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PDB: 51787 件

1NGK
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Crystallographic Structure of Mycobacterium tuberculosis Hemoglobin O
分子名称: CYANIDE ION, Hemoglobin-like protein HbO, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Milani, M, Savard, P.-Y, Oullet, H, Ascenzi, P, Guertin, M, Bolognesi, M.
登録日2002-12-17
公開日2003-05-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献A TyrCD1/TrpG8 hydrogen bond network and a TyrB10-TyrCD1 covalent link shape the heme distal site of Mycobacterium tuberculosis hemoglobin O
Proc.Natl.Acad.Sci.USA, 100, 2003
1NHZ
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Crystal Structure of the Antagonist Form of Glucocorticoid Receptor
分子名称: 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODEC AHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE, GLUCOCORTICOID RECEPTOR, HEXANE-1,6-DIOL
著者Kauppi, B, Jakob, C, Farnegardh, M, Yang, J, Ahola, H, Alarcon, M, Calles, K, Engstrom, O, Harlan, J, Muchmore, S, Ramqvist, A.-K, Thorell, S, Ohman, L, Greer, J, Gustafsson, J.-A, Carlstedt-Duke, J, Carlquist, M.
登録日2002-12-20
公開日2003-05-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Three-dimensional Structures of Antagonistic and Agonistic Forms of the Glucocorticoid Receptor Ligand-binding Domain: RU-486 INDUCES A TRANSCONFORMATION THAT LEADS TO ACTIVE ANTAGONISM.
J.Biol.Chem., 278, 2003
4Y7E
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Crystal structure of beta-mannanase from Streptomyces thermolilacinus with mannohexaose
分子名称: CALCIUM ION, Endoglucanase, GLYCEROL, ...
著者Kumagai, Y, Yamashita, K, Okuyama, M, Hatanaka, T, Yao, M, Kimura, A.
登録日2015-02-14
公開日2015-09-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition
Febs J., 282, 2015
7JKM
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REGN1 Human Fab in complex with anti-Kappa VHH domain
分子名称: REGN1 Antibody Heavy Chain, REGN1 Antibody Light Chain, anti-Kappa VHH domain nanobody
著者Dennis, T.N, de la Cruz, M, Williams, J.C.
登録日2020-07-28
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Verification of a Fab binding nanobody for crystallization studies
To Be Published
7JLZ
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Crystal structure of 30S ribosomal A1408 methyltransferase from an uncultured bacterium (UncKam)
分子名称: 16S rRNA methylase, SULFATE ION
著者Nosrati, M, Conn, G.L.
登録日2020-07-30
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Roles of conserved tryptophans in substrate recognition and catalysis by the aminoglycoside-resistance 16S rRNA (m1A1408) rRNA methyltransferases
To be published
3FV1
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Crystal Structure of the human glutamate receptor, GluR5, ligand-binding core in complex with dysiherbaine in space group P1
分子名称: (2R,3aR,6S,7R,7aR)-2-[(2S)-2-amino-2-carboxyethyl]-6-hydroxy-7-(methylamino)hexahydro-2H-furo[3,2-b]pyran-2-carboxylic acid, GLYCEROL, Glutamate receptor, ...
著者Unno, M, Sasaki, M, Ikeda-Saito, M.
登録日2009-01-15
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Binding and Selectivity of the Marine Toxin Neodysiherbaine A and Its Synthetic Analogues to GluK1 and GluK2 Kainate Receptors.
J.Mol.Biol., 413, 2011
4DFL
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BU of 4dfl by Molmil
Crystal structure of spleen tyrosine kinase complexed with a sulfonamidopyrazine piperidine inhibitor
分子名称: 1,2-ETHANEDIOL, 3-amino-6-{3-[(methylsulfonyl)amino]phenyl}-N-(piperidin-4-ylmethyl)pyrazine-2-carboxamide, SULFATE ION, ...
著者Lopez, M, Segarra, V, Vidal, B, Wenzkowski, C, Jestel, A, Krapp, S, Blaesse, M, Nagel, S, Schreiner, P.
登録日2012-01-24
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Pyrazine-based Syk kinase inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
4BEG
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BU of 4beg by Molmil
Structure of Rv2140c, a phosphatidyl-ethanolamine binding protein from Mycobacterium tuberculosis in complex with sulphate
分子名称: GLYCEROL, PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN, SULFATE ION
著者Holton, S.J, Williams, M.
登録日2013-03-09
公開日2013-08-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural and Biochemical Characterization of Rv2140C, a Phosphatidylethanolamine-Binding Protein from Mycobacterium Tuberculosis.
FEBS Lett., 587, 2013
4AYL
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Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BOGT-METAL-INDEPENDENT GLYCOSYLTRANSFERASE, CALCIUM ION, ...
著者Thiyagarajan, N, Pham, T.T.K, Stinsonb, B, Sundriyala, A, Tumbale, P, Lizotte-Waniewskib, M, Brewb, K, Acharya, K.R.
登録日2012-06-21
公開日2012-12-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.919 Å)
主引用文献Structure of a Metal-Independent Bacterial Glycosyltransferase that Catalyzes the Synthesis of Histo-Blood Group a Antigen
Sci.Rep., 2, 2012
4YN3
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Crystal structure of Cucumisin complex with pro-peptide
分子名称: CHLORIDE ION, Cucumisin, DI(HYDROXYETHYL)ETHER, ...
著者Murayama, K, Kato-Murayama, M, Yokoyama, S, Arima, K, Shirouzu, M.
登録日2015-03-09
公開日2016-03-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis of cucumisin protease activity regulation by its propeptide
J. Biochem., 161, 2017
8AQH
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BU of 8aqh by Molmil
NanoLuc-Y94A luciferase mutant
分子名称: NanoLuc luciferase
著者Nemergut, M, Marek, M.
登録日2022-08-12
公開日2023-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
8AQ6
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NanoLuc luciferase with bound furimamide in surface allosteric site
分子名称: CHLORIDE ION, GLYCEROL, N-(3-Benzyl-5-phenylpyrazin-2-yl)-2-(furan-2-yl)acetamide, ...
著者Nemergut, M, Marek, M.
登録日2022-08-11
公開日2023-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
8AQI
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NanoLuc luciferase with bound coelenteramide in surface allosteric site
分子名称: CHLORIDE ION, N-[3-BENZYL-5-(4-HYDROXYPHENYL)PYRAZIN-2-YL]-2-(4-HYDROXYPHENYL)ACETAMIDE, NanoLuc luciferase, ...
著者Nemergut, M, Marek, M.
登録日2022-08-12
公開日2023-08-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Illuminating the mechanism and allosteric behavior of NanoLuc luciferase.
Nat Commun, 14, 2023
7K0T
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BU of 7k0t by Molmil
Cryo-EM structure of rabbit RyR1 in the presence of AMP-PCP in nanodisc
分子名称: PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, RyR1, ZINC ION
著者Nayak, A.R, Samso, M.
登録日2020-09-05
公開日2021-09-22
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7K0S
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Cryo-EM structure of rabbit RyR1 in the presence of Mg2+ and AMP-PCP in nanodisc
分子名称: MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2020-09-05
公開日2021-09-22
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor
Nat Commun, 15, 2024
4G9J
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BU of 4g9j by Molmil
Protein Ser/Thr phosphatase-1 in complex with cell-permeable peptide
分子名称: MANGANESE (II) ION, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, synthetic peptide
著者Sukackaite, R, Chatterjee, J, Beullens, M, Bollen, M, Koehn, M, Hart, D.J.
登録日2012-07-24
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Development of a Peptide that Selectively Activates Protein Phosphatase-1 in Living Cells.
Angew.Chem.Int.Ed.Engl., 51, 2012
4YAS
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HYDROXYNITRILE LYASE COMPLEXED WITH CHLORALHYDRATE
分子名称: PROTEIN (HYDROXYNITRILE LYASE), SULFATE ION, TRI-CHLORO-ACETALDEHYDE
著者Zuegg, J, Wagner, U.G, Gugganig, M, Kratky, C.
登録日1999-03-15
公開日1999-10-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structures of enzyme-substrate complexes of the hydroxynitrile lyase from Hevea brasiliensis.
Protein Sci., 8, 1999
4ABT
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Crystal structure of Type IIF restriction endonuclease NgoMIV with cognate uncleaved DNA
分子名称: 5'-D(*TP*GP*CP*GP*CP*CP*GP*GP*CP*GP*CP)-3', CALCIUM ION, TYPE-2 RESTRICTION ENZYME NGOMIV
著者Manakova, E.N, Grazulis, S, Zaremba, M, Tamulaitiene, G, Golovenko, D, Siksnys, V.
登録日2011-12-11
公開日2011-12-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structure of Type Iif Restriction Endonuclease Ngomiv with Cognate Uncleaved DNA
To be Published
5NUK
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BU of 5nuk by Molmil
Engineered beta-lactoglobulin: variant I56F-L39A-M107F in complex with chlorpromazine (LG-FAF-CLP)
分子名称: 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, Beta-lactoglobulin, CHLORIDE ION, ...
著者Loch, J.I, Bonarek, P, Tworzydlo, M, Lazinska, I, Szydlowska, J, Lewinski, K.
登録日2017-04-30
公開日2018-04-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The engineered beta-lactoglobulin with complementarity to the chlorpromazine chiral conformers.
Int. J. Biol. Macromol., 114, 2018
7JRK
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The Structure of BamE from Pseudomonas aeruginosa
分子名称: Outer membrane protein assembly factor BamE
著者Bi, M, Noinaj, N.
登録日2020-08-12
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献The crystal structure of BamE from Pseudomonas aeruginosa
To Be Published
5O1U
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Structure of wildtype T.maritima PDE (TM1595) with AMP and Mn2+
分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ...
著者Witte, G, Drexler, D, Mueller, M.
登録日2017-05-19
公開日2017-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima.
Structure, 25, 2017
7K1U
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Crystal Structure of SrtB-anchored Collagen-binding Adhesin Fragment (residues 206-565) from Clostridioides difficile strain 630
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Collagen-binding Adhesin
著者Minasov, G, Shuvalova, L, Rosas-Lemus, M, Wiersum, G, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2020-09-08
公開日2021-10-20
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of SrtB-anchored Collagen-binding Adhesin Fragment (residues 206-565) from Clostridioides difficile strain 630
To Be Published
1LHK
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ROLE OF PROLINE RESIDUES IN HUMAN LYSOZYME STABILITY: A SCANNING CALORIMETRIC STUDY COMBINED WITH X-RAY STRUCTURE ANALYSIS OF PROLINE MUTANTS
分子名称: HUMAN LYSOZYME
著者Inaka, K, Matsushima, M, Herning, T, Kuroki, R, Yutani, K, Kikuchi, M.
登録日1992-03-27
公開日1994-01-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Role of proline residues in human lysozyme stability: a scanning calorimetric study combined with X-ray structure analysis of proline mutants.
Biochemistry, 31, 1992
4YST
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BU of 4yst by Molmil
Structure of copper nitrite reductase from Geobacillus thermodenitrificans - 24.9 MGy
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, COPPER (II) ION, Nitrite reductase, ...
著者Fukuda, Y, Tse, K.M, Suzuki, M, Diederichs, K, Hirata, K, Nakane, T, Sugahara, M, Nango, E, Tono, K, Joti, Y, Kameshima, T, Song, C, Hatsui, T, Yabashi, M, Nureki, O, Matsumura, H, Inoue, T, Iwata, S, Mizohata, E.
登録日2015-03-17
公開日2016-02-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Redox-coupled structural changes in nitrite reductase revealed by serial femtosecond and microfocus crystallography
J.Biochem., 159, 2016
7KCZ
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CRYSTAL STRUCTURE OF RHESUS MACAQUE (MACACA MULATTA) IGG1 FC FRAGMENT- FC-GAMMA RECEPTOR III COMPLEX V158 MUTANT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IgG1 Fc, ...
著者Tolbert, W.D, Pazgier, M.
登録日2020-10-07
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Decoding human-macaque interspecies differences in Fc-effector functions: The structural basis for CD16-dependent effector function in Rhesus macaques.
Front Immunol, 13, 2022

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