8P5L

Kinase domain of mutant human ULK1 in complex with compound MRT67307

Summary for 8P5L

• Entry DOI: 10.2210/pdb8p5l/pdb
• Related: 8P5G
• Descriptor: Serine/threonine-protein kinase ULK1, N-{3-[(5-cyclopropyl-2-{[3-(morpholin-4-ylmethyl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: autophagy, unc-like 1 kinase, transferase, kcgs
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 65268.62

Authors

Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05, Last modification date: 2024-11-20)

• Primary citation: Battista, T.,Semrau, M.S.,Lolli, G.,Storici, P.; Crystal structures of ULK1 in complex with KCGS compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.836 Å)