6HYE
 
 | | PDX1.2/PDX1.3 complex (PDX1.3:K97A) | | Descriptor: | Pyridoxal 5'-phosphate synthase subunit PDX1.3, Pyridoxal 5'-phosphate synthase-like subunit PDX1.2, SULFATE ION | | Authors: | Robinson, G.C, Kaufmann, M, Roux, C, Martinez-Font, J, Hothorn, M, Thore, S, Fitzpatrick, T.B. | | Deposit date: | 2018-10-20 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.53 Å) | | Cite: | Crystal structure of the pseudoenzyme PDX1.2 in complex with its cognate enzyme PDX1.3: a total eclipse.
Acta Crystallogr D Struct Biol, 75, 2019
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3IG9
 | | Small outer capsid protein (SOC) of bacteriophage RB69 | | Descriptor: | IMIDAZOLE, Soc small outer capsid protein | | Authors: | Li, Q, Fokine, A, O'Donnell, E, Rao, V.B, Rossmann, M.G. | | Deposit date: | 2009-07-27 | | Release date: | 2009-12-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the Small Outer Capsid Protein, Soc: A Clamp for Stabilizing Capsids of T4-like Phages
J.Mol.Biol., 395, 2010
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8RBZ
 | | Structure of Integrator-PP2A-SOSS-CTD post-termination complex | | Descriptor: | DNA-directed RNA polymerase subunit, DSS1, Integrator complex subunit 1, ... | | Authors: | Fianu, I, Ochmann, M, Walshe, J.L, Cramer, P. | | Deposit date: | 2023-12-05 | | Release date: | 2024-02-07 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structural basis of Integrator-dependent RNA polymerase II termination.
Nature, 629, 2024
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6G1L
 | | MITF/CLEARbox structure | | Descriptor: | CLEAR-box, Microphthalmia-associated transcription factor | | Authors: | Pogenberg, V, Wilmanns, M. | | Deposit date: | 2018-03-21 | | Release date: | 2019-02-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | MITF has a central role in regulating starvation-induced autophagy in melanoma.
Sci Rep, 9, 2019
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1FYN
 | | PHOSPHOTRANSFERASE | | Descriptor: | 3BP-2, PHOSPHOTRANSFERASE FYN | | Authors: | Musacchio, A, Saraste, M, Wilmanns, M. | | Deposit date: | 1995-05-17 | | Release date: | 1996-11-08 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.
Nat.Struct.Biol., 1, 1994
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8RDR
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8g | | Descriptor: | (5~{S})-3-(2-nitrophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | | Authors: | Bischof, L, Hartmann, M.D. | | Deposit date: | 2023-12-08 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Eur.J.Med.Chem., 270, 2024
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8RDP
 | | Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8a | | Descriptor: | (5~{S})-3-(2-chlorophenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dione, Cereblon isoform 4, PHOSPHATE ION, ... | | Authors: | Bischof, L, Hartmann, M.D. | | Deposit date: | 2023-12-08 | | Release date: | 2024-04-10 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | Discovery and characterization of potent spiro-isoxazole-based cereblon ligands with a novel binding mode.
Eur.J.Med.Chem., 270, 2024
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3GVM
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6R1X
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4LGL
 | | Crystal Structure of Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803, apo form | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Glycine dehydrogenase [decarboxylating] | | Authors: | Hasse, D, Andersson, E, Carlsson, G, Masloboy, A, Hagemann, M, Bauwe, H, Andersson, I. | | Deposit date: | 2013-06-28 | | Release date: | 2013-10-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.0004 Å) | | Cite: | Structure of the Homodimeric Glycine Decarboxylase P-protein from Synechocystis sp. PCC 6803 Suggests a Mechanism for Redox Regulation.
J.Biol.Chem., 288, 2013
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1S74
 | | SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING AN ALPHA-ANOMERIC ADENOSINE: INSIGHTS INTO SUBSTRATE RECOGNITION BY ENDONUCLEASE IV | | Descriptor: | 5'-D(*CP*GP*TP*CP*GP*TP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*(A3A)P*CP*GP*AP*CP*G)-3' | | Authors: | Aramini, J.M, Cleaver, S.H, Pon, R.T, Cunningham, R.P, Germann, M.W. | | Deposit date: | 2004-01-28 | | Release date: | 2004-04-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a DNA Duplex Containing an alpha-Anomeric Adenosine: Insights into Substrate Recognition by Endonuclease IV.
J.Mol.Biol., 338, 2004
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3IGE
 | | Small outer capsid protein (Soc) from bacteriophage RB69 | | Descriptor: | IMIDAZOLE, Soc small outer capsid protein | | Authors: | Li, Q, Fokine, A, O'Donnell, E, Rao, V.B, Rossmann, M.G. | | Deposit date: | 2009-07-27 | | Release date: | 2009-12-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.254 Å) | | Cite: | Structure of the Small Outer Capsid Protein, Soc: A Clamp for Stabilizing Capsids of T4-like Phages
J.Mol.Biol., 395, 2010
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1S0T
 | | Solution structure of a DNA duplex containing an alpha-anomeric adenosine: insights into substrate recognition by endonuclease IV | | Descriptor: | 5'-D(*Cp*Gp*Tp*Cp*Gp*Tp*Gp*Gp*Ap*C)-3', 5'-D(*Gp*Tp*Cp*Cp*(A3A)p*Cp*Gp*Ap*Cp*G)-3' | | Authors: | Aramini, J.M, Cleaver, S.H, Pon, R.T, Cunningham, R.P, Germann, M.W. | | Deposit date: | 2004-01-04 | | Release date: | 2004-04-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a DNA Duplex Containing an alpha-Anomeric Adenosine: Insights into Substrate Recognition by Endonuclease IV.
J.Mol.Biol., 338, 2004
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1S75
 | | SOLUTION STRUCTURE OF A DNA DUPLEX CONTAINING AN ALPHA-ANOMERIC ADENOSINE: INSIGHTS INTO SUBSTRATE RECOGNITION BY ENDONUCLEASE IV | | Descriptor: | 5'-D(*CP*GP*TP*CP*GP*TP*GP*GP*AP*C)-3', 5'-D(*GP*TP*CP*CP*(A3A)P*CP*GP*AP*CP*G)-3' | | Authors: | Aramini, J.M, Cleaver, S.H, Pon, R.T, Cunningham, R.P, Germann, M.W. | | Deposit date: | 2004-01-28 | | Release date: | 2004-04-20 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of a DNA Duplex Containing an alpha-Anomeric Adenosine: Insights into Substrate Recognition by Endonuclease IV.
J.Mol.Biol., 338, 2004
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4GPD
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1J7M
 | | The Third Fibronectin Type II Module from Human Matrix Metalloproteinase 2 | | Descriptor: | MATRIX METALLOPROTEINASE 2 | | Authors: | Briknarova, K, Gehrmann, M, Banyai, L, Tordai, H, Patthy, L, Llinas, M. | | Deposit date: | 2001-05-17 | | Release date: | 2001-05-30 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Gelatin-binding region of human matrix metalloproteinase-2: solution structure, dynamics, and function of the COL-23 two-domain construct.
J.Biol.Chem., 276, 2001
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1JCM
 | | TRPC STABILITY MUTANT CONTAINING AN ENGINEERED DISULPHIDE BRIDGE AND IN COMPLEX WITH A CDRP-RELATED SUBSTRATE | | Descriptor: | 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE, INDOLE-3-GLYCEROL-PHOSPHATE SYNTHASE, PHOSPHATE ION | | Authors: | Ivens, A, Mayans, O, Szadkowski, H, Wilmanns, M, Kirschner, K. | | Deposit date: | 2001-06-10 | | Release date: | 2002-06-10 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Stabilization of a (betaalpha)8-barrel protein by an engineered disulfide bridge.
Eur.J.Biochem., 269, 2002
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3ZFF
 | | Human enterovirus 71 in complex with capsid binding inhibitor WIN51711 | | Descriptor: | 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, VP1, VP2, ... | | Authors: | Plevka, P, Perera, R, Yap, M.L, Cardosa, J, Kuhn, R.J, Rossmann, M.G. | | Deposit date: | 2012-12-11 | | Release date: | 2013-03-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Structure of Human Enterovirus 71 in Complex with a Capsid-Binding Inhibitor.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4HUH
 | | Structure of the bacteriophage T4 tail terminator protein, gp15 (C-terminal truncation mutant 1-261). | | Descriptor: | Tail connector protein Gp15 | | Authors: | Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G. | | Deposit date: | 2012-11-02 | | Release date: | 2013-02-27 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
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8AZD
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6FTE
 | | Crystal structure of an (R)-selective amine transaminase from Exophiala xenobiotica | | Descriptor: | ACETATE ION, Amine transaminase (fold IV), GLYCEROL, ... | | Authors: | Telzerow, A, Hakansson, M, Schurrmann, M, Schwab, H, Steiner, K. | | Deposit date: | 2018-02-21 | | Release date: | 2019-01-09 | | Last modified: | 2020-01-29 | | Method: | X-RAY DIFFRACTION (1.52 Å) | | Cite: | Amine Transaminase from Exophiala xenobiotica - Crystal Structure and Engineering of a Fold IV Transaminase that Naturally Converts Biaryl Ketones
Acs Catalysis, 2018
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8AZL
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8AZN
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8AZI
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8AZM
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