5WVO
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![BU of 5wvo by Molmil](/molmil-images/mine/5wvo) | Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3 | Descriptor: | DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ... | Authors: | Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K. | Deposit date: | 2016-12-28 | Release date: | 2017-11-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance Mol. Cell, 68, 2017
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1OM9
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![BU of 1om9 by Molmil](/molmil-images/mine/1om9) | Structure of the GGA1-appendage in complex with the p56 binding peptide | Descriptor: | 15-mer peptide fragment of p56, ADP-ribosylation factor binding protein GGA1 | Authors: | Collins, B.M, Praefcke, G.J.K, Robinson, M.S, Owen, D.J. | Deposit date: | 2003-02-25 | Release date: | 2003-07-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for binding of accessory proteins by the appendage domain of GGAs Nat.Struct.Biol., 10, 2003
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1OWA
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![BU of 1owa by Molmil](/molmil-images/mine/1owa) | Solution Structural Studies on Human Erythrocyte Alpha Spectrin N Terminal Tetramerization Domain | Descriptor: | Spectrin alpha chain, erythrocyte | Authors: | Park, S, Caffrey, M.S, Johnson, M.E, Fung, L.W. | Deposit date: | 2003-03-28 | Release date: | 2004-03-30 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structural studies on human erythrocyte alpha-spectrin tetramerization site. J.Biol.Chem., 278, 2003
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1T2U
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![BU of 1t2u by Molmil](/molmil-images/mine/1t2u) | Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1: structure of BRCA1 missense variant V1809F | Descriptor: | Breast cancer type 1 susceptibility protein, COBALT (II) ION, SULFATE ION | Authors: | Williams, R.S, Lee, M.S, Duong, D.D, Glover, J.N.M. | Deposit date: | 2004-04-22 | Release date: | 2004-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of Phosphopeptide recognition by the BRCT domain of BRCA1 Nat.Struct.Mol.Biol., 11, 2004
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1ONV
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![BU of 1onv by Molmil](/molmil-images/mine/1onv) | NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNAP II CTD Phosphatase FCP1 | Descriptor: | Transcription initiation factor IIF, alpha subunit, serine phosphatase FCP1a | Authors: | Nguyen, B.D, Abbott, K.L, Potempa, K, Kobor, M.S, Archambault, J, Greenblatt, J, Legault, P, Omichinski, J.G. | Deposit date: | 2003-03-02 | Release date: | 2003-05-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR Structure of a Complex Containing the TFIIF Subunit RAP74 and the RNA polymerase II carboxyl-terminal domain phosphatase FCP1 Proc.Natl.Acad.Sci.USA, 100, 2003
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1T8A
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![BU of 1t8a by Molmil](/molmil-images/mine/1t8a) | USE OF SEQUENCE DUPLICATION TO ENGINEER A LIGAND-TRIGGERED LONG-DISTANCE MOLECULAR SWITCH IN T4 Lysozyme | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, GUANIDINE, ... | Authors: | Yousef, M.S, Baase, W.A, Matthews, B.W. | Deposit date: | 2004-05-11 | Release date: | 2004-08-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Use of sequence duplication to engineer a ligand-triggered, long-distance molecular switch in T4 lysozyme. Proc.Natl.Acad.Sci.USA, 101, 2004
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1T97
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![BU of 1t97 by Molmil](/molmil-images/mine/1t97) | |
1OY0
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![BU of 1oy0 by Molmil](/molmil-images/mine/1oy0) | The crystal Structure of the First Enzyme of Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase from Mycobacterium Tuberculosis Shows a Decameric Assembly and Terminal Helix-Swapping | Descriptor: | Ketopantoate hydroxymethyltransferase, MAGNESIUM ION | Authors: | Chaudhuri, B.N, Sawaya, M.R, Kim, C.Y, Waldo, G.S, Park, M.S, Terwilliger, T.C, Yeates, T.O, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-04-03 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Crystal Structure of the First Enzyme in the Pantothenate Biosynthetic Pathway,
Ketopantoate Hydroxymethyltransferase, from M. tuberculosis Structure, 11, 2003
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1PXB
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![BU of 1pxb by Molmil](/molmil-images/mine/1pxb) | CRYSTAL STRUCTURES OF MUTANT PSEUDOMONAS AERUGINOSA P-HYDROXYBENZOATE HYDROXYLASE: THE TYR201PHE, TYR385PHE, AND ASN300ASP VARIANTS | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID | Authors: | Lah, M.S, Palfey, B.A, Schreuder, H.A, Ludwig, M.L. | Deposit date: | 1994-09-27 | Release date: | 1995-02-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of mutant Pseudomonas aeruginosa p-hydroxybenzoate hydroxylases: the Tyr201Phe, Tyr385Phe, and Asn300Asp variants. Biochemistry, 33, 1994
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4MCV
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![BU of 4mcv by Molmil](/molmil-images/mine/4mcv) | Star 12 bound to analog-sensitive Src kinase | Descriptor: | (7S)-12-(4-aminobutyl)-7-(2-methylpropyl)-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one, Proto-oncogene tyrosine-protein kinase Src | Authors: | Lopez, M.S, Shokat, K.M. | Deposit date: | 2013-08-21 | Release date: | 2013-11-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology. J.Am.Chem.Soc., 135, 2013
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4LTM
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![BU of 4ltm by Molmil](/molmil-images/mine/4ltm) | Crystal structures of NADH:FMN oxidoreductase (EMOB) - FMN complex | Descriptor: | FLAVIN MONONUCLEOTIDE, NADH-dependent FMN reductase, SULFATE ION | Authors: | Nissen, M.S, Youn, B, Knowles, B.D, Ballinger, J.W, Jun, S, Belchik, S.M, Xun, L, Kang, C. | Deposit date: | 2013-07-23 | Release date: | 2013-08-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Crystal structures of NADH:FMN oxidoreductase (EmoB) at different stages of catalysis. J.Biol.Chem., 283, 2008
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4LZI
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![BU of 4lzi by Molmil](/molmil-images/mine/4lzi) | Characterization of Solanum tuberosum Multicystatin and Significance of Core Domains | Descriptor: | Multicystatin | Authors: | Nissen, M.S, Kumar, G.N, Green, A.R, Knowles, N.R, Kang, C. | Deposit date: | 2013-07-31 | Release date: | 2014-02-26 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Characterization of Solanum tuberosum Multicystatin and the Significance of Core Domains. Plant Cell, 25, 2013
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1SAQ
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![BU of 1saq by Molmil](/molmil-images/mine/1saq) | Crystal Structure of the RNA octamer GIC(GA)GCC | Descriptor: | 5'-R(*GP*IP*CP*GP*AP*GP*CP*C)-3' | Authors: | Jang, S.B, Baeyens, K, Jeong, M.S, SantaLucia Jr, J, Turner, D, Holbrook, S.R. | Deposit date: | 2004-02-09 | Release date: | 2004-05-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structures of two RNA octamers containing tandem G.A base pairs. Acta Crystallogr.,Sect.D, 60, 2004
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1SDQ
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![BU of 1sdq by Molmil](/molmil-images/mine/1sdq) | Structure of reduced-NO adduct of mesopone cytochrome c peroxidase | Descriptor: | Cytochrome c peroxidase, mitochondrial, FE-(4-MESOPORPHYRINONE)-R-ISOMER, ... | Authors: | Bhaskar, B, Immoos, C.E, Sulc, F, Cohem, M.S, Farmer, P.J, Poulos, T.L. | Deposit date: | 2004-02-13 | Release date: | 2005-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Crystal structures of resting (Fe3+), reduced (Fe2+) and NO-bound states of mesopone cytochrome c peroxidase (MpCcP) (R-isomer) To be Published
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1SA9
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![BU of 1sa9 by Molmil](/molmil-images/mine/1sa9) | Crystal Structure of the RNA octamer GGCGAGCC | Descriptor: | 5'-R(*GP*GP*CP*GP*AP*GP*CP*C)-3' | Authors: | Jang, S.B, Baeyens, K, Jeong, M.S, SantaLucia Jr, J, Turner, D, Holbrook, S.R. | Deposit date: | 2004-02-09 | Release date: | 2004-05-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.86 Å) | Cite: | Structures of two RNA octamers containing tandem G.A base pairs. Acta Crystallogr.,Sect.D, 60, 2004
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1U3Q
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![BU of 1u3q by Molmil](/molmil-images/mine/1u3q) | Crystal Structure of Estrogen Receptor beta complexed with CL-272 | Descriptor: | 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL, Estrogen receptor beta | Authors: | Malamas, M.S, Manas, E.S, McDevitt, R.E, Gunawan, I, Xu, Z.B, Collini, M.D, Miller, C.P, Dinh, T, Henderson, R.A, Keith Jr, J.C, Harris, H.A. | Deposit date: | 2004-07-22 | Release date: | 2005-07-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. J.Med.Chem., 47, 2004
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1U3R
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![BU of 1u3r by Molmil](/molmil-images/mine/1u3r) | Crystal Structure of Estrogen Receptor beta complexed with WAY-338 | Descriptor: | 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL, Estrogen receptor beta, steroid receptor coactivator-1 | Authors: | Malamas, M.S, Manas, E.S, McDevitt, R.E, Gunawan, I, Xu, Z.B, Collini, M.D, Miller, C.P, Dinh, T, Henderson, R.A, Keith Jr, J.C, Harris, H.A. | Deposit date: | 2004-07-22 | Release date: | 2005-07-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. J.Med.Chem., 47, 2004
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1U9E
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![BU of 1u9e by Molmil](/molmil-images/mine/1u9e) | CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-397 | Descriptor: | 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL, Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1 | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | Deposit date: | 2004-08-09 | Release date: | 2005-03-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-Based Design Of Estrogen Receptor-beta Selective Ligands J.Am.Chem.Soc., 126, 2004
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1UFI
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![BU of 1ufi by Molmil](/molmil-images/mine/1ufi) | Crystal structure of the dimerization domain of human CENP-B | Descriptor: | Major centromere autoantigen B | Authors: | Tawaramoto, M.S, Kurumizaka, H, Tanaka, Y, Park, S.-Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-05-30 | Release date: | 2004-02-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of the human centromere protein B (CENP-B) dimerization domain at 1.65-A resolution J.Biol.Chem., 278, 2003
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1U3S
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![BU of 1u3s by Molmil](/molmil-images/mine/1u3s) | Crystal Structure of Estrogen Receptor beta complexed with WAY-797 | Descriptor: | 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL, Estrogen receptor beta, steroid receptor coactivator-1 | Authors: | Malamas, M.S, Manas, E.S, McDevitt, R.E, Gunawan, I, Xu, Z.B, Collini, M.D, Miller, C.P, Dinh, T, Henderson, R.A, Keith Jr, J.C, Harris, H.A. | Deposit date: | 2004-07-22 | Release date: | 2005-07-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. J.Med.Chem., 47, 2004
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1U9K
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![BU of 1u9k by Molmil](/molmil-images/mine/1u9k) | |
3KH2
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![BU of 3kh2 by Molmil](/molmil-images/mine/3kh2) | Crystal structure of the P1 bacteriophage Doc toxin (F68S) in complex with the Phd antitoxin (L17M/V39A). Northeast Structural Genomics targets ER385-ER386 | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Death on curing protein, ... | Authors: | Arbing, M.A, Kuzin, A.P, Su, M, Abashidze, M, Verdon, G, Liu, M, Xiao, R, Acton, T, Inouye, M, Montelione, G.T, Woychik, N.A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2009-10-29 | Release date: | 2010-08-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems. Structure, 18, 2010
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8CCU
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![BU of 8ccu by Molmil](/molmil-images/mine/8ccu) | Cathepsin B1 from Schistosoma mansoni in complex with gallinamide analog 1 | Descriptor: | Cathepsin B-like peptidase (C01 family), SODIUM ION, [(2~{S})-1-[[(2~{S})-1-[[(2~{S})-5-[(2~{S})-3-methoxy-2-(2-methylpropyl)-5-oxidanylidene-2~{H}-pyrrol-1-yl]-5-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl] (2~{S},3~{S})-2-(dimethylamino)-3-methyl-pentanoate | Authors: | Rubesova, P, Brynda, J, Gerwick, W.H, Mares, M. | Deposit date: | 2023-01-27 | Release date: | 2024-02-07 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis. Acs Infect Dis., 10, 2024
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6LTO
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![BU of 6lto by Molmil](/molmil-images/mine/6lto) | cryo-EM structure of full length human Pannexin1 | Descriptor: | Pannexin-1 | Authors: | Mou, L.Q, Ke, M, Xiao, Q.J, Wu, J.P, Deng, D. | Deposit date: | 2020-01-23 | Release date: | 2020-05-13 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for gating mechanism of Pannexin 1 channel. Cell Res., 30, 2020
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8CC2
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![BU of 8cc2 by Molmil](/molmil-images/mine/8cc2) | Cathepsin B1 from Schistosoma mansoni in complex with gallinamide A | Descriptor: | Cathepsin B-like peptidase (C01 family), SODIUM ION, gallinamide A, ... | Authors: | Rubesova, P, Brynda, J, Mares, M, Gerwick, W.H. | Deposit date: | 2023-01-26 | Release date: | 2024-02-07 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the Cathepsin B1 Protease Target and Binding Mode Analysis. Acs Infect Dis., 10, 2024
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