohol dehydrogenase E chain, COBALT (II) ION, ... | | 著者 | Zheng, C, Mathews, I.I, Boxer, S.G. | | 登録日 | 2022-09-15 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Enhanced active-site electric field accelerates enzyme catalysis.
Nat.Chem., 15, 2023
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8EIY
 | | Cobalt(II)-substituted S48T Horse Liver Alcohol Dehydrogenase in Complex with NADH and N-Cyclohexylformamide | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alcohol dehydrogenase E chain, COBALT (II) ION, ... | | 著者 | Zheng, C, Mathews, I.I, Boxer, S.G. | | 登録日 | 2022-09-15 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Enhanced active-site electric field accelerates enzyme catalysis.
Nat.Chem., 15, 2023
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8EIX
 | | Cobalt(II)-substituted S48A Horse Liver Alcohol Dehydrogenase in Complex with NADH and N-Cyclohexylformamide | | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alcohol dehydrogenase E chain, COBALT (II) ION, ... | | 著者 | Zheng, C, Mathews, I.I, Boxer, S.G. | | 登録日 | 2022-09-15 | | 公開日 | 2023-02-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Enhanced active-site electric field accelerates enzyme catalysis.
Nat.Chem., 15, 2023
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8EE1
 | | KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment AA5 | | 分子名称: | 6-deoxyerythronolide B synthase, AA5 antibody heavy chain, AA5 antibody light chain | | 著者 | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | | 登録日 | 2022-09-06 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase.
Biochemistry, 62, 2023
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8ECT
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8ECU
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8ECS
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6WH9
 | | Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 1D10 | | 分子名称: | 1D10 (Fab heavy chain), 1D10 (Fab light chain), KR1, ... | | 著者 | Cogan, D.P, Mathews, I.I, Khosla, C. | | 登録日 | 2020-04-07 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction.
J.Am.Chem.Soc., 142, 2020
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6V2J
 | | Crystal structure of ClC-ec1 triple mutant (E113Q, E148Q, E203Q) | | 分子名称: | CHLORIDE ION, H(+)/Cl(-) exchange transporter ClcA | | 著者 | Maduke, M, Mathews, I.I, Chavan, T.S. | | 登録日 | 2019-11-24 | | 公開日 | 2020-05-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl - /H + transport cycle.
Elife, 9, 2020
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8EE0
 | | KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment 1B2 | | 分子名称: | 1B2 antibody heavy chain, 1B2 antibody light chain, 6-deoxyerythronolide B synthase | | 著者 | Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C. | | 登録日 | 2022-09-06 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase.
Biochemistry, 62, 2023
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6W7S
 | | Ketoreductase from module 1 of the 6-deoxyerythronolide B synthase (KR1) in complex with antibody fragment (Fab) 2G10 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2G10 (Fab heavy chain), 2G10 (Fab light chain), ... | | 著者 | Cogan, D.P, Mathews, I.I, Khosla, C. | | 登録日 | 2020-03-19 | | 公開日 | 2020-09-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction.
J.Am.Chem.Soc., 142, 2020
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2NM0
 | | Crystal Structure of SCO1815: a Beta-Ketoacyl-Acyl Carrier Protein Reductase from Streptomyces coelicolor A3(2) | | 分子名称: | Probable 3-oxacyl-(Acyl-carrier-protein) reductase | | 著者 | Khosla, C, Tang, Y, Lee, H.Y, Tang, Y, Kim, C.Y, Mathews, I.I. | | 登録日 | 2006-10-20 | | 公開日 | 2007-01-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural and functional studies on SCO1815: a beta-ketoacyl-acyl carrier protein reductase from Streptomyces coelicolor A3(2).
Biochemistry, 45, 2006
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6OFN
 | | Crystal structure of green fluorescent protein (GFP); S65T, T203(3-OMeY); ih circular permutant (50-51) | | 分子名称: | Green fluorescent protein (GFP); S65T, T203(3-OMeY); ih circular permutant (50-51) | | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | | 登録日 | 2019-03-31 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.649 Å) | | 主引用文献 | Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins.
J.Am.Chem.Soc., 141, 2019
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6OFK
 | | Crystal structure of green fluorescent protein (GFP); S65T; ih circular permutant (50-51) | | 分子名称: | ACETATE ION, Green Fluorescent Protein (GFP); S65T; ih circular permutant (50-51) | | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | | 登録日 | 2019-03-30 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins.
J.Am.Chem.Soc., 141, 2019
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6OFL
 | | Crystal structure of green fluorescent protein (GFP); S65T, Y66(3-ClY); ih circular permutant (50-51) | | 分子名称: | Green fluorescent protein (GFP); S65T, Y66(3-ClY); ih circular permutant (50-51) | | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | | 登録日 | 2019-03-31 | | 公開日 | 2019-07-10 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Unified Model for Photophysical and Electro-Optical Properties of Green Fluorescent Proteins.
J.Am.Chem.Soc., 141, 2019
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6NQS
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6NQN
 | | Crystal structure of fast switching M159T mutant of fluorescent protein Dronpa (Dronpa2), Y63(3-BrY) | | 分子名称: | Fluorescent protein Dronpa | | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | | 登録日 | 2019-01-21 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Electrostatic control of photoisomerization pathways in proteins.
Science, 367, 2020
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6NQV
 | | Crystal structure of fast switching M159T mutant of fluorescent protein Dronpa (Dronpa2), Y63(3-CH3Y) | | 分子名称: | Fluorescent protein Dronpa | | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | | 登録日 | 2019-01-22 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Electrostatic control of photoisomerization pathways in proteins.
Science, 367, 2020
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6NQK
 | | Crystal structure of fast switching M159T mutant of fluorescent protein Dronpa (Dronpa2), Y63(3-FY) | | 分子名称: | Fluorescent protein Dronpa | | 著者 | Lin, C.-Y, Romei, M.G, Mathews, I.I, Boxer, S.G. | | 登録日 | 2019-01-21 | | 公開日 | 2019-06-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Electrostatic control of photoisomerization pathways in proteins.
Science, 367, 2020
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