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6NFW

Potyvirus viral protein genome linked (VPg) emulates the m7G cap to recruit the eukaryotic translation initiation factor eIF4E

Summary for 6NFW
Entry DOI10.2210/pdb6nfw/pdb
NMR InformationBMRB: 27506
DescriptorVPg (1 entity in total)
Functional Keywordspotyvirus, viral protein
Biological sourcePotato virus Y
Total number of polymer chains1
Total formula weight21657.43
Authors
Borden, K.,Volpon, L.,Osborne, M. (deposition date: 2018-12-21, release date: 2019-11-06, Last modification date: 2023-06-14)
Primary citationCoutinho de Oliveira, L.,Volpon, L.,Rahardjo, A.K.,Osborne, M.J.,Culjkovic-Kraljacic, B.,Trahan, C.,Oeffinger, M.,Kwok, B.H.,Borden, K.L.B.
Structural studies of the eIF4E-VPg complex reveal a direct competition for capped RNA: Implications for translation.
Proc.Natl.Acad.Sci.USA, 116:24056-24065, 2019
Cited by
PubMed: 31712417
DOI: 10.1073/pnas.1904752116
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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