5B28
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![BU of 5b28 by Molmil](/molmil-images/mine/5b28) | The 0.90A structure of human FABP3 F16V mutant complexed with palmitic acid | 分子名称: | Fatty acid-binding protein, heart, PALMITIC ACID, ... | 著者 | Matsuoka, D, Sugiyama, S, Kakinouchi, K, Niiyama, M, Murata, M, Matsuoka, S. | 登録日 | 2016-01-12 | 公開日 | 2017-01-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | The 0.90A structure of human FABP3 F16V mutant complexed with palmitic acid. To Be Published
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7ZXB
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![BU of 7zxb by Molmil](/molmil-images/mine/7zxb) | Crystal structure of human STING in complex with 3',3'-c-(2'dAMP-2'F,2'dAMP) | 分子名称: | 9-[(1~{R},6~{R},8~{R},10~{S},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-18-fluoranyl-3,12-bis(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]purin-6-amine, Stimulator of interferon protein | 著者 | Klima, M, Smola, M, Boura, E. | 登録日 | 2022-05-20 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of human STING in complex with 3',3'-c-(2'dAMP-2'F,2'dAMP) To Be Published
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4JYC
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![BU of 4jyc by Molmil](/molmil-images/mine/4jyc) | MeaB, A Bacterial Homolog of MMAA, in its Apo form | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Methylmalonyl-CoA mutase accessory protein | 著者 | Koutmos, M, Lofgren, M, Padovani, D, Banerjee, R. | 登録日 | 2013-03-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A switch III motif relays signaling between a B12 enzyme and its G-protein chaperone. Nat.Chem.Biol., 9, 2013
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5M5B
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![BU of 5m5b by Molmil](/molmil-images/mine/5m5b) | Crystal structure of Zika virus NS5 methyltransferase | 分子名称: | CHLORIDE ION, GLYCEROL, NS5 methyltransferase, ... | 著者 | Barral, K, Ortiz Lombardia, M, Coutard, B, Decroly, E, Lichiere, J. | 登録日 | 2016-10-21 | 公開日 | 2016-12-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives. J. Virol., 91, 2017
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7ZVK
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![BU of 7zvk by Molmil](/molmil-images/mine/7zvk) | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-IMP) | 分子名称: | 9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9-fluoranyl-3,12,18-tris(oxidanyl)-3,12-bis(oxidanylidene)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]-3~{H}-purin-6-one, Stimulator of interferon protein | 著者 | Klima, M, Smola, M, Boura, E. | 登録日 | 2022-05-16 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP-IMP) To Be Published
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4JXU
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![BU of 4jxu by Molmil](/molmil-images/mine/4jxu) | Structure of aminotransferase ilvE2 from Sinorhizobium meliloti complexed with PLP | 分子名称: | Putative aminotransferase | 著者 | Cooper, D.R, Cymborowski, M.T, Majorek, K.A, Niedzialkowska, E, Porebski, P.J, Stead, M, Hammonds, J, Seidel, R, Ahmed, M, Bonanno, J.B, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-03-28 | 公開日 | 2013-05-29 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of aminotransferase ilvE2 from Sinorhizobium meliloti complexed with PLP To be Published
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4JYB
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![BU of 4jyb by Molmil](/molmil-images/mine/4jyb) | MeaB, A Bacterial Homolog of MMAA, Bound to GMPPNP | 分子名称: | Methylmalonyl-CoA mutase accessory protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Koutmos, M, Lofgren, M, Padovani, D, Banerjee, R. | 登録日 | 2013-03-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A switch III motif relays signaling between a B12 enzyme and its G-protein chaperone. Nat.Chem.Biol., 9, 2013
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6G8H
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![BU of 6g8h by Molmil](/molmil-images/mine/6g8h) | Flavonoid-responsive Regulator FrrA in complex with (R,S)-Naringenin | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, NARINGENIN, R-naringenin, ... | 著者 | Werner, N, Hoppen, J, Palm, G, Werten, S, Goettfert, M, Hinrichs, W. | 登録日 | 2018-04-08 | 公開日 | 2019-04-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The induction mechanism of the flavonoid-responsive regulator FrrA. Febs J., 2021
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5AQT
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![BU of 5aqt by Molmil](/molmil-images/mine/5aqt) | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | 分子名称: | (1S,2R,3R,5R)-3-(hydroxymethyl)-5-(quinazolin-4-ylamino)cyclopentane-1,2-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | 著者 | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | 登録日 | 2015-09-22 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
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6TS5
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![BU of 6ts5 by Molmil](/molmil-images/mine/6ts5) | Coagulation factor XI protease domain in complex with active site inhibitor | 分子名称: | 2-[2-[3-[(3~{S})-3-azanyl-2,3-dihydro-1-benzofuran-5-yl]-5-propan-2-yl-phenyl]ethoxy]-3-methoxy-benzoic acid, Coagulation factor XI, DIMETHYL SULFOXIDE, ... | 著者 | Renatus, M, Schiering, N. | 登録日 | 2019-12-20 | 公開日 | 2020-07-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach. J.Med.Chem., 63, 2020
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8A2X
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![BU of 8a2x by Molmil](/molmil-images/mine/8a2x) | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S)) | 分子名称: | 9-[(1~{R},3~{R},6~{R},8~{R},9~{R},10~{R},12~{R},15~{R},17~{R},18~{S})-8-(6-aminopurin-9-yl)-9,18-bis(fluoranyl)-3,12-bis(oxidanylidene)-3,12-bis(sulfanyl)-2,4,7,11,13-pentaoxa-3$l^{5},12$l^{5}-diphosphatricyclo[13.3.0.0^{6,10}]octadecan-17-yl]purin-6-amine, Stimulator of interferon protein | 著者 | Klima, M, Smola, M, Boura, E. | 登録日 | 2022-06-06 | 公開日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of human STING in complex with 3',3'-c-(2'F,2'dAMP(S)-2'F,2'dAMP(S)) To Be Published
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5X2B
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1LA1
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![BU of 1la1 by Molmil](/molmil-images/mine/1la1) | Gro-EL Fragment (Apical Domain) Comprising Residues 188-379 | 分子名称: | GroEL | 著者 | Ashcroft, A.E, Brinker, A, Coyle, J.E, Weber, F, Kaiser, M, Moroder, L, Parsons, M.R, Jager, J, Hartl, U.F, Hayer-Hartl, M, Radford, S.E. | 登録日 | 2002-03-27 | 公開日 | 2002-04-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Structural plasticity and noncovalent substrate binding in the GroEL apical domain. A study using electrospay ionization mass spectrometry and fluorescence binding studies. J.Biol.Chem., 277, 2002
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8GB1
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![BU of 8gb1 by Molmil](/molmil-images/mine/8gb1) | Crystal structure of SAMHD1 dimer bound to deoxyguanosine linked inhibitor | 分子名称: | 5'-O-[(R)-(3-{[(1M)-3'-bromo[1,1'-biphenyl]-3-carbonyl]amino}propoxy)(hydroxy)phosphoryl]-2'-deoxyguanosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION | 著者 | Egleston, M, Dong, L, Howlader, A.H, Bhat, S, Orris, B, Bianchet, M.A, Greenberg, M.M, Stivers, J.T. | 登録日 | 2023-02-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Deoxyguanosine-Linked Bifunctional Inhibitor of SAMHD1 dNTPase Activity and Nucleic Acid Binding. Acs Chem.Biol., 18, 2023
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1S6M
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![BU of 1s6m by Molmil](/molmil-images/mine/1s6m) | Conjugative Relaxase Trwc In Complex With Orit DNA. Metal-Bound Structure | 分子名称: | DNA (25-MER), NICKEL (II) ION, TrwC | 著者 | Guasch, A, Lucas, M, Moncalian, G, Cabezas, M, Perez-Luque, R, Gomis-Ruth, F.X, de la Cruz, F, Coll, M. | 登録日 | 2004-01-26 | 公開日 | 2005-06-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Unveiling the molecular mechanism of a conjugative relaxase: The structure of TrwC complexed with a 27-mer DNA comprising the recognition hairpin and the cleavage site. J.Mol.Biol., 358, 2006
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6JND
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![BU of 6jnd by Molmil](/molmil-images/mine/6jnd) | Cryo-EM structure of glutamate dehydrogenase from Thermococcus profundus | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutamate dehydrogenase | 著者 | Oide, M, Kato, T, Oroguchi, T, Nakasako, M. | 登録日 | 2019-03-14 | 公開日 | 2020-02-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Energy landscape of domain motion in glutamate dehydrogenase deduced from cryo-electron microscopy. Febs J., 287, 2020
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1LB9
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![BU of 1lb9 by Molmil](/molmil-images/mine/1lb9) | Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with antagonist DNQX at 2.3 A resolution | 分子名称: | 6,7-DINITROQUINOXALINE-2,3-DIONE, Glutamate receptor 2, SULFATE ION | 著者 | Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E. | 登録日 | 2002-04-02 | 公開日 | 2002-06-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanism of glutamate receptor desensitization. Nature, 417, 2002
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6T3R
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1C9T
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![BU of 1c9t by Molmil](/molmil-images/mine/1c9t) | COMPLEX OF BDELLASTASIN WITH BOVINE TRYPSIN | 分子名称: | BDELLASTASIN, TRYPSIN | 著者 | Rester, U, Bode, W, Moser, M, Parry, M.A, Huber, R, Auerswald, E. | 登録日 | 1999-08-03 | 公開日 | 2000-08-03 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the complex of the antistasin-type inhibitor bdellastasin with trypsin and modelling of the bdellastasin-microplasmin system. J.Mol.Biol., 293, 1999
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8GSY
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4K1T
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![BU of 4k1t by Molmil](/molmil-images/mine/4k1t) | Gly-Ser-SplB protease from Staphylococcus aureus at 1.60 A resolution | 分子名称: | CHLORIDE ION, SULFATE ION, Serine protease SplB, ... | 著者 | Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G. | 登録日 | 2013-04-05 | 公開日 | 2014-04-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation. J.Biol.Chem., 289, 2014
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1LRU
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![BU of 1lru by Molmil](/molmil-images/mine/1lru) | Crystal Structure of E.coli Peptide Deformylase Complexed with Antibiotic Actinonin | 分子名称: | ACTINONIN, PEPTIDE DEFORMYLASE, SULFATE ION, ... | 著者 | Guilloteau, J.-P, Mathieu, M, Giglione, C, Blanc, V, Dupuy, A, Chevrier, M, Gil, P, Famechon, A, Meinnel, T, Mikol, V. | 登録日 | 2002-05-16 | 公開日 | 2002-07-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structures of four peptide deformylases bound to the antibiotic actinonin reveal two distinct types: a platform for the structure-based design of antibacterial agents. J.Mol.Biol., 320, 2002
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6GGK
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![BU of 6ggk by Molmil](/molmil-images/mine/6ggk) | Crystal structure of CotB2 C-terminal truncation | 分子名称: | CHLORIDE ION, Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION | 著者 | Driller, R, Janke, S, Fuchs, M, Warner, E, Mhashal, A.R, Major, D.T, Christmann, M, Brueck, T, Loll, B. | 登録日 | 2018-05-03 | 公開日 | 2018-10-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis. Nat Commun, 9, 2018
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8G55
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1KYX
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![BU of 1kyx by Molmil](/molmil-images/mine/1kyx) | Lumazine Synthase from S.pombe bound to carboxyethyllumazine | 分子名称: | 3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID, 6,7-Dimethyl-8-ribityllumazine Synthase, PHOSPHATE ION | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2002-02-06 | 公開日 | 2002-07-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase. J.Mol.Biol., 318, 2002
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