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PDB: 51938 件

2OM7
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Structural Basis for Interaction of the Ribosome with the Switch Regions of GTP-bound Elongation Factors
分子名称: 16S ribosomal RNA (H5), 30S ribosomal protein S12, 30S ribosomal protein S2, ...
著者Connell, S.R, Wilson, D.N, Rost, M, Schueler, M, Giesebrecht, J, Dabrowski, M, Mielke, T, Fucini, P, Spahn, C.M.T.
登録日2007-01-21
公開日2008-01-15
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Mol.Cell, 25, 2007
2P3U
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BU of 2p3u by Molmil
Crystal structure of human factor XA complexed with 3-chloro-N-(4-chloro-2-{[(5-chloropyridin-2-yl)amino]carbonyl}-6-methoxyphenyl)-4-[(1-methyl-1H-imidazol-2-yl)methyl]thiophene-2-carboxamide {Pfizer 320663}
分子名称: 3-CHLORO-N-(4-CHLORO-2-{[(5-CHLOROPYRIDIN-2-YL)AMINO]CARBONYL}-6-METHOXYPHENYL)-4-[(1-METHYL-1H-IMIDAZOL-2-YL)METHYL]THIOPHENE-2-CARBOXAMIDE, CALCIUM ION, Coagulation factor X
著者Adler, M, Whitlow, M.
登録日2007-03-09
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献

2PE2
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CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) 3-{5-[2-Oxo-5-ureido-1,2-dihydro-indol-(3Z)-ylidenemethyl]-1H-pyrrol-3-yl}-N-(2-piperidin-1-yl-ethyl)-benzamide COMPLEX
分子名称: 3-[5-({5-[(AMINOCARBONYL)AMINO]-2-OXO-2H-INDOL-3-YL}METHYL)-1H-PYRROL-3-YL]-N-(2-PIPERIDIN-1-YLETHYL)BENZAMIDE, 3-phosphoinositide-dependent protein kinase 1, GLYCEROL, ...
著者Whitlow, M, Adler, M.
登録日2007-04-01
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 2: Optimization of BX-517.
Bioorg.Med.Chem.Lett., 17, 2007
2PD0
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BU of 2pd0 by Molmil
Protein cgd2_2020 from Cryptosporidium parvum
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hypothetical protein
著者Cymborowski, M, Chruszcz, M, Hills, T, Lew, J, Melone, M, Zhao, Y, Artz, J, Wernimont, A, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Arrowsmith, C, Hui, R, Minor, W, Structural Genomics Consortium (SGC)
登録日2007-03-30
公開日2007-04-17
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Protein cgd2_2020 from Cryptosporidium parvum
To be Published
6OEB
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BU of 6oeb by Molmil
Crystal structure of HMCES SRAP domain in complex with 3' overhang DNA
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ...
著者Halabelian, L, Ravichandran, M, Li, Y, Zeng, H, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2019-03-27
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.
Nat.Struct.Mol.Biol., 26, 2019
2QC3
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BU of 2qc3 by Molmil
Crystal structure of MCAT from Mycobacterium tuberculosis
分子名称: ACETIC ACID, Malonyl CoA-acyl carrier protein transacylase
著者Li, Z, Huang, Y, Ge, J, Bartlam, M, Wang, H, Rao, Z.
登録日2007-06-19
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models.
J.Mol.Biol., 371, 2007
5MXN
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BU of 5mxn by Molmil
Atomic model of the VipA/VipB/Hcp, the type six secretion system non-contractile sheath-tube of Vibrio cholerae from cryo-EM
分子名称: Haemolysin co-regulated protein, Type VI secretion protein
著者Wang, J, Brackmann, M, Castano-Diez, D, Kudryashev, M, Goldie, K, Maier, T, Stahlberg, H, Basler, M.
登録日2017-01-23
公開日2017-08-02
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the extended type VI secretion system sheath-tube complex.
Nat Microbiol, 2, 2017
1HPK
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BU of 1hpk by Molmil
SOLUTION NMR STRUCTURE OF THE HUMAN PLASMINOGEN KRINGLE 1 DOMAIN COMPLEXED WITH 6-AMINOHEXANOIC ACID AT PH 5.3, 310K, DERIVED FROM RANDOMLY GENERATED STRUCTURES USING SIMULATED ANNEALING, MINIMIZED AVERAGE STRUCTURE
分子名称: 6-AMINOHEXANOIC ACID, PLASMINOGEN
著者Rejante, M, Llinas, M.
登録日1996-08-14
公開日1997-03-12
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Solution structure of the epsilon-aminohexanoic acid complex of human plasminogen kringle 1.
Eur.J.Biochem., 221, 1994
7R2V
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BU of 7r2v by Molmil
Structure of nsp14 from SARS-CoV-2 in complex with SAH
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Proofreading exoribonuclease nsp14, ...
著者Czarna, A, Plewka, J, Kresik, L, Matsuda, A, Abdulkarim, K, Robinson, C, OByrne, S, Cunningham, F, Georgiou, I, Pachota, M, Popowicz, G.M, Wyatt, P.G, Dubin, G, Pyrc, K.
登録日2022-02-06
公開日2022-03-09
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity.
Structure, 30, 2022
2YT8
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BU of 2yt8 by Molmil
Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma)
分子名称: Amyloid beta A4 precursor protein-binding family A member 3
著者Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Seiki, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-04-05
公開日2008-04-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3 (Neuron- specific X11L2 protein) (Neuronal Munc18-1-interacting protein 3) (Mint-3) (Adapter protein X11gamma)
To be Published
6O8Q
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BU of 6o8q by Molmil
HUaa 19bp SYM DNA pH 4.5
分子名称: DNA (57-MER), DNA-binding protein HU-alpha
著者Remesh, S.G, Hammel, M.
登録日2019-03-11
公開日2020-03-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.216 Å)
主引用文献Nucleoid remodeling during environmental adaptation is regulated by HU-dependent DNA bundling.
Nat Commun, 11, 2020
7XRF
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BU of 7xrf by Molmil
Crystal structaure of DgpB/C complex
分子名称: AP_endonuc_2 domain-containing protein, DgpB, MANGANESE (II) ION
著者Ma, M, He, P.
登録日2022-05-10
公開日2023-02-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.137 Å)
主引用文献Structural mechanism of a dual-functional enzyme DgpA/B/C as both a C -glycoside cleaving enzyme and an O - to C -glycoside isomerase.
Acta Pharm Sin B, 13, 2023
8AED
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BU of 8aed by Molmil
Broadly neutralizing DARPin bnD.9 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BG505)
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.9, ...
著者Mittl, P, Gloegl, M.
登録日2022-07-13
公開日2023-08-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.17 Å)
主引用文献Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Nat.Struct.Mol.Biol., 30, 2023
4MMV
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BU of 4mmv by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1-TriC at pH 9.5
分子名称: Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2
著者Stewart-Jones, G.B.E, McLellan, J.S, Joyce, M.G, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
登録日2013-09-09
公開日2013-11-20
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4I47
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BU of 4i47 by Molmil
Crystal structure of the Ribosome inactivating protein complexed with methylated guanine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, rRNA N-glycosidase
著者Yamini, S, Kushwaha, G.S, Bhushan, A, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2012-11-27
公開日2012-12-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina.
Proteins, 81, 2013
6OQR
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BU of 6oqr by Molmil
E. coli ATP Synthase ADP State 1a
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Stewart, A.G, Walshe, J.L, Sobti, M.
登録日2019-04-29
公開日2020-06-03
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch.
Nat Commun, 11, 2020
6QXZ
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BU of 6qxz by Molmil
Solution structure of the ASHH2 CW domain with the N-terminal histone H3 tail mimicking peptide monomethylated on lysine 4
分子名称: ALA-ARG-THR-MLZ-GLN-THR-ALA-ARG-TYR, Histone-lysine N-methyltransferase ASHH2, ZINC ION
著者Dobrovolska, O, Madeleine, N, Teigen, K, Halskau, O, Bril'kov, M.
登録日2019-03-08
公開日2019-12-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Arabidopsis (ASHH2) CW domain binds monomethylated K4 of the histone H3 tail through conformational selection.
Febs J., 287, 2020
7RBY
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BU of 7rby by Molmil
Crystal structure of Nanobody nb112 and SARS-CoV-2 RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ilama-isolated nanobody NIH-CoV nb-112 specific to SARS-CoV-2 RBD, MAGNESIUM ION, ...
著者Chen, Y, Tolbert, W, Pazgier, M.
登録日2021-07-06
公開日2022-03-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological, and pathological disease in a Syrian hamster model of COVID-19.
Mabs, 14
6OES
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BU of 6oes by Molmil
Cryo-EM structure of mouse RAG1/2 STC complex (without NBD domain)
分子名称: CALCIUM ION, DNA (34-MER), DNA (35-MER), ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献How mouse RAG recombinase avoids DNA transposition.
Nat.Struct.Mol.Biol., 27, 2020
6OF0
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BU of 6of0 by Molmil
Structural basis for multidrug recognition and antimicrobial resistance by MTRR, an efflux pump regulator from Neisseria Gonorrhoeae
分子名称: HTH-type transcriptional regulator MtrR, PHOSPHATE ION
著者Beggs, G.A, Kumaraswami, M, Shafer, W, Brennan, R.G.
登録日2019-03-28
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae .
J.Bacteriol., 201, 2019
7R03
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BU of 7r03 by Molmil
Neurofibromin occluded conformation
分子名称: Isoform I of Neurofibromin
著者Chaker-Margot, M, Scheffzek, K, Maier, T.
登録日2022-02-01
公開日2022-03-30
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of activation of the tumor suppressor protein neurofibromin.
Mol.Cell, 82, 2022
5FVB
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CRYSTAL STRUCTURE OF PHORMIDIUM C-PHYCOERYTHRIN AT PH 5.0
分子名称: C-PHYCOERYTHRIN ALPHA SUBUNIT, C-PHYCOERYTHRIN BETA SUBUNIT, GLYCEROL, ...
著者Kumar, V, Sonani, R.R, Sharma, M, Gupta, G.D, Madamwar, D.
登録日2016-02-05
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure Analysis of C-Phycoerythrin from Marine Cyanobacterium Phormidium Sp. A09Dm.
Photosynth.Res., 129, 2016
5MVD
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Crystal structure of potent human Dihydroorotate Dehydrogenase inhibitors based on hydroxylated azole scaffolds
分子名称: 1,5-dimethyl-3-oxidanyl-~{N}-[2,3,5,6-tetrakis(fluoranyl)-4-phenyl-phenyl]pyrazole-4-carboxamide, ACETATE ION, CHLORIDE ION, ...
著者Goyal, P, Andersson, M, Moritzer, A.C, Sainas, S, Pippione, A.C, Boschi, D, Al-Kadaraghi, S, Lolli, M, Friemann, R.
登録日2017-01-16
公開日2017-03-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds.
Eur J Med Chem, 129, 2017
7R04
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BU of 7r04 by Molmil
Neurofibromin in open conformation
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform I of Neurofibromin
著者Chaker-Margot, M, Scheffzek, K, Maier, T.
登録日2022-02-01
公開日2022-03-30
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of activation of the tumor suppressor protein neurofibromin.
Mol.Cell, 82, 2022
4MMU
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BU of 4mmu by Molmil
Crystal Structure of Prefusion-stabilized RSV F Variant DS-Cav1 at pH 5.5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F1 fused with Fibritin trimerization domain, Fusion glycoprotein F2, ...
著者Joyce, M.G, Mclellan, J.S, Stewart-Jones, G.B.E, Sastry, M, Yang, Y, Graham, B.S, Kwong, P.D.
登録日2013-09-09
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013

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