4AZR
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![BU of 4azr by Molmil](/molmil-images/mine/4azr) | Human epidermal fatty acid-binding protein (FABP5) in complex with the endocannabinoid anandamide | Descriptor: | CHLORIDE ION, FATTY ACID-BINDING PROTEIN, EPIDERMAL, ... | Authors: | Sanson, B, Wang, T, Sun, J, Kaczocha, M, Ojima, I, Deutsch, D, Li, H. | Deposit date: | 2012-06-26 | Release date: | 2013-08-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystallographic Study of Fabp5 as an Intracellular Endocannabinoid Transporter. Acta Crystallogr.,Sect.D, 70, 2014
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4B17
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![BU of 4b17 by Molmil](/molmil-images/mine/4b17) | Crystal structure of C2498 2'-O-ribose methyltransferase RlmM from Escherichia coli in complex with S-adenosylmethionine | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE M, ... | Authors: | Punekar, A.S, Shepherd, T.R, Liljeruhm, J, Forster, A.C, Selmer, M. | Deposit date: | 2012-07-07 | Release date: | 2012-08-15 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Rlmm, the 2'O-Ribose Methyltransferase for C2498 of Escherichia Coli 23S Rrna. Nucleic Acids Res., 40, 2012
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8BB8
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![BU of 8bb8 by Molmil](/molmil-images/mine/8bb8) | |
4B4L
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![BU of 4b4l by Molmil](/molmil-images/mine/4b4l) | CRYSTAL STRUCTURE OF AN ARD DAP-KINASE 1 MUTANT | Descriptor: | DEATH-ASSOCIATED PROTEIN KINASE 1, PENTAETHYLENE GLYCOL, SULFATE ION | Authors: | Temmerman, K, Pogenberg, V, Jonko, W, Wilmanns, M. | Deposit date: | 2012-07-31 | Release date: | 2013-08-21 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | A Pef/Y Substrate Recognition and Signature Motif Plays a Critical Role in Dapk-Related Kinase Activity. Chem.Biol., 21, 2014
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2M12
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![BU of 2m12 by Molmil](/molmil-images/mine/2m12) | |
3GZD
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![BU of 3gzd by Molmil](/molmil-images/mine/3gzd) | Human selenocysteine lyase, P1 crystal form | Descriptor: | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, NITRATE ION, Selenocysteine lyase | Authors: | Karlberg, T, Hogbom, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2009-04-07 | Release date: | 2009-04-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase. Plos One, 7, 2012
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2M06
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![BU of 2m06 by Molmil](/molmil-images/mine/2m06) | NMR structure of OmpX in phopspholipid nanodiscs | Descriptor: | Outer membrane protein X | Authors: | Hagn, F.X, Etzkorn, M, Raschle, T, Wagner, G, Membrane Protein Structures by Solution NMR (MPSbyNMR) | Deposit date: | 2012-10-21 | Release date: | 2012-12-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins. J.Am.Chem.Soc., 135, 2013
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4B3P
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![BU of 4b3p by Molmil](/molmil-images/mine/4b3p) | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | Descriptor: | DNA, P51 RT, REVERSE TRANSCRIPTASE/RIBONUCLEASE H, ... | Authors: | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | Deposit date: | 2012-07-25 | Release date: | 2013-01-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.839 Å) | Cite: | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation Nat.Struct.Mol.Biol., 20, 2013
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8BPR
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![BU of 8bpr by Molmil](/molmil-images/mine/8bpr) | Complex of RecF-RecO-RecR-DNA from Thermus thermophilus (low resolution reconstruction). | Descriptor: | DNA repair protein RecO, DNA replication and repair protein RecF, MAGNESIUM ION, ... | Authors: | Nirwal, S, Czarnocki-Cieciura, M, Chaudhary, A, Zajko, W, Skowronek, K, Chamera, S, Figiel, M, Nowotny, M. | Deposit date: | 2022-11-17 | Release date: | 2023-04-26 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Mechanism of RecF-RecO-RecR cooperation in bacterial homologous recombination. Nat.Struct.Mol.Biol., 30, 2023
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4BCD
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![BU of 4bcd by Molmil](/molmil-images/mine/4bcd) | PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN WITH A NON-COVALENTLY BOUND P2-substituted N-acyl-prolylpyrrolidine inhibitor | Descriptor: | 1-[(2S,4S)-4-[4-(4-fluorophenyl)-1,2,3-triazol-1-yl]-2-pyrrolidin-1-ylcarbonyl-pyrrolidin-1-yl]-4-phenyl-butan-1-one, GLYCEROL, PROLYL ENDOPEPTIDASE, ... | Authors: | VanDerVeken, P, Fulop, V, Rea, D, Gerard, M, VanElzen, R, Joossens, J, Cheng, J.D, Baekelandt, V, DeMeester, I, Lambeir, A.M, Augustyns, K. | Deposit date: | 2012-10-01 | Release date: | 2013-03-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | P2-Substituted N-Acylprolylpyrrolidine Inhibitors of Prolyl Oligopeptidase: Biochemical Evaluation, Binding Mode Determination, and Assessment in a Cellular Model of Synucleinopathy. J.Med.Chem., 55, 2012
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2JBY
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![BU of 2jby by Molmil](/molmil-images/mine/2jby) | A viral protein unexpectedly mimics the structure and function of pro- survival Bcl-2 | Descriptor: | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER 2, M11L PROTEIN, SODIUM ION | Authors: | Kvansakul, M, Van Delft, M.F, Lee, E.F, Gulbis, J.M, Fairlie, W.D, Huang, D.C.S, Colman, P.M. | Deposit date: | 2006-12-14 | Release date: | 2007-03-27 | Last modified: | 2018-06-13 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak. Mol. Cell, 25, 2007
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4B67
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![BU of 4b67 by Molmil](/molmil-images/mine/4b67) | A. fumigatus ornithine hydroxylase (SidA), re-oxidised state bound to NADP and ornithine | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ... | Authors: | Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A. | Deposit date: | 2012-08-09 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases. Biochemistry, 51, 2012
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8BI3
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![BU of 8bi3 by Molmil](/molmil-images/mine/8bi3) | Structure of E. coli Class 2 L-asparaginase EcAIII, mutant M200W (crystal M200W#1) | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Sciuk, A, Ruszkowski, M, Jaskolski, M, Loch, J.I. | Deposit date: | 2022-11-01 | Release date: | 2023-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.452 Å) | Cite: | The effects of nature-inspired amino acid substitutions on structural and biochemical properties of the E. coli L-asparaginase EcAIII. Protein Sci., 32, 2023
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8BKF
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![BU of 8bkf by Molmil](/molmil-images/mine/8bkf) | Structure of E. coli Class 2 L-asparaginase EcAIII, mutant M200T (crystal M200T#o) | Descriptor: | CHLORIDE ION, Isoaspartyl peptidase subunit alpha, Isoaspartyl peptidase subunit beta, ... | Authors: | Sciuk, A, Ruszkowski, M, Jaskolski, M, Loch, J.I. | Deposit date: | 2022-11-09 | Release date: | 2023-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.221 Å) | Cite: | The effects of nature-inspired amino acid substitutions on structural and biochemical properties of the E. coli L-asparaginase EcAIII. Protein Sci., 32, 2023
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4AXW
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![BU of 4axw by Molmil](/molmil-images/mine/4axw) | CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 AND PROTOCADHERIN-15 EC1- 2, FORM I 2.2A. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CADHERIN-23, CALCIUM ION, ... | Authors: | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | Deposit date: | 2012-06-14 | Release date: | 2012-11-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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4BDI
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![BU of 4bdi by Molmil](/molmil-images/mine/4bdi) | Fragment-based screening identifies a new area for inhibitor binding to checkpoint kinase 2 (CHK2) | Descriptor: | 1,2-ETHANEDIOL, 1-acetyl-N-(5-methylpyridin-2-yl)piperidine-4-carboxamide, CHLORIDE ION, ... | Authors: | Silva-Santisteban, M.C, Westwood, I.M, Boxall, K, Brown, N, Peacock, S, McAndrew, C, Barrie, E, Richards, M, Mirza, A, Oliver, A.W, Burke, R, Hoelder, S, Jones, K, Aherne, G.W, Blagg, J, Collins, I, Garrett, M.D, van Montfort, R.L.M. | Deposit date: | 2012-10-05 | Release date: | 2013-06-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2. Plos One, 8, 2013
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2RQE
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![BU of 2rqe by Molmil](/molmil-images/mine/2rqe) | Solution structure of the silkworm bGRP/GNBP3 N-terminal domain reveals the mechanism for b-1,3-glucan specific recognition | Descriptor: | Beta-1,3-glucan-binding protein | Authors: | Takahasi, K, Ochiai, M, Horiuchi, M, Kumeta, H, Ogura, K, Ashida, M, Inagaki, F. | Deposit date: | 2009-04-22 | Release date: | 2009-06-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the silkworm betaGRP/GNBP3 N-terminal domain reveals the mechanism for beta-1,3-glucan-specific recognition. Proc.Natl.Acad.Sci.USA, 106, 2009
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8BP9
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![BU of 8bp9 by Molmil](/molmil-images/mine/8bp9) | Structure of E. coli Class 2 L-asparaginase EcAIII, mutant M200W (crystal M200W#2) | Descriptor: | CHLORIDE ION, Isoaspartyl peptidase subunit alpha, Isoaspartyl peptidase subunit beta, ... | Authors: | Sciuk, A, Jaskolski, M, Loch, J.I. | Deposit date: | 2022-11-16 | Release date: | 2023-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The effects of nature-inspired amino acid substitutions on structural and biochemical properties of the E. coli L-asparaginase EcAIII. Protein Sci., 32, 2023
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2JTI
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![BU of 2jti by Molmil](/molmil-images/mine/2jti) | |
2JUS
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4B3O
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![BU of 4b3o by Molmil](/molmil-images/mine/4b3o) | Structures of HIV-1 RT and RNA-DNA Complex Reveal a Unique RT Conformation and Substrate Interface | Descriptor: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, 5'-D(*CP*GP*TP*AP*TP*GP*CP*CP*TP*AP*TP*AP*GP*TP *TP*AP*TP*TP*GP*TP*GP*GP*CP*C)-3', 5'-R(*AP*UP*GP*AP*3DRP*GP*GP*CP*CP*AP*CP*AP*AP*UP*AP *AP*CP*UP*AP*UP*AP*GP*GP*CP*AP*UP*A)-3', ... | Authors: | Lapkouski, M, Tian, L, Miller, J.T, Le Grice, S.F.J, Yang, W. | Deposit date: | 2012-07-25 | Release date: | 2013-01-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Complexes of HIV-1 RT, Nnrti and RNA/DNA Hybrid Reveal a Structure Compatible with RNA Degradation Nat.Struct.Mol.Biol., 20, 2013
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4B41
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![BU of 4b41 by Molmil](/molmil-images/mine/4b41) | Crystal structure of an amyloid-beta binding single chain antibody G7 | Descriptor: | ANTIBODY G7, CHLORIDE ION, GLYCEROL | Authors: | Beringer, D.X, Dorresteijn, B, Rutten, L, Wienk, H, el Khattabi, M, Kroon-Batenburg, L.M.J, Verrips, C.T. | Deposit date: | 2012-07-27 | Release date: | 2013-08-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.191 Å) | Cite: | Crystal Structure of an Amyloid-Beta Binding Single Chain Antibody G7 To be Published
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4B65
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![BU of 4b65 by Molmil](/molmil-images/mine/4b65) | A. fumigatus ornithine hydroxylase (SidA), reduced state bound to NADP(H) | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, L-ORNITHINE N5 MONOOXYGENASE, ... | Authors: | Franceschini, S, Fedkenheuer, M, Vogelaar, N.J, Robinson, H.H, Sobrado, P, Mattevi, A. | Deposit date: | 2012-08-09 | Release date: | 2012-10-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Structural Insight Into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases. Biochemistry, 51, 2012
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4YUK
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![BU of 4yuk by Molmil](/molmil-images/mine/4yuk) | Multiconformer synchrotron model of CypA at 260 K | Descriptor: | Peptidyl-prolyl cis-trans isomerase A | Authors: | Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S. | Deposit date: | 2015-03-18 | Release date: | 2015-10-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography. Elife, 4, 2015
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2JYA
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![BU of 2jya by Molmil](/molmil-images/mine/2jya) | NMR solution structure of protein ATU1810 from Agrobacterium tumefaciens. Northeast Structural Genomics Consortium target AtR23, Ontario Centre for Structural Proteomics Target ATC1776 | Descriptor: | Uncharacterized protein Atu1810 | Authors: | Lemak, A, Yee, A, Gutmanas, A, Fares, C, Karra, M, Semesi, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2007-12-07 | Release date: | 2007-12-25 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of protein ATU1810 form Agrobacterium tumefaciens. To be Published
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