8P5J
Kinase domain of mutant human ULK1 in complex with compound WZ4003
Summary for 8P5J
Entry DOI | 10.2210/pdb8p5j/pdb |
Related | 8P5G |
Descriptor | Serine/threonine-protein kinase ULK1, ~{N}-[3-[5-chloranyl-2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]oxyphenyl]propanamide, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | autophagy, unc-like 1 kinase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 65307.77 |
Authors | Battista, T.,Semrau, M.S.,Heroux, A.,Lolli, G.,Storici, P. (deposition date: 2023-05-24, release date: 2024-06-05) |
Primary citation | Battista, T.,Semrau, M.S.,Lolli, G.,Storici, P. Crystal structures of ULK1 in complex with KCGS compounds To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.164 Å) |
Structure validation
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