4C02
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c02 by Molmil](/molmil-images/mine/4c02) | Crystal structure of human ACVR1 (ALK2) in complex with FKBP12.6 and dorsomorphin | 分子名称: | 1,2-ETHANEDIOL, 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine, ACTIVIN RECEPTOR TYPE-1, ... | 著者 | Williams, E, Riesebos, E, Vollmar, M, Krojer, T, Bradley, A, Shrestha, L, Kupinska, K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | 登録日 | 2013-07-31 | 公開日 | 2013-08-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Crystal Structure of Human Acvr1 (Alk2) in Complex with Fkbp12.6 And Dorsomorphin Ph D Thesis
|
|
4CDE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cde by Molmil](/molmil-images/mine/4cde) | Human DPP1 in complex with 4-amino-N-((1S)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-AZANYL-N-[(2S)-1-AZANYLIDENE-3-[4-(4-CYANOPHENYL)PHENYL]PROPAN-2-YL]OXANE-4-CARBOXAMIDE, CHLORIDE ION, ... | 著者 | Debreczeni, J, Edman, K, Furber, M, Tiden, A, Gardiner, P, Mete, T, Ford, R, Millichip, I, Stein, L, Mather, A, Kinchin, E, Luckhurst, C, Cage, P, Sanghanee, H, Breed, J, Wissler, L. | 登録日 | 2013-10-31 | 公開日 | 2014-03-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate. J.Med.Chem., 57, 2014
|
|
2KL2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kl2 by Molmil](/molmil-images/mine/2kl2) | NMR solution structure of A2LD1 (gi:13879369) | 分子名称: | AIG2-like domain-containing protein 1 | 著者 | Pedrini, B, Serrano, P, Mohanty, B, Geralt, M, Herrmann, T, Wuthrich, K, Wilson, I, Joint Center for Structural Genomics (JCSG) | 登録日 | 2009-06-30 | 公開日 | 2009-07-14 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Comparison of NMR and crystal structures highlights conformational isomerism in protein active sites. Acta Crystallogr.,Sect.F, 66, 2010
|
|
2KPI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kpi by Molmil](/molmil-images/mine/2kpi) | Solution NMR structure of Streptomyces coelicolor SCO3027 modeled with Zn+2 bound, Northeast Structural Genomics Consortium Target RR58 | 分子名称: | Uncharacterized protein SCO3027, ZINC ION | 著者 | Ramelot, T.A, Cort, J.R, Garcia, M, Yee, A, Arrowmith, C.H, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-15 | 公開日 | 2010-02-02 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of Streptomyces coelicolor SCO3027 modeled with Zn+2 bound, Northeast Structural Genomics Consortium Target RR58 To be Published
|
|
4CFQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4cfq by Molmil](/molmil-images/mine/4cfq) | Ca-bound truncated (delta13C) and C3S, C81S and C86S mutated S100A4 complexed with non-muscle myosin IIA | 分子名称: | CALCIUM ION, MYOSIN-9, PROTEIN S100-A4 | 著者 | Duelli, A, Kiss, B, Lundholm, I, Bodor, A, Radnai, L, Petoukhov, M, Svergun, D, Nyitray, L, Katona, G. | 登録日 | 2013-11-19 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 Through Conformational Activation. Plos One, 9, 2014
|
|
2KKL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kkl by Molmil](/molmil-images/mine/2kkl) | Solution NMR structure of FHA domain of Mb1858 from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR243C (24-155). | 分子名称: | Uncharacterized protein Mb1858 | 著者 | Yang, Y, Ramelot, T.A, Wang, D, Foote, E.L, Jiang, M, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-25 | 公開日 | 2009-07-07 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of FHA domain of Mb1858 from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR243C (24-155). To be Published
|
|
4BQJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bqj by Molmil](/molmil-images/mine/4bqj) | structure of HSP90 with an inhibitor bound | 分子名称: | 5-[2,4-dihydroxy-6-(4-nitrophenoxy)phenyl]-N-ethyl-1,2-oxazole-3-carboxamide, HEAT SHOCK PROTEIN HSP 90-ALPHA | 著者 | Casale, E, Brasca, M.G, Mantegani, S, Amboldi, N, Bindi, S, Caronni, D, Ceccarelli, W, Colombo, N, DePonti, A, Donati, D, Ermoli, A, Fachin, G, Felder, E.R, Ferguson, R.D, Fiorelli, C, Guanci, M, Isacchi, A, Pesenti, E, Polucci, P, Riceputi, L, Sola, F, Visco, C, Zuccotto, F, Fogliatto, G. | 登録日 | 2013-05-30 | 公開日 | 2013-10-23 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Nms-E973 as Novel, Selective and Potent Inhibitor of Heat Shock Protein 90 (Hsp90). Bioorg.Med.Chem., 21, 2013
|
|
2KS0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ks0 by Molmil](/molmil-images/mine/2ks0) | Solution NMR structure of the Q251Q8_DESHY(21-82) protein from Desulfitobacterium Hafniense, Northeast Structural Genomics Consortium Target DhR8C | 分子名称: | Uncharacterized protein | 著者 | Yang, Y, Ramelot, T.A, Cort, J.R, Wang, H, Ciccosanti, C, Foote, E.L, Jiang, M, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-12-23 | 公開日 | 2010-01-12 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Combining NMR and EPR methods for homodimer protein structure determination. J.Am.Chem.Soc., 132, 2010
|
|
4BS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bs9 by Molmil](/molmil-images/mine/4bs9) | Structure of the heterocyclase TruD | 分子名称: | TRUD, ZINC ION | 著者 | Koehnke, J, Bent, A.F, Zollman, D, Smith, K, Houssen, W.E, Zhu, X, Mann, G, Lebl, T, Scharff, R, Shirran, S, Botting, C.H, Jaspars, M, Schwarz-Linek, U, Naismith, J.H. | 登録日 | 2013-06-09 | 公開日 | 2013-11-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The Cyanobactin Heterocyclase Enzyme: A Processive Adenylase that Operates with a Defined Order of Reaction. Angew.Chem.Int.Ed.Engl., 52, 2013
|
|
2RH5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2rh5 by Molmil](/molmil-images/mine/2rh5) | Structure of Apo Adenylate Kinase from Aquifex Aeolicus | 分子名称: | Adenylate kinase | 著者 | Thai, V, Wolf-Watz, M, Fenn, T, Pozharski, E, Wilson, M.A, Petsko, G.A, Kern, D. | 登録日 | 2007-10-05 | 公開日 | 2007-12-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Intrinsic motions along an enzymatic reaction trajectory. Nature, 450, 2007
|
|
4C4Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c4z by Molmil](/molmil-images/mine/4c4z) | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A8 | 分子名称: | 1-ethyl-3-naphthalen-1-ylurea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | 登録日 | 2013-09-09 | 公開日 | 2014-10-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
4C4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c4y by Molmil](/molmil-images/mine/4c4y) | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A4 | 分子名称: | 1-(3-chlorophenyl)-3-(2-methoxyethyl)urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | 登録日 | 2013-09-09 | 公開日 | 2014-10-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
4C4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4c4x by Molmil](/molmil-images/mine/4c4x) | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with C9 | 分子名称: | 3-(3,4-dichlorophenyl)-1,1-dimethyl-urea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | 登録日 | 2013-09-09 | 公開日 | 2014-10-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
2K4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k4y by Molmil](/molmil-images/mine/2k4y) | NMR Structure of FeoA-like protein from Clostridium acetobutylicum: Northeast Structural Genomics Consortium Target CaR178 | 分子名称: | FeoA-like protein | 著者 | Singarapu, K, Wu, Y, Hua, J, Sukumaran, D, Zhao, L, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Baran, M.C, Swapna, G.V.T, Acton, T, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-06-20 | 公開日 | 2008-09-02 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of FeoA-like protein from Clostridium acetobutylicum: Northeast Structural Genomics Consortium Target CaR178 To be Published
|
|
2KNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2knu by Molmil](/molmil-images/mine/2knu) | Solution structure of the transmembrane proximal region of the hepatis C virus E1 glycoprotein | 分子名称: | Genome polyprotein | 著者 | Spadaccini, R, D'Errico, G, D'Alessio, V, Notomista, E, Bianchi, A, Merola, M, Picone, D. | 登録日 | 2009-09-04 | 公開日 | 2010-01-12 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural characterization of the transmembrane proximal region of the hepatitis C virus E1 glycoprotein Biochim.Biophys.Acta, 2009
|
|
4BWH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bwh by Molmil](/molmil-images/mine/4bwh) | |
4BMF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4bmf by Molmil](/molmil-images/mine/4bmf) | |
2KRF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2krf by Molmil](/molmil-images/mine/2krf) | NMR solution structure of the DNA binding domain of Competence protein A | 分子名称: | Transcriptional regulatory protein comA | 著者 | Hobbs, C.A, Bobay, B.G, Thompson, R.J, Perego, M, Cavanagh, J. | 登録日 | 2009-12-16 | 公開日 | 2010-04-07 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure and DNA-binding model of the DNA-binding domain of competence protein A. J.Mol.Biol., 398, 2010
|
|
4BY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4by9 by Molmil](/molmil-images/mine/4by9) | The structure of the Box CD enzyme reveals regulation of rRNA methylation | 分子名称: | 5'-R(*UP*CP*GP*CP*CP*CP*AP*UP*CP*AP*CP)-3', 50S RIBOSOMAL PROTEIN L7AE, FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERASE, ... | 著者 | Lapinaite, A, Simon, B, Skjaerven, L, Rakwalska-Bange, M, Gabel, F, Carlomagno, T. | 登録日 | 2013-07-18 | 公開日 | 2013-10-09 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of the Box C/D Enzyme Reveals Regulation of RNA Methylation. Nature, 502, 2013
|
|
2KEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2key by Molmil](/molmil-images/mine/2key) | Solution NMR structure of a domain from a putative phage integrase protein BF2284 from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR257C | 分子名称: | Putative phage integrase | 著者 | Mills, J.L, Sathyamoorthy, B, Sukumaran, D.K, Lee, D, Ciccosanti, C, Jiang, M, Xiao, R, Acton, T.B, Swapna, G.V.T, Rost, B, Nair, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-02-06 | 公開日 | 2009-04-14 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of a Domain from a Putative Phage Integrase Protein, BF2284, from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR257C To be Published
|
|
4H03
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h03 by Molmil](/molmil-images/mine/4h03) | Crystal structure of NAD+-Ia-actin complex | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Tsurumura, T, Oda, M, Nagahama, M, Tsuge, H. | 登録日 | 2012-09-07 | 公開日 | 2013-02-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
4H2T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h2t by Molmil](/molmil-images/mine/4h2t) | Crystal structure of Bradyrhizobium japonicum glycine:[carrier protein] ligase complexed with cognate carrier protein and an analogue of glycyl adenylate | 分子名称: | 4'-PHOSPHOPANTETHEINE, 5'-O-(glycylsulfamoyl)adenosine, Amino acid--[acyl-carrier-protein] ligase 1, ... | 著者 | Luic, M, Weygand-Durasevic, I, Ivic, N, Mocibob, M. | 登録日 | 2012-09-13 | 公開日 | 2013-03-06 | 最終更新日 | 2013-06-19 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Adaptation of aminoacyl-tRNA synthetase catalytic core to carrier protein aminoacylation. Structure, 21, 2013
|
|
2KBO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kbo by Molmil](/molmil-images/mine/2kbo) | Structure, interaction, and real-time monitoring of the enzymatic reaction of wild type APOBEC3G | 分子名称: | DNA dC->dU-editing enzyme APOBEC-3G, ZINC ION | 著者 | Furukawa, A, Nagata, T, Matsugami, A, Habu, Y, Sugiyama, R, Hayashi, F, Kobayashi, N, Yokoyama, S, Takaku, H, Katahira, M. | 登録日 | 2008-12-04 | 公開日 | 2009-02-03 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure, interaction and real-time monitoring of the enzymatic reaction of wild-type APOBEC3G Embo J., 28, 2009
|
|
2KLI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kli by Molmil](/molmil-images/mine/2kli) | Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED LIGHT-ABSORBING Form | 分子名称: | PHYCOCYANOBILIN, Sensor protein | 著者 | Cornilescu, C.C, Cornilescu, G, Ulijasz, A.T, Zhang, J, Rivera, M, Vierstra, R.D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2009-07-03 | 公開日 | 2009-11-03 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the photoconversion of a phytochrome to the activated Pfr form Nature, 463, 2010
|
|
2KNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2knh by Molmil](/molmil-images/mine/2knh) | The Solution structure of the eTAFH domain of AML1-ETO complexed with HEB peptide | 分子名称: | Protein CBFA2T1, Transcription factor 12 | 著者 | Park, S, Cierpicki, T, Tonelli, M, Bushweller, J.H. | 登録日 | 2009-08-25 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood, 113, 2009
|
|