4AFJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4afj by Molmil](/molmil-images/mine/4afj) | 5-aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors | Descriptor: | 5-(4-METHOXYPHENYL)-N-(PYRIDIN-4-YLMETHYL)-1,3-OXAZOLE-4-CARBOXAMIDE, GLYCEROL, GLYCOGEN SYNTHASE KINASE-3 BETA, ... | Authors: | Gentile, G, Merlo, G, Pozzan, A, Bernasconi, G, Bax, B, Bamborough, P, Bridges, A, Carter, P, Neu, M, Yao, G, Brough, C, Cutler, G, Coffin, A, Belyanskaya, S. | Deposit date: | 2012-01-19 | Release date: | 2012-02-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | 5-Aryl-4-Carboxamide-1,3-Oxazoles: Potent and Selective Gsk-3 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
|
|
2W4L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2w4l by Molmil](/molmil-images/mine/2w4l) | Human dCMP deaminase | Descriptor: | CHLORIDE ION, DEOXYCYTIDYLATE DEAMINASE, ZINC ION | Authors: | Siponen, M.I, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schuler, H, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wikstrom, M, Wisniewska, M, Nordlund, P. | Deposit date: | 2008-11-28 | Release date: | 2009-01-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Crystal Structure of Human Dcmp Deaminase To be Published
|
|
4A1I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a1i by Molmil](/molmil-images/mine/4a1i) | ykud from B.subtilis | Descriptor: | CADMIUM ION, CHLORIDE ION, PUTATIVE L, ... | Authors: | Blaise, M, Fuglsang Midtgaard, S, Roi Midtgaard, S, Boesen, T, Thirup, S. | Deposit date: | 2011-09-15 | Release date: | 2012-09-26 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Structures of Three New Crystal Forms of the Ykud L,D-Transpeptidase from B. Subtilis. To be Published
|
|
2MG5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mg5 by Molmil](/molmil-images/mine/2mg5) | |
2M07
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m07 by Molmil](/molmil-images/mine/2m07) | NMR structure of OmpX in DPC micelles | Descriptor: | Outer membrane protein X | Authors: | Hagn, F.X, Etzkorn, M, Raschle, T, Wagner, G, Membrane Protein Structures by Solution NMR (MPSbyNMR) | Deposit date: | 2012-10-21 | Release date: | 2012-12-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins. J.Am.Chem.Soc., 135, 2013
|
|
2MMB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mmb by Molmil](/molmil-images/mine/2mmb) | |
2M60
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m60 by Molmil](/molmil-images/mine/2m60) | Enterocin 7B | Descriptor: | Enterocin JSB | Authors: | Lohans, C.T, Towle, K.M, Miskolzie, M, McKay, R.T, van Belkum, M.J, McMullen, L.M, Vederas, J.C. | Deposit date: | 2013-03-18 | Release date: | 2013-06-12 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution Structures of the Linear Leaderless Bacteriocins Enterocin 7A and 7B Resemble Carnocyclin A, a Circular Antimicrobial Peptide Biochemistry, 52, 2013
|
|
4G7T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4g7t by Molmil](/molmil-images/mine/4g7t) | Rat Heme Oxygenase-1 in complex with Heme and CO with 1 hr Illumination: Laser on | Descriptor: | CARBON MONOXIDE, FORMIC ACID, Heme oxygenase 1, ... | Authors: | Sugishima, M, Moffat, K, Noguchi, M. | Deposit date: | 2012-07-20 | Release date: | 2012-10-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discrimination between CO and O(2) in heme oxygenase: comparison of static structures and dynamic conformation changes following CO photolysis. Biochemistry, 51, 2012
|
|
2M7Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m7q by Molmil](/molmil-images/mine/2m7q) | Solution structure of TAX1BP1 UBZ1+2 | Descriptor: | Tax1-binding protein 1, ZINC ION | Authors: | Ceregido, M.A, Spinola Amilibia, M, Buts, L, Bravo, J, van Nuland, N.A.J. | Deposit date: | 2013-04-29 | Release date: | 2013-12-04 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The structure of TAX1BP1 UBZ1+2 provides insight into target specificity and adaptability. J.Mol.Biol., 426, 2014
|
|
3ZZU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3zzu by Molmil](/molmil-images/mine/3zzu) | |
4A14
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a14 by Molmil](/molmil-images/mine/4a14) | HUMAN KIF7, A KINESIN INVOLVED IN HEDGEHOG SIGNALLING | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN-LIKE PROTEIN KIF7, MAGNESIUM ION | Authors: | Klejnot, M, Kozielski, F. | Deposit date: | 2011-09-14 | Release date: | 2012-01-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Insights Into Human Kif7, a Kinesin Involved in Hedgehog Signalling. Acta Crystallogr.,Sect.D, 68, 2012
|
|
2M23
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m23 by Molmil](/molmil-images/mine/2m23) | |
2LU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lu0 by Molmil](/molmil-images/mine/2lu0) | NMR solution structure of the kappa-zeta region of S.cerevisiae group II intron ai5(gamma) | Descriptor: | RNA (49-MER) | Authors: | Donghi, D, Pechlaner, M, Finazzo, C, Knobloch, B, Sigel, R.K.O. | Deposit date: | 2012-06-05 | Release date: | 2013-04-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The structural stabilization of the kappa three-way junction by Mg(II) represents the first step in the folding of a group II intron. Nucleic Acids Res., 41, 2013
|
|
2ME3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2me3 by Molmil](/molmil-images/mine/2me3) | HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | Descriptor: | Envelope glycoprotein gp160 | Authors: | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | Deposit date: | 2013-09-20 | Release date: | 2013-10-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41. J.Mol.Biol., 426, 2014
|
|
8AX9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ax9 by Molmil](/molmil-images/mine/8ax9) | |
2M58
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m58 by Molmil](/molmil-images/mine/2m58) | Structure of 2'-5' AG1 lariat forming ribozyme in its inactive state | Descriptor: | RNA (59-MER) | Authors: | Carlomagno, T, Amata, I, Codutti, L, Falb, M, Fohrer, J, Simon, B. | Deposit date: | 2013-02-18 | Release date: | 2013-04-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme. J.Am.Chem.Soc., 135, 2013
|
|
4A6P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4a6p by Molmil](/molmil-images/mine/4a6p) | RadA C-terminal ATPase domain from Pyrococcus furiosus | Descriptor: | DNA REPAIR AND RECOMBINATION PROTEIN RADA, PHOSPHATE ION | Authors: | Marsh, M.E, Ehebauer, M.T, Scott, D, Abell, C, Blundell, T.L, Hyvonen, M. | Deposit date: | 2011-11-08 | Release date: | 2012-11-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.498 Å) | Cite: | ATP Half-Sites in Rada and Rad51 Recombinases Bind Nucleotides FEBS Open Bio, 6, 2016
|
|
2PA2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2pa2 by Molmil](/molmil-images/mine/2pa2) | Crystal structure of human Ribosomal protein L10 core domain | Descriptor: | 60S ribosomal protein L10, POTASSIUM ION | Authors: | Nishimura, M, Kaminishi, T, Takemoto, C, Kawazoe, M, Yoshida, T, Tanaka, A, Sugano, S, Shirouzu, M, Ohkubo, T, Yokoyama, S, Kobayashi, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-27 | Release date: | 2008-03-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Human Ribosomal Protein L10 Core Domain Reveals Eukaryote-Specific Motifs in Addition to the Conserved Fold J.Mol.Biol., 377, 2008
|
|
2M5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m5t by Molmil](/molmil-images/mine/2m5t) | Solution structure of the 2A proteinase from a common cold agent, human rhinovirus RV-C02, strain W12 | Descriptor: | ZINC ION, human rhinovirus 2A proteinase | Authors: | Lee, W, Frederick, R, Tonelli, M, Troupis, A.T, Reinin, N, Suchy, F.P, Moyer, K, Watters, K, Aceti, D, Palmenberg, A.C, Markley, J.L. | Deposit date: | 2013-03-07 | Release date: | 2014-03-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution Structure of the 2A Protease from a Common Cold Agent, Human Rhinovirus C2, Strain W12. Plos One, 9, 2014
|
|
2M6V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m6v by Molmil](/molmil-images/mine/2m6v) | |
2M01
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m01 by Molmil](/molmil-images/mine/2m01) | Solution structure of Kunitz-type neurotoxin LmKKT-1a from scorpion venom | Descriptor: | Protease inhibitor LmKTT-1a | Authors: | Luo, F, Jiang, L, Liu, M, Chen, Z, Wu, Y. | Deposit date: | 2012-10-15 | Release date: | 2013-11-13 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Genomic and structural characterization of Kunitz-type peptide LmKTT-1a highlights diversity and evolution of scorpion potassium channel toxins. Plos One, 8, 2013
|
|
2M3M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2m3m by Molmil](/molmil-images/mine/2m3m) | |
4ADL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4adl by Molmil](/molmil-images/mine/4adl) | Crystal structures of Rv1098c in complex with malate | Descriptor: | (2S)-2-hydroxybutanedioic acid, FUMARATE HYDRATASE CLASS II | Authors: | Mechaly, A.E, Haouz, A, Miras, I, Weber, P, Shepard, W, Cole, S, Alzari, P.M, Bellinzoni, M. | Deposit date: | 2011-12-26 | Release date: | 2012-04-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis. FEBS Lett., 586, 2012
|
|
4AEN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4aen by Molmil](/molmil-images/mine/4aen) | HLA-DR1 with covalently linked CLIP106-120 in reversed orientation | Descriptor: | GLYCEROL, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Schlundt, A, Guenther, S, Sticht, J, Wieczorek, M, Roske, Y, Heinemann, U, Freund, C. | Deposit date: | 2012-01-11 | Release date: | 2012-08-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex. J.Mol.Biol., 423, 2012
|
|
2MM0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2mm0 by Molmil](/molmil-images/mine/2mm0) | Solution Structures of active Ptr ToxB and its inactive homolog highlight protein dynamics as a modulator of toxin activity | Descriptor: | Host-selective toxin protein | Authors: | Nyarko, A, Singarapu, K, Figueroa, M, Manning, V, Pandelova, I, Wolpert, T, Ciuffetti, L, Barbar, E. | Deposit date: | 2014-03-06 | Release date: | 2014-08-06 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution NMR Structures of Pyrenophora tritici-repentis ToxB and Its Inactive Homolog Reveal Potential Determinants of Toxin Activity. J.Biol.Chem., 289, 2014
|
|