4C02

Crystal structure of human ACVR1 (ALK2) in complex with FKBP12.6 and dorsomorphin

Summary for 4C02

• Entry DOI: 10.2210/pdb4c02/pdb
• Descriptor: ACTIVIN RECEPTOR TYPE-1, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1B, CITRATE ANION, ... (6 entities in total)
• Functional Keywords: transferase-isomerase complex, transferase, dorsomorphin, transferase/isomerase
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 2
• Total formula weight: 51916.42

Authors

Williams, E.,Riesebos, E.,Vollmar, M.,Krojer, T.,Bradley, A.,Shrestha, L.,Kupinska, K.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A. (deposition date: 2013-07-31, release date: 2013-08-07, Last modification date: 2023-12-20)

• Primary citation: Williams, E.,Riesebos, E.,Vollmar, M.,Krojer, T.,Bradley, A.,Shrestha, L.,Kupinska, K.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.; Crystal Structure of Human Acvr1 (Alk2) in Complex with Fkbp12.6 And Dorsomorphin; Ph D Thesis,

Experimental method

X-RAY DIFFRACTION (2.17 Å)