6NOV
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![BU of 6nov by Molmil](/molmil-images/mine/6nov) | A Fab derived from ixekizumab | 分子名称: | DODECAETHYLENE GLYCOL, Fab Heavy Chain, Fab Light Chain | 著者 | Durbin, J.D, Clawson, D.K, Lu, F, Tian, Y, Lu, J, Schmitt, M, Atwell, S. | 登録日 | 2019-01-16 | 公開日 | 2019-06-19 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Development of tibulizumab, a tetravalent bispecific antibody targeting BAFF and IL-17A for the treatment of autoimmune disease. Mabs, 11, 2019
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6SFG
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![BU of 6sfg by Molmil](/molmil-images/mine/6sfg) | CRYSTAL STRUCTURE OF DHQ1 FROM SALMONELLA TYPHI COVALENTLY MODIFIED BY COMPOUND 9 | 分子名称: | (1~{R},3~{S},4~{R},5~{R})-3-methyl-4,5-bis(hydroxyl)cyclohexane-1-carboxylic acid, (1~{S},3~{R},4~{S},5~{R})-3-methyl-3,4,5-tris(hydroxyl)cyclohexane-1-carboxylic Acid, 3-dehydroquinate dehydratase | 著者 | Sanz-Gaitero, M, Lence, E, Maneiro, M, Thompson, R, Hawkins, A.R, Gonzalez-Bello, C, van Raaij, M.J. | 登録日 | 2019-08-01 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Self-Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product. Chemistry, 26, 2020
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5UI6
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![BU of 5ui6 by Molmil](/molmil-images/mine/5ui6) | Solution NMR Structure of Lasso Peptide Acinetodin | 分子名称: | Acinetodin | 著者 | Bushin, L.B, Metelev, M, Severinov, K, Seyedsayamdost, M.R. | 登録日 | 2017-01-12 | 公開日 | 2017-02-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae. ACS Chem. Biol., 12, 2017
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1Y8V
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![BU of 1y8v by Molmil](/molmil-images/mine/1y8v) | Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-propyl Thymidine (T*) | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(P2T)P*AP*CP*GP*C)-3' | 著者 | Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. | 登録日 | 2004-12-13 | 公開日 | 2005-06-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications. Biochemistry, 44, 2005
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3O6R
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![BU of 3o6r by Molmil](/molmil-images/mine/3o6r) | Crystal Structure of 4-Chlorocatechol Dioxygenase from Rhodococcus opacus 1CP in complex with pyrogallol | 分子名称: | (2R)-3-(PHOSPHONOOXY)-2-(TETRADECANOYLOXY)PROPYL PALMITATE, BENZENE-1,2,3-TRIOL, Chlorocatechol 1,2-dioxygenase, ... | 著者 | Ferraroni, M, Briganti, F, Kolomitseva, M, Golovleva, L. | 登録日 | 2010-07-29 | 公開日 | 2011-08-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | X-ray structures of 4-chlorocatechol 1,2-dioxygenase adducts with substituted catechols: new perspectives in the molecular basis of intradiol ring cleaving dioxygenases specificity. J. Struct. Biol., 181, 2013
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3OFJ
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![BU of 3ofj by Molmil](/molmil-images/mine/3ofj) | Crystal structure of N-methyltransferase NodS from Bradyrhizobium japonicum WM9 | 分子名称: | Nodulation protein S | 著者 | Cakici, O, Sikorski, M, Stepkowski, T, Bujacz, G, Jaskolski, M. | 登録日 | 2010-08-15 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Crystal Structures of NodS N-Methyltransferase from Bradyrhizobium japonicum in Ligand-Free Form and as SAH Complex. J.Mol.Biol., 404, 2010
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8AF4
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![BU of 8af4 by Molmil](/molmil-images/mine/8af4) | Room temperature SSX structure of GH11 xylanase from Nectria haematococca (40000 frames) | 分子名称: | Endo-1,4-beta-xylanase | 著者 | Oberthuer, D, Andaleeb, H, Betzel, C, Perbandt, M, Yefanov, O, Zielinski, K. | 登録日 | 2022-07-15 | 公開日 | 2022-11-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive. Iucrj, 9, 2022
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8AF8
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![BU of 8af8 by Molmil](/molmil-images/mine/8af8) | Room temperature SSX crystal structure of CTX-M-14 (5K dataset) | 分子名称: | Beta-lactamase, SULFATE ION | 著者 | Oberthuer, D, Perbandt, M, Prester, A, Rohde, H, Betzel, C, Yefanov, O. | 登録日 | 2022-07-15 | 公開日 | 2022-11-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive. Iucrj, 9, 2022
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1LQM
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![BU of 1lqm by Molmil](/molmil-images/mine/1lqm) | ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE COMPLEX WITH URACIL-DNA GLYCOSYLASE INHIBITOR PROTEIN | 分子名称: | URACIL-DNA GLYCOSYLASE, URACIL-DNA GLYCOSYLASE INHIBITOR | 著者 | Saikrishnan, K, Sagar, M.B, Ravishankar, R, Roy, S, Purnapatre, K, Varshney, U, Vijayan, M. | 登録日 | 2002-05-10 | 公開日 | 2002-11-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG. Acta Crystallogr.,Sect.D, 58, 2002
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8AF5
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![BU of 8af5 by Molmil](/molmil-images/mine/8af5) | Room temperature SSX structure of GH11 xylanase from Nectria haematococca (10000 frames) | 分子名称: | Endo-1,4-beta-xylanase | 著者 | Oberthuer, D, Andaleeb, H, Betzel, C, Perbandt, M, Yefanov, O, Zielinski, K. | 登録日 | 2022-07-15 | 公開日 | 2022-11-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive. Iucrj, 9, 2022
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1UHA
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![BU of 1uha by Molmil](/molmil-images/mine/1uha) | Crystal Structure of Pokeweed Lectin-D2 | 分子名称: | CALCIUM ION, lectin-D2 | 著者 | Fujii, T, Hayashida, M, Hamasu, M, Ishiguro, M, Hata, Y. | 登録日 | 2003-06-27 | 公開日 | 2004-04-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of two lectins from the roots of pokeweed (Phytolacca americana). Acta Crystallogr.,Sect.D, 60, 2004
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1LMT
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![BU of 1lmt by Molmil](/molmil-images/mine/1lmt) | |
1BBZ
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![BU of 1bbz by Molmil](/molmil-images/mine/1bbz) | |
6NFW
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![BU of 6nfw by Molmil](/molmil-images/mine/6nfw) | |
2CD1
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5E37
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![BU of 5e37 by Molmil](/molmil-images/mine/5e37) | Redox protein from Chlamydomonas reinhardtii | 分子名称: | CALCIUM ION, EF-Hand domain-containing thioredoxin | 著者 | Charoenwattansatien, R, Hochmal, A.K, Zinzius, K, Muto, R, Tanaka, H, Hippler, M, Kurisu, G. | 登録日 | 2015-10-02 | 公開日 | 2016-06-22 | 最終更新日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Calredoxin represents a novel type of calcium-dependent sensor-responder connected to redox regulation in the chloroplast Nat Commun, 7, 2016
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1ULN
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![BU of 1uln by Molmil](/molmil-images/mine/1uln) | Crystal Structure of Pokeweed Lectin-D1 | 分子名称: | lectin-D | 著者 | Fujii, T, Hayashida, M, Hamasu, M, Ishiguro, M, Hata, Y. | 登録日 | 2003-09-16 | 公開日 | 2004-04-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structures of two lectins from the roots of pokeweed (Phytolacca americana). Acta Crystallogr.,Sect.D, 60, 2004
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5EC9
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![BU of 5ec9 by Molmil](/molmil-images/mine/5ec9) | Retinoic acid receptor alpha in complex with chiral dihydrobenzofuran benzoic acid 9a and a fragment of the coactivator TIF2 | 分子名称: | 4-[(11S,15R)-4,4,7,7-Tetramethyl-16-oxatetracyclo[8.6.0.03,8.011,15]hexadeca-1(10),2,8-trien-11-yl]benzoic acid, LYS-HIS-LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN-ASP, Retinoic acid receptor RXR-alpha | 著者 | Leysen, S, Ottmann, C, Schafer, A, Scheepstra, M, Brunsveld, L, Sunden, R, Ma, J.N, Burnstein, E.S, Olsson, R. | 登録日 | 2015-10-20 | 公開日 | 2016-03-09 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation. J.Med.Chem., 59, 2016
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1BDA
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5ED3
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![BU of 5ed3 by Molmil](/molmil-images/mine/5ed3) | crystal structure of human Hint1 complexing with AP5A | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 | 著者 | Wang, J, Fang, P, Guo, M. | 登録日 | 2015-10-20 | 公開日 | 2017-01-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.309 Å) | 主引用文献 | Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10, 2019
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1ULM
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![BU of 1ulm by Molmil](/molmil-images/mine/1ulm) | Crystal Structure of Pokeweed Lectin-D2 complexed with tri-N-acetylchitotriose | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, lectin-D2 | 著者 | Hayashida, M, Fujii, T, Ishiguro, M, Hata, Y. | 登録日 | 2003-09-12 | 公開日 | 2003-12-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Similarity between protein-protein and protein-carbohydrate interactions, revealed by two crystal structures of lectins from the roots of pokeweed. J.Mol.Biol., 334, 2003
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7OAM
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![BU of 7oam by Molmil](/molmil-images/mine/7oam) | Kinase domain of MERTK in complex with compound 8 | 分子名称: | 1,2-ETHANEDIOL, 2-[[2,5-bis(fluoranyl)phenyl]methylamino]-4-(cyclopentylamino)-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide, Tyrosine-protein kinase Mer | 著者 | Schroeder, M, Russ, N, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-04-19 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase. J.Med.Chem., 64, 2021
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2PD0
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![BU of 2pd0 by Molmil](/molmil-images/mine/2pd0) | Protein cgd2_2020 from Cryptosporidium parvum | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Hypothetical protein | 著者 | Cymborowski, M, Chruszcz, M, Hills, T, Lew, J, Melone, M, Zhao, Y, Artz, J, Wernimont, A, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Arrowsmith, C, Hui, R, Minor, W, Structural Genomics Consortium (SGC) | 登録日 | 2007-03-30 | 公開日 | 2007-04-17 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Protein cgd2_2020 from Cryptosporidium parvum To be Published
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6HVE
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![BU of 6hve by Molmil](/molmil-images/mine/6hve) | Kinase domain of cSrc in complex with compound 9 | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, ~{N}-[3-(4-methoxy-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]prop-2-enamide | 著者 | Keul, M, Mueller, M.P, Rauh, D. | 登録日 | 2018-10-10 | 公開日 | 2019-10-23 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S. Chem Sci, 10, 2019
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6W8M
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![BU of 6w8m by Molmil](/molmil-images/mine/6w8m) | Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments | 分子名称: | 2-oxo-1,2-dihydroquinazoline-4-carboxylic acid, Nonstructural polyprotein | 著者 | Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. | 登録日 | 2020-03-20 | 公開日 | 2021-01-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
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