2L30
| Human PARP-1 zinc finger 1 | 分子名称: | Poly [ADP-ribose] polymerase 1, ZINC ION | 著者 | Neuhaus, D, Eustermann, S, Yang, J, Videler, H. | 登録日 | 2010-08-30 | 公開日 | 2011-02-02 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger. J.Mol.Biol., 407, 2011
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4I9Y
| Structure of the C-terminal domain of Nup358 | 分子名称: | CHLORIDE ION, E3 SUMO-protein ligase RanBP2, GLYCEROL, ... | 著者 | Lin, D.H, Zimmermann, S, Stuwe, T, Stuwe, E, Hoelz, A. | 登録日 | 2012-12-05 | 公開日 | 2013-01-30 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2. J.Mol.Biol., 425, 2013
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1R3O
| Crystal structure of the first RNA duplex in L-conformation at 1.9A resolution | 分子名称: | L-RNA | 著者 | Vallazza, M, Perbandt, M, Klussmann, S, Rypniewski, W, Erdmann, V.A, Betzel, C. | 登録日 | 2003-10-02 | 公開日 | 2003-12-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | First look at RNA in L-configuration. Acta Crystallogr.,Sect.D, 60, 2004
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7Z3W
| Crystal structure of the AAL160 Fab | 分子名称: | 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, AAL160 Fab heavy-chain, AAL160 Fab light-chain | 著者 | Rondeau, J.M, Lehmann, S. | 登録日 | 2022-03-02 | 公開日 | 2023-02-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | "Redirecting an anti-IL-1 beta antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A". Commun Biol, 6, 2023
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7Z4T
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7Z2M
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2V09
| SENS161-164DSSN mutant of Bacillus subtilis Oxalate Decarboxylase OxdC | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, OXALATE DECARBOXYLASE OXDC | 著者 | Burrell, M.R, Just, V.J, Bowater, L, Fairhurst, S.A, Requena, L, Lawson, D.M, Bornemann, S. | 登録日 | 2007-05-10 | 公開日 | 2007-10-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Oxalate Decarboxylase and Oxalate Oxidase Activities Can be Interchanged with a Specificity Switch of Up to 282 000 by Mutating an Active Site Lid. Biochemistry, 46, 2007
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2OJ2
| NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1) | 分子名称: | Hematopoetic Cell Kinase, SH3 domain, artificial peptide PD1 | 著者 | Schmidt, H, Hoffmann, S, Tran, T, Stoldt, M, Stangler, T, Wiesehan, K, Willbold, D. | 登録日 | 2007-01-12 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of a Hck SH3 Domain Ligand Complex Reveals Novel Interaction Modes J.Mol.Biol., 365, 2007
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8A5Q
| Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on straight DNA | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | 登録日 | 2022-06-15 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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8A5A
| Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-like protein ARP8, ... | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | 登録日 | 2022-06-14 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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8A5P
| Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on curved DNA | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ... | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | 登録日 | 2022-06-15 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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8A5O
| Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of S. cerevisiae INO80 | 分子名称: | Actin, Actin-like protein ARP8, Actin-related protein 4, ... | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | 登録日 | 2022-06-15 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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8A5D
| Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 | 分子名称: | Actin, Actin related protein 4 (Arp4), Actin-related protein 8, ... | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | 登録日 | 2022-06-14 | 公開日 | 2022-12-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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2OI3
| NMR Structure Analysis of the Hematopoetic Cell Kinase SH3 Domain complexed with an artificial high affinity ligand (PD1) | 分子名称: | Tyrosine-protein kinase HCK, artificial peptide PD1 | 著者 | Schmidt, H, Stoldt, M, Hoffmann, S, Tran, T, Willbold, D. | 登録日 | 2007-01-10 | 公開日 | 2007-02-20 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of a Hck SH3 Domain Ligand
Complex Reveals Novel Interaction Modes J.Mol.Biol., 365, 2007
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8C3U
| Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist | 分子名称: | (S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid, Interleukin-1 beta | 著者 | Rondeau, J.-M, Lehmann, S, Koch, E. | 登録日 | 2022-12-28 | 公開日 | 2023-09-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | 主引用文献 | Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1 beta. Nat Commun, 14, 2023
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1RI4
| Structure and mechanism of mRNA cap (guanine N-7) methyltransferase | 分子名称: | S-ADENOSYLMETHIONINE, mRNA CAPPING ENZYME | 著者 | Fabrega, C, Hausmann, S, Shen, V, Shuman, S, Lima, C.D. | 登録日 | 2003-11-16 | 公開日 | 2004-02-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure and mechanism of mRNA cap (Guanine-n7) methyltransferase Mol.Cell, 13, 2004
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8OO7
| CryoEM Structure INO80core Hexasome complex composite model state1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ... | 著者 | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | 登録日 | 2023-04-04 | 公開日 | 2023-07-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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8OOP
| CryoEM Structure INO80core Hexasome complex composite model state2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ... | 著者 | Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S. | 登録日 | 2023-04-05 | 公開日 | 2023-07-26 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling. Science, 381, 2023
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1TR7
| FimH adhesin receptor binding domain from uropathogenic E. coli | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, FimH protein, ... | 著者 | Bouckaert, J, Berglund, J, Schembri, M, De Genst, E, Cools, L, Wuhrer, M, Hung, C.S, Pinkner, J, Slattegard, R, Zavialov, A, Choudhury, D, Langermann, S, Hultgren, S.J, Wyns, L, Klemm, P, Oscarson, S, Knight, S.D, De Greve, H. | 登録日 | 2004-06-21 | 公開日 | 2005-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin Mol.Microbiol., 55, 2005
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6RAH
| Heterodimeric ABC exporter TmrAB in ATP-bound outward-facing open conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Multidrug resistance ABC transporter ATP-binding and permease protein, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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6RAM
| Heterodimeric ABC exporter TmrAB under turnover conditions in asymmetric unlocked return conformation with wider opened intracellular gate | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Thomas, C, Januliene, D, Mehdipour, A.R, Hofmann, S, Hummer, G, Moeller, A, Tampe, R. | 登録日 | 2019-04-06 | 公開日 | 2019-07-31 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Conformation space of a heterodimeric ABC exporter under turnover conditions. Nature, 571, 2019
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8ATF
| Nucleosome-bound Ino80 ATPase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (226-MER), DNA (227-MER), ... | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | 登録日 | 2022-08-23 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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8AV6
| CryoEM structure of INO80 core nucleosome complex in closed grappler conformation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DASH complex subunit DAD4, ... | 著者 | Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P. | 登録日 | 2022-08-26 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.68 Å) | 主引用文献 | Structural mechanism of extranucleosomal DNA readout by the INO80 complex. Sci Adv, 8, 2022
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4LJ0
| Nab2 Zn fingers complexed with polyadenosine | 分子名称: | ACETATE ION, MAGNESIUM ION, Nab2, ... | 著者 | Stewart, M, Kuhlmann, S.I, Valkov, E. | 登録日 | 2013-07-04 | 公開日 | 2013-10-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers. Nucleic Acids Res., 42, 2014
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6TVP
| Structure of Mycobacterium smegmatis alpha-maltose-1-phosphate synthase GlgM | 分子名称: | Alpha-maltose-1-phosphate synthase, SODIUM ION | 著者 | Syson, K, Stevenson, C.E.M, Lawson, D.M, Bornemann, S. | 登録日 | 2020-01-10 | 公開日 | 2020-04-22 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the Mycobacterium smegmatis alpha-maltose-1-phosphate synthase GlgM. Acta Crystallogr.,Sect.F, 76, 2020
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