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PDB: 51689 件

7PRM
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CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 13
分子名称: (4~{R})-1-[4-(4-fluorophenyl)phenyl]-4-[4-(furan-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one, 1,2-ETHANEDIOL, Monoglyceride lipase
著者Grether, U, Gobbi, L, Kuhn, B, Collin, L, Leibrock, L, Heer, D, Wittwer, M, Benz, J.
登録日2021-09-22
公開日2022-02-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Development of High Brain-Penetrant and Reversible Monoacylglycerol Lipase PET Tracers for Neuroimaging.
J.Med.Chem., 65, 2022
7Z4J
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SpCas9 bound to 18-nucleotide complementary DNA substrate in the catalytic state
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ...
著者Pacesa, M, Jinek, M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
6OL6
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Structure of iglb12 scFv in complex with anti-idiotype ib2 Fab
分子名称: CHLORIDE ION, ib2 Heavy Chain, ib2 Light Chain, ...
著者Weidle, C, Pancera, M, Gewe, M.
登録日2019-04-15
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
7Z4L
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SpCas9 bound to 18-nucleotide complementary DNA substrate in the checkpoint state
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, Non-target strand of 18-nucleotide complementary DNA substrate, ...
著者Pacesa, M, Jinek, M.
登録日2022-03-04
公開日2022-08-31
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
1IOK
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CRYSTAL STRUCTURE OF CHAPERONIN-60 FROM PARACOCCUS DENITRIFICANS
分子名称: CHAPERONIN 60
著者Fukami, T.A, Yohda, M, Taguchi, H, Yoshida, M, Miki, K.
登録日2001-03-16
公開日2001-10-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of chaperonin-60 from Paracoccus denitrificans.
J.Mol.Biol., 312, 2001
1IRR
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Solution structure of paralytic peptide of the silkworm, Bombyx mori
分子名称: paralytic peptide
著者Miura, K, Kamimura, M, Aizawa, T, Kiuchi, M, Hayakawa, Y, Mizuguchi, M, Kawano, K.
登録日2001-10-23
公開日2003-02-11
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of paralytic peptide of silkworm, Bombyx mori
peptides, 23, 2002
5EOY
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Pseudomonas aeruginosa SeMet-PilM bound to ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Type 4 fimbrial biogenesis protein PilM
著者McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L.L, Howell, P.L.
登録日2015-11-10
公開日2016-04-27
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.
J.Biol.Chem., 291, 2016
7Z4D
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Crystal structure of SpCas9 bound to a 10 nucleotide complementary DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand of 10 nucleotide complementary DNA substrate, POTASSIUM ION, ...
著者Pacesa, M, Jinek, M.
登録日2022-03-03
公開日2022-08-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献R-loop formation and conformational activation mechanisms of Cas9.
Nature, 609, 2022
7PE1
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Cryo-EM structure of BMV-derived VLP expressed in E. coli and assembled in the presence of tRNA (tVLP)
分子名称: Coat protein
著者Ruszkowski, M, Strugala, A, Indyka, P, Urbanowicz, A.
登録日2021-08-09
公開日2022-03-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Cryo-EM reconstructions of BMV-derived virus-like particles reveal assembly defects in the icosahedral lattice structure.
Nanoscale, 14, 2022
7PE2
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Cryo-EM structure of BMV-derived VLP expressed in E. coli (eVLP)
分子名称: Coat protein
著者Ruszkowski, M, Strugala, A, Indyka, P, Urbanowicz, A.
登録日2021-08-09
公開日2022-03-02
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM reconstructions of BMV-derived virus-like particles reveal assembly defects in the icosahedral lattice structure.
Nanoscale, 14, 2022
5EQ6
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Pseudomonas aeruginosa PilM bound to AMP-PNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Type 4 fimbrial biogenesis protein PilM
著者McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L.L, Howell, P.L.
登録日2015-11-12
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM.
J.Biol.Chem., 291, 2016
7Z49
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The capsid of bacteriophage SU10.
分子名称: Major head protein
著者Siborova, M, Fuzik, T, Prochazkova, M, Novacek, J, Plevka, P.
登録日2022-03-03
公開日2022-10-05
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Tail proteins of phage SU10 reorganize into the nozzle for genome delivery.
Nat Commun, 13, 2022
1IX5
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Solution structure of the Methanococcus thermolithotrophicus FKBP
分子名称: FKBP
著者Suzuki, R, Nagata, K, Kawakami, M, Nemoto, N, Furutani, M, Adachi, K, Maruyama, T, Tanokura, M.
登録日2002-06-12
公開日2003-06-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Three-dimensional Solution Structure of an Archaeal FKBP with a Dual Function of Peptidyl Prolyl cis-trans Isomerase and Chaperone-like Activities
J.MOL.BIOL., 328, 2003
1A2B
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HUMAN RHOA COMPLEXED WITH GTP ANALOGUE
分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA
著者Ihara, K, Muraguchi, S, Kato, M, Shimizu, T, Shirakawa, M, Kuroda, S, Kaibuchi, K, Hakoshima, T.
登録日1997-12-26
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.
J.Biol.Chem., 273, 1998
4ZQP
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Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis in the complex with IMP and the inhibitor MAD1
分子名称: 5'-O-({1-[(2E)-4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-2-methylbut-2-en-1-yl]-1H-1,2,3-triazol-4-yl}methyl)adenosine, GLYCEROL, INOSINIC ACID, ...
著者Kim, Y, Makowska-Grzyska, M, Gu, M, Kavitha, M, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-05-10
公開日2015-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.
Plos One, 10, 2015
7PP0
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Crystal structure of the VIM-2 acquired metallo-beta-Lactamase in complex with compound 28 (JMV-7038)
分子名称: 2-[2-[3-[3-(2-morpholin-4-ylethoxy)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]ethyl]benzoic acid, ACETATE ION, Metallo-beta-lactamase VIM-2-like protein, ...
著者Tassone, G, Benvenuti, M, Verdirosa, F, Corsica, G, Chelini, G, De Luca, F, Docquier, J.D, Pozzi, C, Mangani, S.
登録日2021-09-10
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-beta-Lactamase Inhibitors.
Chemmedchem, 17, 2022
6S82
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Structure Of D80A-Fructofuranosidase From Xanthophyllomyces Dendrorhous Complexed With Tris-buffer molecule And hydroquinone
分子名称: 1,2-ETHANEDIOL, 1,4-benzoquinone, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Ramirez-Escudero, M, Sanz-Aparicio, J.
登録日2019-07-08
公開日2020-04-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Deciphering the molecular specificity of phenolic compounds as inhibitors or glycosyl acceptors of beta-fructofuranosidase from Xanthophyllomyces dendrorhous.
Sci Rep, 9, 2019
1IX4
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Crystal Structure of Rat Heme Oxygenase-1 in complex with Heme bound to Carbon Monoxide
分子名称: CARBON MONOXIDE, HEME OXYGENASE-1, PROTOPORPHYRIN IX CONTAINING FE
著者Sugishima, M, Sakamoto, H, Omata, Y, Hayashi, S, Noguchi, M, Fukuyama, K.
登録日2002-06-10
公開日2003-09-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Ferrous and CO-, CN(-)-, and NO-Bound Forms of Rat Heme Oxygenase-1 (HO-1) in Complex with Heme: Structural Implications for Discrimination between CO and O(2) in HO-1.
Biochemistry, 42, 2003
6AI3
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Structure of the 328-692 fragment of FlhA (T490M)
分子名称: Flagellar biosynthesis protein FlhA
著者Ogawa, Y, Kinoshita, M, Minamino, T, Imada, K.
登録日2018-08-21
公開日2019-03-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Insights into the Substrate Specificity Switch Mechanism of the Type III Protein Export Apparatus.
Structure, 27, 2019
1AIP
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EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
分子名称: ELONGATION FACTOR TS, ELONGATION FACTOR TU
著者Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B.
登録日1997-04-22
公開日1997-10-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
5I3A
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Crystal Structure of tyrosinase from Bacillus megaterium with configuration A of hydroquinone inhibitor in the active site
分子名称: Tyrosinase, ZINC ION, benzene-1,4-diol
著者Kanteev, M, Deri, B, Adir, N, Fishman, A.
登録日2016-02-10
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The unravelling of the complex pattern of tyrosinase inhibition.
Sci Rep, 6, 2016
5I4Z
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Structure of apo OmoMYC
分子名称: CHLORIDE ION, GLYCEROL, Myc proto-oncogene protein, ...
著者Koelmel, W, Jung, L.A, Kuper, J, Eilers, M, Kisker, C.
登録日2016-02-13
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献OmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumors.
Oncogene, 36, 2017
4LVQ
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Crystal structure of the M. tuberculosis phosphate binding protein PstS3
分子名称: PHOSPHATE ION, Phosphate-binding protein PstS 3
著者Ferraris, D.M, Rizzi, M.
登録日2013-07-26
公開日2014-03-26
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the Mycobacterium tuberculosis phosphate binding protein PstS3.
Proteins, 82, 2014
4ZQR
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Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Mycobacterium tuberculosis
分子名称: GLYCEROL, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION, ...
著者Kim, Y, Makowska-Grzyska, M, Gu, M, Kavitha, M, Hedstrom, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-05-11
公開日2015-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.692 Å)
主引用文献Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.
Plos One, 10, 2015
7Q5A
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Lanreotide nanotube
分子名称: Lanreotide
著者Pieri, L, Wang, F, Arteni, A.A, Bressanelli, S, Egelman, E.H, Paternostre, M.
登録日2021-11-03
公開日2022-04-06
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Atomic structure of Lanreotide nanotubes revealed by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022

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件を2024-09-04に公開中

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