1ULD
| CGL2 in complex with blood group H type II | 分子名称: | alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, galectin-2 | 著者 | Walser, P.J, Haebel, P.W, Kuenzler, M, Kues, U, Aebi, M, Ban, N. | 登録日 | 2003-09-12 | 公開日 | 2004-04-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and Functional Analysis of the Fungal Galectin CGL2 STRUCTURE, 12, 2004
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1ULG
| CGL2 in complex with Thomsen-Friedenreich antigen | 分子名称: | beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, galectin-2 | 著者 | Walser, P.J, Haebel, P.W, Kuenzler, M, Kues, U, Aebi, M, Ban, N. | 登録日 | 2003-09-12 | 公開日 | 2004-04-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure and Functional Analysis of the Fungal Galectin CGL2 STRUCTURE, 12, 2004
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1V0E
| Endosialidase of Bacteriophage K1F | 分子名称: | ENDO-ALPHA-SIALIDASE, PHOSPHATE ION | 著者 | Stummeyer, K, Dickmanns, A, Muehlenhoff, M, Gerady-Schahn, R, Ficner, R. | 登録日 | 2004-03-28 | 公開日 | 2004-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F Nat.Struct.Mol.Biol., 12, 2005
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6TW9
| HumRadA22F in complex with CAM833 | 分子名称: | CALCIUM ION, DNA repair and recombination protein RadA, GLYCEROL, ... | 著者 | Fischer, G, Marsh, M.E, Scott, D.E, Coyne, A.G, Skidmore, J, Abell, C, Hyvonen, M. | 登録日 | 2020-01-12 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death. Cell Chem Biol, 28, 2021
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4V2T
| Membrane embedded pleurotolysin pore with 13 fold symmetry | 分子名称: | PLEUROTOLYSIN A, PLEUROTOLYSIN B | 著者 | Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R. | 登録日 | 2014-10-15 | 公開日 | 2015-02-18 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (11 Å) | 主引用文献 | Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13, 2015
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8QOY
| Capsular polysaccharide synthesis multienzyme of Actinobacillus Pleuropneumoniae serotype 3 | 分子名称: | SULFATE ION, TagF-like capsule polymerase Cps3D, ZINC ION | 著者 | Di Domenico, V, Litschko, C, Schulze, J, Bethe, A, Cifuente, J.O, Marina, A, Budde, I, Mast, T.A, Sulewska, M, Berger, M, Buettner, F, Gerardy-Schahn, R, Fiebig, T, Guerin, M.E. | 登録日 | 2023-09-29 | 公開日 | 2024-07-03 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Transition transferases prime bacterial capsule polymerization. Nat.Chem.Biol., 2024
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4LYM
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4LVA
| Fragment-based Identification of Amides Derived From trans-2-(Pyridin-3-yl)cyclopropanecarboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | 分子名称: | 1,2-ETHANEDIOL, N-(4-{[4-(pyrrolidin-1-yl)piperidin-1-yl]sulfonyl}benzyl)-2H-pyrido[4,3-e][1,2,4]thiadiazin-3-amine 1,1-dioxide, Nicotinamide phosphoribosyltransferase, ... | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | 登録日 | 2013-07-26 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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4M0U
| crystal structure of human PRS1 Q133P mutant | 分子名称: | Ribose-phosphate pyrophosphokinase 1, SULFATE ION | 著者 | Chen, P, Teng, M, Li, X. | 登録日 | 2013-08-02 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Crystal and EM Structures of Human Phosphoribosyl Pyrophosphate Synthase I (PRS1) Provide Novel Insights into the Disease-Associated Mutations Plos One, 10, 2015
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7ROY
| The structure of the Fem1B:FNIP1 complex | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Folliculin-interacting protein 1, Protein fem-1 homolog B, ... | 著者 | Gee, C.L, Mena, E.L, Manford, A.G, Rape, M. | 登録日 | 2021-08-02 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural basis and regulation of the reductive stress response. Cell, 184, 2021
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6TY7
| Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-1 | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Markova, K, Chaloupkova, R, Damborsky, J, Marek, M. | 登録日 | 2020-01-15 | 公開日 | 2021-01-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers Acs Catalysis, 11, 2021
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1V0F
| Endosialidase of Bacteriophage K1F in complex with oligomeric alpha-2,8-sialic acid | 分子名称: | ENDO-ALPHA-SIALIDASE, N-acetyl-alpha-neuraminic acid-(2-8)-N-acetyl-alpha-neuraminic acid, N-acetyl-beta-neuraminic acid, ... | 著者 | Stummeyer, K, Dickmanns, A, Muehlenhoff, M, Gerady-Schahn, R, Ficner, R. | 登録日 | 2004-03-28 | 公開日 | 2004-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Crystal Structure of the Polysialic Acid-Degrading Endosialidase of Bacteriophage K1F Nat.Struct.Mol.Biol., 12, 2005
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3SL9
| X-ray structure of Beta catenin in complex with Bcl9 | 分子名称: | 1,2-ETHANEDIOL, B-cell CLL/lymphoma 9 protein, Catenin beta-1, ... | 著者 | Gupta, D, Bienz, M. | 登録日 | 2011-06-24 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An intrinsically labile alpha-helix abutting the BCL9-binding site of beta-catenin is required for its inhibition by carnosic acid. Nat Commun, 3, 2012
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3SLA
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8QXY
| Xylanase from Bacillus circulans mutant E78Q bound to xylotriose | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endo-1,4-beta-xylanase, GLYCEROL, ... | 著者 | Chikunova, A, Saberi, M, Ubbink, M. | 登録日 | 2023-10-25 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | Bimodal substrate binding in the active site of the glycosidase BcX. Febs J., 2024
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8QY2
| Xylanase from Bacillus circulans mutant E78Q/F125A | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endo-1,4-beta-xylanase, GLYCEROL, ... | 著者 | Chikunova, A, Saberi, M, Ubbink, M. | 登録日 | 2023-10-25 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Bimodal substrate binding in the active site of the glycosidase BcX. Febs J., 2024
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8R86
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8QXZ
| Xylanase from Bacillus circulans mutant E78Q/Y69A | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Endo-1,4-beta-xylanase, ... | 著者 | Chikunova, A, Saberi, M, Ubbink, M. | 登録日 | 2023-10-25 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Bimodal substrate binding in the active site of the glycosidase BcX. Febs J., 2024
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8QY1
| Xylanase from Bacillus circulans mutant E78Q/Y69A bound to xylohexaose | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Endo-1,4-beta-xylanase, ... | 著者 | Chikunova, A, Saberi, M, Ubbink, M. | 登録日 | 2023-10-25 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Bimodal substrate binding in the active site of the glycosidase BcX. Febs J., 2024
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8QY0
| Xylanase from Bacillus circulans mutant E78Q/Y69A bound to xylotriose | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endo-1,4-beta-xylanase, ZINC ION, ... | 著者 | Chikunova, A, Saberi, M, Ubbink, M. | 登録日 | 2023-10-25 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Bimodal substrate binding in the active site of the glycosidase BcX. Febs J., 2024
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8QY3
| Xylanase from Bacillus circulans mutant E78Q/F125A bound to xylotriose | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Endo-1,4-beta-xylanase, ... | 著者 | Chikunova, A, Saberi, M, Ubbink, M. | 登録日 | 2023-10-25 | 公開日 | 2024-08-21 | 最終更新日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | 主引用文献 | Bimodal substrate binding in the active site of the glycosidase BcX. Febs J., 2024
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8R85
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3ST3
| Dreiklang - off state | 分子名称: | Dreiklang, PHOSPHATE ION | 著者 | Brakemann, T, Weber, G, Andresen, M, Stiel, A.C, Jakobs, S, Wahl, M.C. | 登録日 | 2011-07-08 | 公開日 | 2011-09-14 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching. Nat.Biotechnol., 29, 2011
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3G7Y
| Crystal structure of oxidized Ost6L | 分子名称: | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6 | 著者 | Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M. | 登録日 | 2009-02-11 | 公開日 | 2009-06-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.215 Å) | 主引用文献 | Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency. Proc.Natl.Acad.Sci.USA, 106, 2009
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7RLO
| Structure of the human eukaryotic translation initiation factor 2B (eIF2B) in complex with a viral protein NSs | 分子名称: | Non-structural protein NS-S, Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, ... | 著者 | Wang, L, Schoof, M, Cogan, J, Lawrence, R, Boone, M, Wuerth, J, Frost, M, Walter, P. | 登録日 | 2021-07-26 | 公開日 | 2021-12-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Viral evasion of the integrated stress response through antagonism of eIF2-P binding to eIF2B. Nat Commun, 12, 2021
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