4MQE
| Crystal structure of the extracellular domain of human GABA(B) receptor in the apo form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, ... | Authors: | Geng, Y, Bush, M, Mosyak, L, Wang, F, Fan, Q.R. | Deposit date: | 2013-09-16 | Release date: | 2013-12-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural mechanism of ligand activation in human GABA(B) receptor. Nature, 504, 2013
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1IXX
| CRYSTAL STRUCTURE OF COAGULATION FACTORS IX/X-BINDING PROTEIN (IX/X-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS | Descriptor: | CALCIUM ION, COAGULATION FACTORS IX/X-BINDING PROTEIN | Authors: | Mizuno, H, Fujimoto, Z, Koizumi, M, Kano, H. | Deposit date: | 1997-05-01 | Release date: | 1998-05-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of coagulation factors IX/X-binding protein, a heterodimer of C-type lectin domains. Nat.Struct.Biol., 4, 1997
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4L7N
| Human artd3 (parp3) - catalytic domain in complex with inhibitor STO1542 | Descriptor: | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-(4-sulfamoylphenyl)ethyl]propanamide, Poly [ADP-ribose] polymerase 3 | Authors: | Karlberg, T, Thorsell, A.G, Lindgren, A.E.G, Ekblad, T, Spjut, S, Andersson, C.D, Weigelt, J, Linusson, A, Elofsson, M, Schuler, H. | Deposit date: | 2013-06-14 | Release date: | 2014-02-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3. J.Med.Chem., 56, 2013
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3AUL
| Crystal structure of wild-type Lys48-linked diubiquitin in an open conformation | Descriptor: | Polyubiquitin-C | Authors: | Hirano, T, Olivier, S, Yagi, M, Takemoto, E, Hiromoto, T, Satoh, T, Mizushima, T, Kato, K. | Deposit date: | 2011-02-09 | Release date: | 2011-09-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Conformational dynamics of wild-type Lys48-linked diubiquitin in solution J.Biol.Chem., 286, 2011
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4N1J
| Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | Descriptor: | GLYCEROL, NACHT, LRR and PYD domains-containing protein 14 | Authors: | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | Deposit date: | 2013-10-04 | Release date: | 2014-07-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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6E6M
| Crystal structure of human cellular retinol-binding protein 1 in complex with cannabidiorcin (CBDO) | Descriptor: | (1'R,2'R)-4,5'-dimethyl-2'-(prop-1-en-2-yl)-1',2',3',4'-tetrahydro[1,1'-biphenyl]-2,6-diol, Retinol-binding protein 1 | Authors: | Silvaroli, J.A, Horwitz, S, Banerjee, S, Kiser, P.D, Golczak, M. | Deposit date: | 2018-07-25 | Release date: | 2019-02-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1. Acs Chem.Biol., 14, 2019
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1IZK
| Thermoactinomyces vulgaris R-47 alpha-amylase 1 mutant enzyme w398v | Descriptor: | CALCIUM ION, amylase | Authors: | Ohtaki, A, Iguchi, A, Mizuno, M, Tonozuka, T, Sakano, Y, Kamitori, S. | Deposit date: | 2002-10-03 | Release date: | 2003-07-29 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Mutual conversion of substrate specificities of Thermoactinomyces vulgaris R-47 alpha-amylases TVAI and TVAII by site-directed mutagenesis CARBOHYDR.RES., 338, 2003
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6TTC
| Haddock model of NDM-1/myricetin complex | Descriptor: | 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, Metallo beta lactamase NDM-1, ZINC ION | Authors: | Riviere, G, Oueslati, S, Gayral, M, Crechet, J.B, Nhiri, N, Jacquet, E, Cintrat, J.C, Giraud, F, van Heijenoort, C, Lescop, E, Pethe, S, Iorga, B.I, Naas, T, Guittet, E, Morellet, N. | Deposit date: | 2019-12-26 | Release date: | 2021-01-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Characterization of the Influence of Zinc(II) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-beta-Lactamase-1 and on the Binding with Flavonols as Inhibitors. Acs Omega, 5, 2020
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1IPE
| TROPINONE REDUCTASE-II COMPLEXED WITH NADPH | Descriptor: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TROPINONE REDUCTASE-II | Authors: | Yamashita, A, Endo, M, Higashi, T, Nakatsu, T, Yamada, Y, Oda, J, Kato, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-05-09 | Release date: | 2003-06-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Capturing Enzyme Structure Prior to Reaction Initiation: Tropinone Reductase-II-Substrate Complexes BIOCHEMISTRY, 42, 2003
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1IQ7
| Ovotransferrin, C-Terminal Lobe, Apo Form | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Ovotransferrin, SULFATE ION | Authors: | Mizutani, K, Muralidhara, B.K, Yamashita, H, Tabata, S, Mikami, B, Hirose, M. | Deposit date: | 2001-07-06 | Release date: | 2001-11-28 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Anion-mediated Fe3+ release mechanism in ovotransferrin C-lobe: a structurally identified SO4(2-) binding site and its implications for the kinetic pathway. J.Biol.Chem., 276, 2001
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4N2B
| Crystal structure of Protein Arginine Deiminase 2 (10 mM Ca2+) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Protein-arginine deiminase type-2 | Authors: | Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R. | Deposit date: | 2013-10-04 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chem.Biol., 10, 2015
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6HXY
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1IQD
| Human Factor VIII C2 Domain complexed to human monoclonal BO2C11 Fab. | Descriptor: | HUMAN FACTOR VIII, HUMAN MONOCLONAL BO2C11 FAB HEAVY CHAIN, HUMAN MONOCLONAL BO2C11 FAB LIGHT CHAIN | Authors: | Spiegel Jr, P.C, Jacquemin, M, Saint-Remy, J.M, Stoddard, B.L, Pratt, K.P. | Deposit date: | 2001-07-21 | Release date: | 2001-08-15 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of a factor VIII C2 domain-immunoglobulin G4kappa Fab complex: identification of an inhibitory antibody epitope on the surface of factor VIII. Blood, 98, 2001
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6HY5
| THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Q193C | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Hu, H.D, Delarue, M. | Deposit date: | 2018-10-19 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4IH2
| Crystal structure of kirola (Act d 11) from crystal soaked with 2-aminopurine | Descriptor: | CHLORIDE ION, Kirola, UNKNOWN LIGAND | Authors: | Chruszcz, M, Ciardiello, M.A, Giangrieco, I, Osinski, T, Minor, W. | Deposit date: | 2012-12-18 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural and bioinformatic analysis of the kiwifruit allergen Act d 11, a member of the family of ripening-related proteins. Mol.Immunol., 56, 2013
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6TQZ
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3ESC
| cut-2a; NCN-Pt-Pincer-Cutinase Hybrid | Descriptor: | Cutinase 1, bromo(4-{3-[(R)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}-2,6-bis[(methylsulfanyl-kappaS)methyl]phenyl-kappaC~1~)palladium(2+) | Authors: | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | Deposit date: | 2008-10-05 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids Chemistry, 15, 2009
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4IHP
| Crystal structure of TgCDPK1 with inhibitor bound | Descriptor: | 1-tert-butyl-3-(3-chlorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1, UNKNOWN ATOM OR ION | Authors: | El Bakkouri, M, Tempel, W, Crandall, I.E, Massad, T, Loppnau, P, Graslund, S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Kain, C.K, Shokat, K.M, Sibley, L.D, Hui, R, Structural Genomics Consortium (SGC) | Deposit date: | 2012-12-19 | Release date: | 2014-01-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of TgCDPK1 with inhibitor bound TO BE PUBLISHED
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1IRU
| Crystal Structure of the mammalian 20S proteasome at 2.75 A resolution | Descriptor: | 20S proteasome, MAGNESIUM ION | Authors: | Unno, M, Mizushima, T, Morimoto, Y, Tomisugi, Y, Tanaka, K, Yasuoka, N, Tsukihara, T. | Deposit date: | 2001-10-24 | Release date: | 2002-05-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | The structure of the mammalian 20S proteasome at 2.75 A resolution. Structure, 10, 2002
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6HYV
| THE GLIC PENTAMERIC LIGAND-GATED ION CHANNEL MUTANT Y119A | Descriptor: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | Authors: | Hu, H.D, Delarue, M. | Deposit date: | 2018-10-22 | Release date: | 2018-12-19 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E2B
| Ubiquitin in complex with Pt(2-phenilpyridine)(PPh3) | Descriptor: | GLYCEROL, SULFATE ION, Ubiquitin, ... | Authors: | Zhemkov, V.A, Kim, M. | Deposit date: | 2018-07-11 | Release date: | 2018-11-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Reactions of Cyclometalated Platinum(II) [Pt(N∧C)(PR3)Cl] Complexes with Imidazole and Imidazole-Containing Biomolecules: Fine-Tuning of Reactivity and Photophysical Properties via Ligand Design. Inorg Chem, 58, 2019
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3ESA
| cut-1b; NCN-Pt-Pincer-Cutinase Hybrid | Descriptor: | (2,6-bis[(dimethylamino-kappaN)methyl]-4-{3-[(S)-ethoxy(4-nitrophenoxy)phosphoryl]propyl}phenyl-kappaC~1~)(chloro)platinum(2+), Cutinase 1 | Authors: | Rutten, L, Mannie, J.P.B.A, Lutz, M, Gros, P. | Deposit date: | 2008-10-05 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Solid-state structural characterization of cutinase-ECE-pincer-metal hybrids Chemistry, 15, 2009
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6TPS
| early intermediate RNA Polymerase I Pre-initiation complex - eiPIC | Descriptor: | DNA foreign, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, ... | Authors: | Pilsl, M, Engel, C. | Deposit date: | 2019-12-14 | Release date: | 2020-03-18 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting. Nat Commun, 11, 2020
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1IST
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6TRH
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