7K1U

Crystal Structure of SrtB-anchored Collagen-binding Adhesin Fragment (residues 206-565) from Clostridioides difficile strain 630

Summary for 7K1U

• Entry DOI: 10.2210/pdb7k1u/pdb
• Descriptor: Collagen-binding Adhesin, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL (3 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, collagen-binding adhesin, cell adhesion
• Biological source: Clostridioides difficile
• Total number of polymer chains: 1
• Total formula weight: 39661.40

Authors

Minasov, G.,Shuvalova, L.,Rosas-Lemus, M.,Wiersum, G.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-09-08, release date: 2021-10-20, Last modification date: 2026-02-11)

Primary citation

Rosas-Lemus, M.,Dey, S.,Minasov, G.,Tan, K.,Anderson, S.M.,Brunzelle, J.,Nocadello, S.,Shabalin, I.,Filippova, E.,Halavaty, A.,Kim, Y.,Maltseva, N.,Osipiuk, J.,Minor, W.,Joachimiak, A.,Savchenko, A.,Anderson, W.F.,Satchell, K.J.F.
A high-throughput structural system biology approach to increase structure representation of proteins from Clostridioides difficile.
Microbiol Resour Announc, 12:e0050723-e0050723, 2023

PubMed Abstract: causes life-threatening gastrointestinal infections. It is a high-risk pathogen due to a lack of effective treatments, antimicrobial resistance, and a poorly conserved genomic core. Herein, we report 30 X-ray structures from a structure genomics pipeline spanning 13 years, representing 10.2% of the X-ray structures for this important pathogen.

PubMed: 37747257
DOI: 10.1128/MRA.00507-23

Experimental method

X-RAY DIFFRACTION (2.4 Å)