6R2H
 
 | | Crystal structure of Apo PinO from Porphyromonas gingivitis | | 分子名称: | GLYCEROL, HmuY protein | | 著者 | Antonyuk, S.V, Bielecki, M, Strange, R.W, Capper, M, Olczak, T, Olczak, M. | | 登録日 | 2019-03-17 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Prevotella intermedia produces two proteins homologous to Porphyromonas gingivalis HmuY but with different heme coordination mode.
Biochem.J., 477, 2020
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6F5W
 | | Photorhabdus asymbiotica lectin (PHL) in complex with propargyl-fucoside | | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, SODIUM ION, ... | | 著者 | Houser, J, Jancarikova, G, Wimmerova, M, Csavas, M, Borbas, A, Herczeg, M, Fujdiarova, E, Kover, E.K. | | 登録日 | 2017-12-04 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Synthesis of alpha-l-Fucopyranoside-Presenting Glycoclusters and Investigation of Their Interaction with Photorhabdus asymbiotica Lectin (PHL).
Chemistry, 24, 2018
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7ROC
 | | Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 7 | | 分子名称: | major capsid protein | | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | | 登録日 | 2021-07-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.
Cell, 185, 2022
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5YJE
 | | Crystal structure of HIRA(644-1017) | | 分子名称: | Protein HIRA, SULFATE ION | | 著者 | Sato, Y, Senda, M, Senda, T. | | 登録日 | 2017-10-10 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit
Nat Commun, 9, 2018
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7RO5
 | | Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 4 | | 分子名称: | major capsid protein | | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | | 登録日 | 2021-07-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.
Cell, 185, 2022
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7ROE
 | | Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 9 | | 分子名称: | major capsid protein | | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | | 登録日 | 2021-07-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.
Cell, 185, 2022
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6OGO
 | | Crystal structure of NDM-9 metallo-beta-lactamase | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Raczynska, J.E, Imiolczyk, B, Jaskolski, M. | | 登録日 | 2019-04-03 | | 公開日 | 2020-04-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Flexible loops of New Delhi metallo-beta-lactamase modulate its activity towards different substrates.
Int.J.Biol.Macromol., 158, 2020
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3KKQ
 | | Crystal structure of M-Ras P40D in complex with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein M-Ras | | 著者 | Muraoka, S, Shima, F, Liao, J, Ijiri, Y, Matsumoto, K, Ye, M, Inoue, T, Kataoka, T. | | 登録日 | 2009-11-06 | | 公開日 | 2010-06-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural basis for conformational dynamics of GTP-bound Ras protein
J.Biol.Chem., 285, 2010
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7ROD
 | | Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 8 | | 分子名称: | major capsid protein | | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | | 登録日 | 2021-07-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.
Cell, 185, 2022
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5FX5
 | | Novel inhibitors of human rhinovirus 3C protease | | 分子名称: | GLYCEROL, RHINOVIRUS 3C PROTEASE, TETRAETHYLENE GLYCOL, ... | | 著者 | Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q. | | 登録日 | 2016-02-24 | | 公開日 | 2016-06-22 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease.
Bioorg.Med.Chem.Lett., 26, 2016
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7ROB
 | | Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 6 | | 分子名称: | major capsid protein | | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | | 登録日 | 2021-07-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.
Cell, 185, 2022
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7RO6
 | | Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 5 | | 分子名称: | major capsid protein | | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | | 登録日 | 2021-07-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.
Cell, 185, 2022
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6BDJ
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7RO3
 | | Cryo-EM reconstruction of Sulfolobus monocaudavirus SMV1, symmetry 2 | | 分子名称: | major capsid protein | | 著者 | Wang, F, Cvirkaite-Krupovic, V, Krupovic, M, Egelman, E.H. | | 登録日 | 2021-07-30 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.
Cell, 185, 2022
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5FYQ
 | | Sirt2 in complex with a 13-mer trifluoroacetylated Ran peptide | | 分子名称: | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, RAN AA 31-43, SULFATE ION, ... | | 著者 | Knyphausen, P, de Boor, S, Scislowski, L, Extra, A, Baldus, L, Schacherl, M, Baumann, U, Neundorf, I, Lammers, M. | | 登録日 | 2016-03-09 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Insights Into Lysine-Deacetylation of Natively Folded Substrate Proteins by Sirtuins.
J.Biol.Chem., 291, 2016
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5D8T
 | | RNA octamer containing (S)-5' methyl, 2'-F U. | | 分子名称: | COBALT HEXAMMINE(III), RNA oligonucleotide containing (S)-C5'-Me-2'-FU | | 著者 | Harp, J.M, Egli, M. | | 登録日 | 2015-08-17 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides.
J.Org.Chem., 81, 2016
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6FER
 | | Crystal Structure of human DDR2 kinase in complex with 2-[4,5-difluoro-2-oxo-1'-(1H-pyrazolo[3,4-b]pyridine-5-carbonyl)spiro[indole-3,4'-piperidine]-1-yl]-N-(2,2,2-trifluoroethyl)acetamide | | 分子名称: | 2-[4,5-bis(fluoranyl)-2-oxidanylidene-1'-(1~{H}-pyrazolo[3,4-b]pyridin-5-ylcarbonyl)spiro[indole-3,4'-piperidine]-1-yl]-~{N}-[2,2,2-tris(fluoranyl)ethyl]ethanamide, Discoidin domain-containing receptor 2 | | 著者 | Stihle, M, Richter, H, Benz, J, Kuhn, B, Rudolph, M.G. | | 登録日 | 2018-01-03 | | 公開日 | 2018-11-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | | 主引用文献 | DNA-Encoded Library-Derived DDR1 Inhibitor Prevents Fibrosis and Renal Function Loss in a Genetic Mouse Model of Alport Syndrome.
Acs Chem.Biol., 14, 2019
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6EUT
 | | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (KSK67) | | 分子名称: | (3~{R})-8-cyclopropyl-7-[(4-methylnaphthalen-1-yl)methyl]-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. | | 登録日 | 2017-10-31 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
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6EUZ
 | | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK37) | | 分子名称: | (3~{R})-8-methoxy-7-(naphthalen-1-ylmethyl)-5-oxidanylidene-2,3-dihydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxylic acid, ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, ... | | 著者 | Begum, A, Hall, M, Grundstrom, C, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. | | 登録日 | 2017-10-31 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
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6R3W
 | | M.tuberculosis nitrobindin with a water molecule coordinated to the heme iron atom | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, UPF0678 fatty acid-binding protein-like protein ERS007657_00996 | | 著者 | De Simone, G, di Masi, A, Polticelli, F, Pesce, A, Nardini, M, Bolognesi, M, Ciaccio, C, Coletta, M, Turilli, E.S, Fasano, M, Tognaccini, L, Smulevich, G, Abbruzzetti, S, Viappiani, C, Bruno, S, Ascenzi, P. | | 登録日 | 2019-03-21 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Mycobacterial and Human Nitrobindins: Structure and Function.
Antioxid.Redox Signal., 33, 2020
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6EXM
 | | The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with a ring-fused 2-pyridone (MK202) | | 分子名称: | ISOPROPYL ALCOHOL, Listeriolysin positive regulatory factor A, SODIUM ION, ... | | 著者 | Grundstrom, C, Begum, A, Hall, M, Kulen, M, Lindgren, M, Johansson, J, Almqvist, F, Sauer, U.H, Sauer-Eriksson, A.E. | | 登録日 | 2017-11-08 | | 公開日 | 2018-05-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes.
J. Med. Chem., 61, 2018
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6AZD
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5Y2O
 | | Structure of PPARgamma ligand binding domain-pioglitazone complex | | 分子名称: | (5S)-5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma | | 著者 | Im, Y.J, Lee, M. | | 登録日 | 2017-07-26 | | 公開日 | 2017-12-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | | 主引用文献 | Structures of PPAR gamma complexed with lobeglitazone and pioglitazone reveal key determinants for the recognition of antidiabetic drugs
Sci Rep, 7, 2017
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6AZC
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5FN0
 | | Crystal structure of Pseudomonas fluorescens kynurenine-3- monooxygenase (KMO) in complex with GSK180 | | 分子名称: | 3-(5,6-DICHLORO-2-OXOBENZO[D]OXAZOL-3(2H)-YL)PROPANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, KYNURENINE 3-MONOOXYGENASE | | 著者 | Mole, D.J, Webster, S.P, Uings, I, Zheng, X, Binnie, M, Wilson, K, Hutchinson, J.P, Mirguet, O, Walker, A, Beaufils, B, Ancellin, N, Trottet, L, Beneton, V, Mowat, C.G, Wilkinson, M, Rowland, P, Haslam, C, McBride, A, Homer, N.Z.M, Baily, J.E, Sharp, M.G.F, Garden, O.J, Hughes, J, Howie, S.E.M, Holmes, D, Liddle, J, Iredale, J.P. | | 登録日 | 2015-11-10 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Kynurenine-3-Monooxygenase Inhibition Prevents Multiple Organ Failure in Rodent Models of Acute Pancreatitis.
Nat.Med. (N.Y.), 22, 2016
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