7Z3W

Crystal structure of the AAL160 Fab

Summary for 7Z3W

• Entry DOI: 10.2210/pdb7z3w/pdb
• Related: 7Z2M
• Descriptor: AAL160 Fab heavy-chain, AAL160 Fab light-chain, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... (4 entities in total)
• Functional Keywords: monoclonal antibody, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 49186.05

Authors

Rondeau, J.M.,Lehmann, S. (deposition date: 2022-03-02, release date: 2023-02-08, Last modification date: 2024-02-07)

• Primary citation: Fischman, S.,Levin, I.,Rondeau, J.M.,Strajbl, M.,Lehmann, S.,Huber, T.,Nimrod, G.,Cebe, R.,Omer, D.,Kovarik, J.,Bernstein, S.,Sasson, Y.,Demishtein, A.,Shlamkovich, T.,Bluvshtein, O.,Grossman, N.,Barak-Fuchs, R.,Zhenin, M.,Fastman, Y.,Twito, S.,Vana, T.,Zur, N.,Ofran, Y.; "Redirecting an anti-IL-1 beta antibody to bind a new, unrelated and computationally predicted epitope on hIL-17A".; Commun Biol, 6:997-997, 2023; PubMed: 37773269; DOI: 10.1038/s42003-023-05369-x

Experimental method

X-RAY DIFFRACTION (2 Å)