3KWC
 
 | | Oxidized, active structure of the beta-carboxysomal gamma-Carbonic Anhydrase, CcmM | | 分子名称: | CHLORIDE ION, Carbon dioxide concentrating mechanism protein, ISOPROPYL ALCOHOL, ... | | 著者 | Kimber, M.S, Castel, S.E, Pena, K.L. | | 登録日 | 2009-12-01 | | 公開日 | 2010-02-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of the oxidative activation of the carboxysomal {gamma}-carbonic anhydrase, CcmM.
Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
6RAV
 | | Complement factor B protease domain in complex with the reversible inhibitor 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl)benzoic acid | | 分子名称: | 4-[(2~{S},4~{S})-4-ethoxy-1-[(5-methoxy-7-methyl-1~{H}-indol-4-yl)methyl]piperidin-2-yl]benzoic acid, Complement factor B, SULFATE ION, ... | | 著者 | Adams, C.M, Sellner, H, Ehara, T, Mac Sweeney, A, Crowley, M, Anderson, K, Karki, R, Mainolfi, N, Valeur, E, Sirockin, F, Gerhartz, B, Erbel, P, Hughes, N, Smith, T.M, Cumin, F, Argikar, U, Mogi, M, Sedrani, R, Wiesmann, C, Jaffee, B, Maibaum, J, Flohr, S, Harrison, R, Eder, J. | | 登録日 | 2019-04-08 | | 公開日 | 2019-04-17 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Small-molecule factor B inhibitor for the treatment of complement-mediated diseases.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
3L35
 | | PIE12 D-peptide against HIV entry | | 分子名称: | GP41 N-PEPTIDE, HIV ENTRY INHIBITOR PIE12 | | 著者 | Welch, B.D, Redman, J.S, Paul, S, Whitby, F.G, Weinstock, M.T, Reeves, J.D, Lie, Y.S, Eckert, D.M, Hill, C.P, Root, M.J, Kay, M.S. | | 登録日 | 2009-12-16 | | 公開日 | 2010-11-03 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance.
J.Virol., 84, 2010
|
|
3L1U
 | | Crystal structure of Calcium-bound GmhB from E. coli. | | 分子名称: | CALCIUM ION, D,D-heptose 1,7-bisphosphate phosphatase, ZINC ION | | 著者 | Sugiman-Marangos, S.N, Junop, M.S. | | 登録日 | 2009-12-14 | | 公開日 | 2010-01-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and kinetic characterization of the LPS biosynthetic enzyme D-alpha,beta-D-heptose-1,7-bisphosphate phosphatase (GmhB) from Escherichia coli.
Biochemistry, 49, 2010
|
|
3N1Z
 | | X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase T201S Mutant | | 分子名称: | FE (III) ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | 著者 | McCormick, M.S, Sazinsky, M.H, Lippard, S.J. | | 登録日 | 2010-05-17 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase.
J.Am.Chem.Soc., 132, 2010
|
|
3N20
 | | X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase T201V Mutant | | 分子名称: | FE (III) ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | 著者 | McCormick, M.S, Sazinsky, M.H, Lippard, S.J. | | 登録日 | 2010-05-17 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase.
J.Am.Chem.Soc., 132, 2010
|
|
7KGU
 | | Structure of 2Q1-Fab, an antibody selective for IDH2R140Q-HLA-B*07:02 | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Miller, M.S, Aytenfisu, T.Y, Wright, K.M, Gabelli, S.B. | | 登録日 | 2020-10-18 | | 公開日 | 2021-06-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens.
Nat Commun, 12, 2021
|
|
7UK4
 | | KS-AT di-domain of mycobacterial Pks13 with endogenous KS ligand bound | | 分子名称: | Polyketide synthase PKS13, UNKNOWN LIGAND | | 著者 | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | | 登録日 | 2022-03-31 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (1.94 Å) | | 主引用文献 | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Nat.Struct.Mol.Biol., 30, 2023
|
|
6RRA
 | | X-RAY STRUCTURE OF THE FERREDOXIN-NADP REDUCTASE FROM BRUCELLA OVIS IN COMPLEX WITH NADP | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Martinez-Julvez, M, Taleb, V, Medina, M. | | 登録日 | 2019-05-17 | | 公開日 | 2019-08-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Towards the competent conformation for catalysis in the ferredoxin-NADP+reductase from the Brucella ovis pathogen.
Biochim Biophys Acta Bioenerg, 1860, 2019
|
|
3N1Y
 | | X-ray Crystal Structure of Toluene/o-Xylene Monooxygenase Hydroxylase T201G Mutant | | 分子名称: | FE (III) ION, GLYCEROL, HEXAETHYLENE GLYCOL, ... | | 著者 | McCormick, M.S, Sazinsky, M.H, Lippard, S.J. | | 登録日 | 2010-05-17 | | 公開日 | 2010-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Active Site Threonine Facilitates Proton Transfer during Dioxygen Activation at the Diiron Center of Toluene/o-Xylene Monooxygenase Hydroxylase.
J.Am.Chem.Soc., 132, 2010
|
|
6RZU
 | | Structure of s-Mgm1 decorating the outer surface of tubulated lipid membranes in the GTPgammaS bound state | | 分子名称: | Putative mitochondrial dynamin protein | | 著者 | Faelber, K, Dietrich, L, Noel, J.K, Sanchez, R, Kudryashev, M, Kuelbrandt, W, Daumke, O. | | 登録日 | 2019-06-13 | | 公開日 | 2019-07-24 | | 最終更新日 | 2020-11-18 | | 実験手法 | ELECTRON MICROSCOPY (14.7 Å) | | 主引用文献 | Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Nature, 571, 2019
|
|
1ALV
 | | CALCIUM BOUND DOMAIN VI OF PORCINE CALPAIN | | 分子名称: | CALCIUM ION, CALPAIN | | 著者 | Narayana, S.V.L, Lin, G, Chattopadhyay, D, Maki, M. | | 登録日 | 1997-06-03 | | 公開日 | 1998-06-03 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of calcium bound domain VI of calpain at 1.9 A resolution and its role in enzyme assembly, regulation, and inhibitor binding.
Nat.Struct.Biol., 4, 1997
|
|
5ZJ6
 | | Crystal structure of HCK kinase complexed with a pyrrolo-pyrimidine inhibitor 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine | | 分子名称: | 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, Tyrosine-protein kinase HCK | | 著者 | Tomabechi, Y, Kukimoto-Niino, M, Shirouzu, M. | | 登録日 | 2018-03-19 | | 公開日 | 2018-06-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | Phosphorylated and non-phosphorylated HCK kinase domains produced by cell-free protein expression.
Protein Expr. Purif., 150, 2018
|
|
6KCJ
 | |
6K69
 | | Application of anti-helix antibodies in protein structure determination (9213-3LRH) | | 分子名称: | 3LRH intrabody, Engineered T4 lysozyme | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
5Z3E
 | | Glycosidase E335A | | 分子名称: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein | | 著者 | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | | 登録日 | 2018-01-05 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structural insights reveal the second base catalyst of isomaltose glucohydrolase.
Febs J., 289, 2022
|
|
6K68
 | | Application of anti-helix antibodies in protein structure determination (8420-3MNZ) | | 分子名称: | 3MNZ Variable heavy chain, 3MNZ Variable light chain, Protein A | | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | | 登録日 | 2019-06-01 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Application of antihelix antibodies in protein structure determination.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
3M58
 | | SET7/9 Y245A in complex with TAF10-K189me1 peptide and AdoHcy | | 分子名称: | Histone-lysine N-methyltransferase SETD7, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ... | | 著者 | Del Rizzo, P.A, Couture, J.-F, Roiko, M.S, Strunk, B.S, Brunzelle, J.S, Dirk, L.M, Houtz, R.L, Trievel, R.C. | | 登録日 | 2010-03-12 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.
J.Biol.Chem., 285, 2010
|
|
3M5A
 | | SET7/9 Y245A in complex with TAF10-K189me3 peptide and AdoHcy | | 分子名称: | COBALT (II) ION, GLYCEROL, Histone-lysine N-methyltransferase SETD7, ... | | 著者 | Del Rizzo, P.A, Couture, J.-F, Roiko, M.S, Strunk, B.S, Brunzelle, J.S, Dirk, L.M, Houtz, R.L, Trievel, R.C. | | 登録日 | 2010-03-12 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation.
J.Biol.Chem., 285, 2010
|
|
6UJV
 | | Model of the HIV-1 gp41 membrane-proximal external region, transmembrane domain and cytoplasmic tail (LLP2) | | 分子名称: | Envelope glycoprotein GP41 | | 著者 | Piai, A, Fu, Q, Cai, Y, Ghantous, F, Xiao, T, Shaik, M.M, Peng, H, Rits-Volloch, S, Liu, Z, Chen, W, Seaman, M.S, Chen, B, Chou, J.J. | | 登録日 | 2019-10-03 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis of transmembrane coupling of the HIV-1 envelope glycoprotein.
Nat Commun, 11, 2020
|
|
8P5G
 | | Kinase domain of wild type human ULK1 in complex with compound CCT241533 | | 分子名称: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, SODIUM ION, ... | | 著者 | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | | 登録日 | 2023-05-24 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.019 Å) | | 主引用文献 | Crystal structures of ULK1 in complex with KCGS compounds
To Be Published
|
|
8P5I
 | | Kinase domain of mutant human ULK1 in complex with compound XMD-17-51 | | 分子名称: | 5,11-dimethyl-2-[(1-piperidin-4-ylpyrazol-4-yl)amino]pyrimido[4,5-b][1,4]benzodiazepin-6-one, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | | 登録日 | 2023-05-24 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.829 Å) | | 主引用文献 | Crystal structures of ULK1 in complex with KCGS compounds
To Be Published
|
|
8P5L
 | | Kinase domain of mutant human ULK1 in complex with compound MRT67307 | | 分子名称: | MAGNESIUM ION, N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide, Serine/threonine-protein kinase ULK1 | | 著者 | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | | 登録日 | 2023-05-24 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.836 Å) | | 主引用文献 | Crystal structures of ULK1 in complex with KCGS compounds
To Be Published
|
|
8P5J
 | | Kinase domain of mutant human ULK1 in complex with compound WZ4003 | | 分子名称: | MAGNESIUM ION, SODIUM ION, Serine/threonine-protein kinase ULK1, ... | | 著者 | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | | 登録日 | 2023-05-24 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.164 Å) | | 主引用文献 | Crystal structures of ULK1 in complex with KCGS compounds
To Be Published
|
|
8P5H
 | | Kinase domain of mutant human ULK1 in complex with compound CCT241533 | | 分子名称: | 4-FLUORO-2-(4-{[(3S,4R)-4-(1-HYDROXY-1-METHYLETHYL)PYRROLIDIN-3-YL]AMINO}-6,7-DIMETHOXYQUINAZOLIN-2-YL)PHENOL, MAGNESIUM ION, SODIUM ION, ... | | 著者 | Battista, T, Semrau, M.S, Heroux, A, Lolli, G, Storici, P. | | 登録日 | 2023-05-24 | | 公開日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.941 Å) | | 主引用文献 | Crystal structures of ULK1 in complex with KCGS compounds
To Be Published
|
|
