2M40
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m40 by Molmil](/molmil-images/mine/2m40) | DNA containing a cluster of 8-oxo-guanine and THF lesion | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*CP*(3DR)P*CP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*TP*GP*GP*GP*AP*(8OG)P*CP*G)-3') | Authors: | Zalesak, J, Jourdan, M, Constant, J, Lourdin, M. | Deposit date: | 2013-01-28 | Release date: | 2014-01-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and dynamics of DNA duplexes containing a cluster of mutagenic 8-oxoguanine and abasic site lesions. J.Mol.Biol., 426, 2014
|
|
2MMT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mmt by Molmil](/molmil-images/mine/2mmt) | Lasso peptide-based integrin inhibitor: Microcin J25 variant with RGDF substitution of Gly12-Ile13-Gly14-Thr15 | Descriptor: | Microcin J25 RGDF mutant | Authors: | Hegemann, J.D, Zimmermann, M, Knappe, T.A, Xie, X, Marahiel, M.A. | Deposit date: | 2014-03-18 | Release date: | 2014-07-02 | Last modified: | 2014-07-23 | Method: | SOLUTION NMR | Cite: | Rational improvement of the affinity and selectivity of integrin binding of grafted lasso peptides. J.Med.Chem., 57, 2014
|
|
2MNG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mng by Molmil](/molmil-images/mine/2mng) | Apo Structure of human HCN4 CNBD solved by NMR | Descriptor: | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | Authors: | Akimoto, M, Zhang, Z, Boulton, S, Selvaratnam, R, VanSchouwen, B, Gloyd, M, Accili, E.A, Lange, O.F, Melacini, G. | Deposit date: | 2014-04-03 | Release date: | 2014-06-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A mechanism for the auto-inhibition of hyperpolarization-activated cyclic nucleotide-gated (HCN) channel opening and its relief by cAMP. J.Biol.Chem., 289, 2014
|
|
2MF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mf0 by Molmil](/molmil-images/mine/2mf0) | Structural basis of the non-coding RNA RsmZ acting as protein sponge: Conformer L of RsmZ(1-72)/RsmE(dimer) 1to3 complex | Descriptor: | Carbon storage regulator homolog, RNA_(72-MER) | Authors: | Duss, O, Michel, E, Yulikov, M, Schubert, M, Jeschke, G, Allain, F.H.-T. | Deposit date: | 2013-10-02 | Release date: | 2014-05-21 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural basis of the non-coding RNA RsmZ acting as a protein sponge. Nature, 509, 2014
|
|
2M4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m4x by Molmil](/molmil-images/mine/2m4x) | |
2M43
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m43 by Molmil](/molmil-images/mine/2m43) | DNA containing a cluster of 8-oxo-guanine and abasic site lesion: alpha anomer (AP6, 8OG 14) | Descriptor: | DNA (5'-D(*CP*GP*CP*TP*CP*(ORP)P*CP*AP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*(8OG)P*TP*GP*GP*GP*AP*GP*CP*G)-3') | Authors: | Zalesak, J, Jourdan, M, Constant, J, Lourdin, M. | Deposit date: | 2013-01-29 | Release date: | 2014-01-08 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and dynamics of DNA duplexes containing a cluster of mutagenic 8-oxoguanine and abasic site lesions. J.Mol.Biol., 426, 2014
|
|
2R2Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r2z by Molmil](/molmil-images/mine/2r2z) | The crystal structure of a hemolysin domain from Enterococcus faecalis V583 | Descriptor: | Hemolysin, ZINC ION | Authors: | Zhang, R, Tan, K, Zhou, M, Bargassa, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2007-08-28 | Release date: | 2007-09-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The crystal structure of a hemolysin domain from Enterococcus faecalis V583. To be Published
|
|
2QGM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qgm by Molmil](/molmil-images/mine/2qgm) | Crystal structure of succinoglycan biosynthesis protein at the resolution 1.7 A. Northeast Structural Genomics Consortium target BcR136. | Descriptor: | Succinoglycan biosynthesis protein | Authors: | Kuzin, A.P, Abashidze, M, Jayaraman, S, Wang, H, Fang, Y, Maglaqui, M, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-06-29 | Release date: | 2007-07-24 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of succinoglycan biosynthesis protein at the resolution 1.7 A. Northeast Structural Genomics Consortium target BcR136. To be Published
|
|
2QJG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qjg by Molmil](/molmil-images/mine/2qjg) | M. jannaschii ADH synthase complexed with F1,6P | Descriptor: | 1,6-DI-O-PHOSPHONO-D-ALLITOL, Putative aldolase MJ0400 | Authors: | Ealick, S.E, Morar, M. | Deposit date: | 2007-07-07 | Release date: | 2007-10-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid synthase, a catalyst in the archaeal pathway for the biosynthesis of aromatic amino acids. Biochemistry, 46, 2007
|
|
2QKS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qks by Molmil](/molmil-images/mine/2qks) | |
2QLP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qlp by Molmil](/molmil-images/mine/2qlp) | |
2QMM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qmm by Molmil](/molmil-images/mine/2qmm) | |
2QNR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qnr by Molmil](/molmil-images/mine/2qnr) | Human septin 2 in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Septin-2, UNKNOWN ATOM OR ION | Authors: | Rabeh, W.M, Nedyalkova, L, Tempel, W, Landry, R, Crombet, L, Kozieradzki, I, Senisterra, G, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2007-07-19 | Release date: | 2007-07-31 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Human septin 2 in complex with GDP. To be Published
|
|
2QO6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qo6 by Molmil](/molmil-images/mine/2qo6) | Crystal structure of the glycine 55 arginine mutant of zebrafish liver bile acid-binding protein complexed with cholic acid | Descriptor: | CHOLIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Capaldi, S, Saccomani, G, Perduca, M, Monaco, H.L. | Deposit date: | 2007-07-20 | Release date: | 2007-07-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A Single Amino Acid Mutation in Zebrafish (Danio rerio) Liver Bile Acid-binding Protein Can Change the Stoichiometry of Ligand Binding. J.Biol.Chem., 282, 2007
|
|
2QH9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qh9 by Molmil](/molmil-images/mine/2qh9) | |
2QDJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qdj by Molmil](/molmil-images/mine/2qdj) | Crystal structure of the Retinoblastoma protein N-domain provides insight into tumor suppression, ligand interaction and holoprotein architecture | Descriptor: | Retinoblastoma-associated protein | Authors: | Hassler, M, Mittnacht, S, Pearl, L.H. | Deposit date: | 2007-06-21 | Release date: | 2008-01-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture. Mol.Cell, 28, 2007
|
|
2QEG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qeg by Molmil](/molmil-images/mine/2qeg) | B-DNA with 7-deaza-dG modification | Descriptor: | DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*(7GU)P*DCP*DG)-3') | Authors: | Wang, F, Li, F, Ganguly, M, Marky, L.A, Gold, B, Egli, M, Stone, M.P. | Deposit date: | 2007-06-25 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. Biochemistry, 47, 2008
|
|
5OY1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5oy1 by Molmil](/molmil-images/mine/5oy1) | |
7P8J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p8j by Molmil](/molmil-images/mine/7p8j) | Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein, ... | Authors: | Scietti, L, Castelli, M, Faravelli, S, Clementi, N, Mancini, N, Forneris, F. | Deposit date: | 2021-07-22 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (6.585 Å) | Cite: | Constrained Evolution of SARS-CoV-2 Spike in Rhinolophus affinis Bats To Be Published
|
|
9AUR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9aur by Molmil](/molmil-images/mine/9aur) | Crystal structure of loop-closed A21 2'-OMe dumbbell RNA bridged by glycine | Descriptor: | Fab BL3-6 heavy chain, Fab BL3-6 light chain, GLYCINE, ... | Authors: | Radakovic, A, Lewicka, A, Todisco, M, Aitken, H.R.M, Weiss, Z, Kim, S, Bannan, A, Piccirilli, J.A, Szostak, J.W. | Deposit date: | 2024-02-29 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
5E3A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e3a by Molmil](/molmil-images/mine/5e3a) | Structure of human DPP3 in complex with opioid peptide leu-enkephalin | Descriptor: | Dipeptidyl peptidase 3, Leu-enkephalin, MAGNESIUM ION, ... | Authors: | Kumar, P, Reithofer, V, Reisinger, M, Pavkov-Keller, T, Wallner, S, Macheroux, P, Gruber, K. | Deposit date: | 2015-10-02 | Release date: | 2016-04-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition. Sci Rep, 6, 2016
|
|
7P8I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p8i by Molmil](/molmil-images/mine/7p8i) | Receptor-binding domain (RBD) of the spike protein of the bat coronavirus RaTG13 virus in complex with the extracellular domain of human angiotensin-converting enzyme 2 (ACE2) - Crystal form 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | Authors: | Scietti, L, Castelli, M, Faravelli, S, Clementi, N, Mancini, N, Forneris, F. | Deposit date: | 2021-07-22 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Evidence of SARS-CoV-2 Direct Evolution in R. affinis Bats Driven by Affinity and Dynamics Optimization of the Spike Protein To Be Published
|
|
9AUS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9aus by Molmil](/molmil-images/mine/9aus) | Crystal structure of loop-closed dumbbell RNA bridged by glycine | Descriptor: | Fab BL3-6 heavy chain, Fab BL3-6 light chain, GLYCINE, ... | Authors: | Radakovic, A, Lewicka, A, Todisco, M, Aitken, H.R.M, Weiss, Z, Kim, S, Bannan, A, Piccirilli, J.A, Szostak, J.W. | Deposit date: | 2024-02-29 | Release date: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
5E4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e4g by Molmil](/molmil-images/mine/5e4g) | Crystal structure of human growth differentiation factor 11 (GDF-11) | Descriptor: | Growth/differentiation factor 11, TETRAETHYLENE GLYCOL | Authors: | Padyana, A.K, Vaidialingam, B, Hayes, D.B, Gupta, P, Franti, M, Farrow, N.A. | Deposit date: | 2015-10-06 | Release date: | 2016-03-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of human GDF11. Acta Crystallogr.,Sect.F, 72, 2016
|
|
8BHX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bhx by Molmil](/molmil-images/mine/8bhx) | |