8P5J

Kinase domain of mutant human ULK1 in complex with compound WZ4003

Summary for 8P5J

• Entry DOI: 10.2210/pdb8p5j/pdb
• Related: 8P5G
• Descriptor: Serine/threonine-protein kinase ULK1, ~{N}-[3-[5-chloranyl-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]oxyphenyl]propanamide, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: autophagy, unc-like 1 kinase, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 65307.77

Authors

Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05, Last modification date: 2024-11-06)

• Primary citation: Battista, T.,Semrau, M.S.,Lolli, G.,Storici, P.; Crystal structures of ULK1 in complex with KCGS compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.164 Å)