3N2K
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![BU of 3n2k by Molmil](/molmil-images/mine/3n2k) | TUBULIN-NSC 613862: RB3 Stathmin-like domain complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Barbier, P, Dorleans, A, Devred, F, Sanz, L, Allegro, D, Alfonso, C, Knossow, M, Peyrot, V, Andreu, J.M. | Deposit date: | 2010-05-18 | Release date: | 2010-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Stathmin and interfacial microtubule inhibitors recognize a naturally curved conformation of tubulin dimers. J.Biol.Chem., 285, 2010
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8AMU
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![BU of 8amu by Molmil](/molmil-images/mine/8amu) | RepB pMV158 OBD domain bound to DDR region | Descriptor: | DNA (5'-D(*AP*AP*AP*AP*GP*TP*CP*GP*CP*CP*GP*AP*AP*AP*AP*GP*TP*CP*GP*CP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*GP*CP*GP*AP*CP*TP*TP*TP*TP*CP*GP*GP*CP*GP*AP*CP*TP*TP*TP*T)-3'), MANGANESE (II) ION, ... | Authors: | Amodio, J, Machon, C, Boer, R.D, Ruiz-Maso, J.A, del Solar, G, Coll, M. | Deposit date: | 2022-08-04 | Release date: | 2023-02-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of pMV158 replication initiator RepB with and without DNA reveal a flexible dual-function protein. Nucleic Acids Res., 51, 2023
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1KR6
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6G51
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![BU of 6g51 by Molmil](/molmil-images/mine/6g51) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State D | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | Authors: | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | Deposit date: | 2018-03-28 | Release date: | 2018-06-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
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1KH1
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![BU of 1kh1 by Molmil](/molmil-images/mine/1kh1) | |
6G71
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![BU of 6g71 by Molmil](/molmil-images/mine/6g71) | Structure of CYP1232A24 from Arthrobacter sp. | Descriptor: | 1,2-ETHANEDIOL, Cytochrome P450, FE (III) ION, ... | Authors: | Dubiel, P, Sharma, M, Klenk, J, Hauer, B, Grogan, G. | Deposit date: | 2018-04-04 | Release date: | 2019-03-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine. J.Biochem., 166, 2019
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6G8A
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![BU of 6g8a by Molmil](/molmil-images/mine/6g8a) | Lysozyme solved by Native SAD from a dataset collected in 5 seconds at 1 A wavelength with JUNGFRAU detector | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | Authors: | Leonarski, F, Olieric, V, Vera, L, Redford, S, Wang, M. | Deposit date: | 2018-04-08 | Release date: | 2018-08-01 | Last modified: | 2018-10-24 | Method: | X-RAY DIFFRACTION (1.143 Å) | Cite: | Fast and accurate data collection for macromolecular crystallography using the JUNGFRAU detector. Nat. Methods, 15, 2018
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5BUN
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![BU of 5bun by Molmil](/molmil-images/mine/5bun) | Crystal structure of an antigenic outer membrane protein ST50 from Salmonella Typhi | Descriptor: | Outer membrane protein, octyl beta-D-glucopyranoside | Authors: | Yoshimura, M, Chuankhayan, P, Lin, C.C, Chen, N.C, Yang, M.C, Fun, H.K. | Deposit date: | 2015-06-04 | Release date: | 2015-12-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Crystal structure of an antigenic outer-membrane protein from Salmonella Typhi suggests a potential antigenic loop and an efflux mechanism. Sci Rep, 5, 2015
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6G9L
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![BU of 6g9l by Molmil](/molmil-images/mine/6g9l) | Structure of homomeric mLRRC8A volume-regulated anion channel at 5.01 A resolution | Descriptor: | Volume-regulated anion channel subunit LRRC8A | Authors: | Sawicka, M, Deneka, D, Lam, A.K.M, Paulino, C, Dutzler, R. | Deposit date: | 2018-04-11 | Release date: | 2018-05-16 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (5.01 Å) | Cite: | Structure of a volume-regulated anion channel of the LRRC8 family. Nature, 558, 2018
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5AM7
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![BU of 5am7 by Molmil](/molmil-images/mine/5am7) | FGFR1 mutant with an inhibitor | Descriptor: | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, CHLORIDE ION, FIBROBLAST GROWTH FACTOR RECEPTOR 1 | Authors: | Bunney, T.D, Wan, S, Thiyagarajan, N, Sutto, L, Williams, S.V, Ashford, P, Koss, H, Knowles, M.A, Gervasio, F.L, Coveney, P.V, Katan, M. | Deposit date: | 2015-03-10 | Release date: | 2015-03-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.957 Å) | Cite: | The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study Ebiomedicine, 2, 2015
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8ABW
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![BU of 8abw by Molmil](/molmil-images/mine/8abw) | Crystal structure of SpLdpA in complex with threo-DGPD | Descriptor: | (1R,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, (1S,2S)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, SULFATE ION, ... | Authors: | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | Deposit date: | 2022-07-04 | Release date: | 2023-02-01 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation. Proc.Natl.Acad.Sci.USA, 120, 2023
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5AOQ
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![BU of 5aoq by Molmil](/molmil-images/mine/5aoq) | Structural basis of neurohormone perception by the receptor tyrosine kinase Torso | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PREPROPTTH, TORSO | Authors: | Jenni, S, Goyal, Y, von Grotthuss, M, Shvartsman, S.Y, Klein, D.E. | Deposit date: | 2015-09-11 | Release date: | 2015-11-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis of Neurohormone Perception by the Receptor Tyrosine Kinase Torso. Mol.Cell, 60, 2015
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4MR8
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![BU of 4mr8 by Molmil](/molmil-images/mine/4mr8) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the antagonist CGP35348 | Descriptor: | (S)-(3-aminopropyl)(diethoxymethyl)phosphinic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-17 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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1L1P
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![BU of 1l1p by Molmil](/molmil-images/mine/1l1p) | Solution Structure of the PPIase Domain from E. coli Trigger Factor | Descriptor: | trigger factor | Authors: | Kozlov, G, Trempe, J.-F, Perreault, A, Wong, M, Denisov, A, Ghandi, S, Gehring, K, Ekiel, I, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2002-02-19 | Release date: | 2003-06-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Closed Form of a Peptidyl-Prolyl Isomerase Reveals the Mechanism of Protein Folding To be Published
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4MS3
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![BU of 4ms3 by Molmil](/molmil-images/mine/4ms3) | Crystal structure of the extracellular domain of human GABA(B) receptor bound to the endogenous agonist GABA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, Gamma-aminobutyric acid type B receptor subunit 1, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-18 | Release date: | 2013-12-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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3N73
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![BU of 3n73 by Molmil](/molmil-images/mine/3n73) | Crystal structure of a putative 4-hydroxy-2-oxoglutarate aldolase from Bacillus cereus | Descriptor: | CHLORIDE ION, Putative 4-hydroxy-2-oxoglutarate aldolase | Authors: | Cabello, R, Chruszcz, M, Xu, X, Zimmerman, M.D, Cui, H, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-05-26 | Release date: | 2010-06-09 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Crystal structure of a putative 4-hydroxy-2-oxoglutarate aldolase from Bacillus cereus To be Published
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6GAZ
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![BU of 6gaz by Molmil](/molmil-images/mine/6gaz) | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the 28S ribosomal subunit. | Descriptor: | 12S ribosomal RNA, mitochondrial, 28S ribosomal protein S18b, ... | Authors: | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | Deposit date: | 2018-04-13 | Release date: | 2018-08-08 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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4MJI
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![BU of 4mji by Molmil](/molmil-images/mine/4mji) | T cell response to a HIV reverse transcriptase epitope presented by the protective allele HLA-B*51:01 | Descriptor: | Beta-2-microglobulin, HIV Reverse Transcriptase peptide Marker, HLA class I histocompatibility antigen, ... | Authors: | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Motozono, C, Takiguchi, M. | Deposit date: | 2013-09-03 | Release date: | 2014-05-28 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Molecular basis of a dominant T cell response to an HIV reverse transcriptase 8-mer epitope presented by the protective allele HLA-B*51:01 J.Immunol., 192, 2014
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6GAW
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![BU of 6gaw by Molmil](/molmil-images/mine/6gaw) | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. This file contains the complete 55S ribosome. | Descriptor: | 12S ribosomal RNA, mitochondrial, 16S ribosomal RNA, ... | Authors: | Kummer, E, Leibundgut, M, Boehringer, D, Ban, N. | Deposit date: | 2018-04-13 | Release date: | 2018-08-22 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM. Nature, 560, 2018
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5AV4
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6K7J
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![BU of 6k7j by Molmil](/molmil-images/mine/6k7j) | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1-ATP state class1) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ... | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2019-06-07 | Release date: | 2019-08-28 | Last modified: | 2021-02-10 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365, 2019
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6K7Y
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![BU of 6k7y by Molmil](/molmil-images/mine/6k7y) | Intact human mitochondrial calcium uniporter complex with MICU1/MICU2 subunits | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, CARDIOLIPIN, ... | Authors: | Zhuo, W, Zhou, H, Yang, M. | Deposit date: | 2019-06-10 | Release date: | 2020-09-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of intact human MCU supercomplex with the auxiliary MICU subunits. Protein Cell, 12, 2021
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3MZZ
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![BU of 3mzz by Molmil](/molmil-images/mine/3mzz) | Crystal Structure of Rhodanese-like Domain Protein from Staphylococcus aureus | Descriptor: | Rhodanese-like domain protein | Authors: | Kim, Y, Chruszcz, M, Minor, W, Edwards, A, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2010-05-13 | Release date: | 2010-06-30 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Rhodanese-like Domain Protein from Staphylococcus aureus To be Published
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5AQA
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![BU of 5aqa by Molmil](/molmil-images/mine/5aqa) | DARPin-based Crystallization Chaperones exploit Molecular Geometry as a Screening Dimension in Protein Crystallography | Descriptor: | OFF7_DB04V3, THIOCYANATE ION | Authors: | Batyuk, A, Wu, Y, Honegger, A, Heberling, M, Plueckthun, A. | Deposit date: | 2015-09-21 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography J.Mol.Biol., 428, 2016
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6FVQ
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![BU of 6fvq by Molmil](/molmil-images/mine/6fvq) | |