6GPY
 
 | | Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) in complex with AMPPNP | | 分子名称: | Heat shock protein HSP 90-alpha, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Tassone, G, Pozzi, C, Mangani, S, Botta, M. | | 登録日 | 2018-06-07 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
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3QD7
 | | Crystal structure of YdaL, a stand-alone small MutS-related protein from Escherichia coli | | 分子名称: | Uncharacterized protein ydaL | | 著者 | Gui, W.J, Qu, Q.H, Chen, Y.Y, Wang, M, Zhang, X.E, Bi, L.J, Jiang, T. | | 登録日 | 2011-01-18 | | 公開日 | 2011-06-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of YdaL, a stand-alone small MutS-related protein from Escherichia coli.
J.Struct.Biol., 174, 2011
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6GQ5
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4IRS
 | | Structure of the mouse CD1d-PyrC-alpha-GalCer-iNKT TCR complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Nemcovic, M, Zajonc, D.M. | | 登録日 | 2013-01-15 | | 公開日 | 2013-09-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Enhanced TCR footprint by a novel glycolipid increases NKT-dependent tumor protection.
J.Immunol., 191, 2013
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6GR3
 | | Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) variant K112R in complex with AMPPNP | | 分子名称: | AMP PHOSPHORAMIDATE, Heat shock protein HSP 90-alpha, MAGNESIUM ION | | 著者 | Tassone, G, Pozzi, C, Mangani, S, Botta, M. | | 登録日 | 2018-06-08 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
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6H6E
 | | PTC3 holotoxin complex from Photorhabdus luminecens in prepore state (TcdA1, TcdB2, TccC3) | | 分子名称: | TcdA1, TcdB2,TccC3 | | 著者 | Gatsogiannis, C, Merino, F, Roderer, D, Balchin, D, Schubert, E, Kuhlee, A, Hayer-Hartl, M, Raunser, S. | | 登録日 | 2018-07-27 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | | 主引用文献 | Tc toxin activation requires unfolding and refolding of a beta-propeller.
Nature, 563, 2018
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4IYL
 | | 30S ribosomal protein S15 from Campylobacter jejuni | | 分子名称: | 30S ribosomal protein S15 | | 著者 | Osipiuk, J, Nocek, B, Gu, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2013-01-28 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | 30S ribosomal protein S15 from Campylobacter jejuni
To be Published
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6GRN
 | | CELLOBIOHYDROLASE I (CEL7A) FROM Trichoderma reesei with S-dihydroxypropranolol in the active site | | 分子名称: | 2-[[(2~{S})-3-naphthalen-1-yloxy-2-oxidanyl-propyl]amino]propane-1,3-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... | | 著者 | Sandgren, M, Fagerstrom, A, Widmalm, G, Stahlberg, J. | | 登録日 | 2018-06-11 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Enantioselective Binding of Propranolol and Analogues Thereof to Cellobiohydrolase Cel7A.
Chemistry, 24, 2018
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3QF6
 | | Neutron structure of type-III Antifreeze Protein allows the reconstruction of AFP-ice interface | | 分子名称: | Type-3 ice-structuring protein HPLC 12 | | 著者 | Howard, E.I, Blakeley, M.P, Haertlein, M, Petit-Haertlein, I, Mitschler, A, Fisher, S.J, Cousido-Siah, A, Salvay, A.G, Popov, A, Muller-Dieckmann, C, Petrova, T, Podjarny, A. | | 登録日 | 2011-01-21 | | 公開日 | 2011-06-22 | | 最終更新日 | 2024-03-20 | | 実験手法 | NEUTRON DIFFRACTION (1.85 Å) | | 主引用文献 | Neutron structure of type-III antifreeze protein allows the reconstruction of AFP-ice interface.
J.Mol.Recognit., 24, 2011
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6GSF
 | | Solution structure of lipase binding domain LID1 of foldase from Pseudomonas aeruginosa | | 分子名称: | Lipase chaperone | | 著者 | Viegas, A, Jaeger, K.-E, Etzkorn, M, Gohlke, H, Verma, N, Dollinger, P, Kovacic, F. | | 登録日 | 2018-06-14 | | 公開日 | 2018-12-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation.
Sci Rep, 10, 2020
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6H76
 | | SiaP in complex with Neu5Ac (RT) | | 分子名称: | CESIUM ION, CHLORIDE ION, N-acetyl-beta-neuraminic acid, ... | | 著者 | Fischer, M, Darby, J.F, Brannigan, J.A, Turkenburg, J, Hubbard, R.E. | | 登録日 | 2018-07-30 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Water Networks Can Determine the Affinity of Ligand Binding to Proteins.
J.Am.Chem.Soc., 141, 2019
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4O7G
 | | Crystal Structure of Ascorbate-bound Cytochrome b561, crystal soaked in 1 M L-ascorbate for 40 minutes | | 分子名称: | ASCORBIC ACID, PROTOPORPHYRIN IX CONTAINING FE, Probable transmembrane ascorbate ferrireductase 2, ... | | 著者 | Lu, P, Ma, D, Yan, C, Gong, X, Du, M, Shi, Y. | | 登録日 | 2013-12-24 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.211 Å) | | 主引用文献 | Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
Proc.Natl.Acad.Sci.USA, 111, 2014
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3QFB
 | | Crystal structure of the human thioredoxin reductase-thioredoxin complex | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Thioredoxin, ... | | 著者 | Fritz-Wolf, K, Kehr, S, Stumpf, M, Rahlfs, S, Becker, K. | | 登録日 | 2011-01-21 | | 公開日 | 2011-07-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the human thioredoxin reductase-thioredoxin complex
Nat Commun, 2, 2011
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4IZH
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4ISQ
 | | Binding domain of Botulinum neurotoxin DC in complex with human synaptotagmin I | | 分子名称: | GLYCEROL, Neurotoxin, SULFATE ION, ... | | 著者 | Berntsson, R.P.-A, Peng, L, Svensson, L.M, Dong, M, Stenmark, P. | | 登録日 | 2013-01-17 | | 公開日 | 2013-08-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II.
Structure, 21, 2013
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3CJ7
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6GUR
 | | Siderophore hydrolase EstB from Aspergillus fumigatus in complex with TAFC | | 分子名称: | (~{Z})-5-[(1~{S},2~{S})-2-acetamido-1-oxidanyl-5-[oxidanyl(propanoyl)amino]pentoxy]-~{N},3-dimethyl-~{N}-oxidanyl-pent-2-enamide, CARBONATE ION, FE (III) ION, ... | | 著者 | Ecker, F, Haas, H, Groll, M, Huber, E.M. | | 登録日 | 2018-06-19 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Iron Scavenging in Aspergillus Species: Structural and Biochemical Insights into Fungal Siderophore Esterases.
Angew. Chem. Int. Ed. Engl., 57, 2018
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3QML
 | | The structural analysis of Sil1-Bip complex reveals the mechanism for Sil1 to function as a novel nucleotide exchange factor | | 分子名称: | 78 kDa glucose-regulated protein homolog, MAGNESIUM ION, Nucleotide exchange factor SIL1, ... | | 著者 | Yan, M, Li, J.Z, Sha, B.D. | | 登録日 | 2011-02-04 | | 公開日 | 2011-06-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structural analysis of the Sil1-Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor.
Biochem.J., 438, 2011
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3QNM
 | | Haloalkane Dehalogenase Family Member from Bacteroides thetaiotaomicron of Unknown Function | | 分子名称: | CHLORIDE ION, Haloacid dehalogenase-like hydrolase, MAGNESIUM ION | | 著者 | Matthew, M.W, Ramagopal, U.A, Toro, R, Dickey, M, Sauder, J.M, Poulter, C.D, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2011-02-08 | | 公開日 | 2011-03-30 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Haloalkane Dehalogenase Family Member from Bacteroides thetaiotaomicron of Unknown Function
To be Published
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3CJJ
 | | Crystal structure of human rage ligand-binding domain | | 分子名称: | ACETATE ION, Advanced glycosylation end product-specific receptor, ZINC ION | | 著者 | Koch, M, Dattilo, B.M, Schiefner, A, Diez, J, Chazin, W.J, Fritz, G. | | 登録日 | 2008-03-13 | | 公開日 | 2009-03-24 | | 最終更新日 | 2011-12-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural basis for ligand recognition and activation of RAGE.
Structure, 18, 2010
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6GF2
 | | The structure of the ubiquitin-like modifier FAT10 reveals a novel targeting mechanism for degradation by the 26S proteasome | | 分子名称: | Ubiquitin D | | 著者 | Aichem, A, Anders, S, Catone, N, Roessler, P, Stotz, S, Berg, A, Schwab, R, Scheuermann, S, Bialas, J, Schmidtke, G, Peter, C, Groettrup, M, Wiesner, S. | | 登録日 | 2018-04-29 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation.
Nat Commun, 9, 2018
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1HM3
 | | ACTIVE SITE OF CHONDROITINASE AC LYASE REVEALED BY THE STRUCTURE OF ENZYME-OLIGOSACCHARIDE COMPLEXES AND MUTAGENESIS | | 分子名称: | 2-O-methyl-beta-L-fucopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, CALCIUM ION, CHONDROITINASE AC, ... | | 著者 | Huang, W, Boju, L, Tkalec, L, Su, H, Yang, H.O, Gunay, N.S, Linhardt, R.J, Kim, Y.S, Matte, A, Cygler, M. | | 登録日 | 2000-12-04 | | 公開日 | 2001-05-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
Biochemistry, 40, 2001
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6GQB
 | | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | | 登録日 | 2018-06-07 | | 公開日 | 2018-07-11 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.
J. Mol. Biol., 430, 2018
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6GWP
 | | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) | | 分子名称: | Plasminogen Activator Inhibitor-1, VHH-2g-42, VHH-2w-64 | | 著者 | Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | | 登録日 | 2018-06-25 | | 公開日 | 2020-01-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction.
J.Thromb.Haemost., 18, 2020
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4J4Z
 | | Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, Designed serine hydrolase variant OSH55.4_H1.2, ... | | 著者 | Kuzin, A.P, Lew, S, Rajagopalan, S, Maglaqui, M, Xiao, R, Lee, D, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2013-02-07 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Crystal structure of the improved variant of the evolved serine hydrolase, OSH55.4_H1.2, bond with sulfate ion in the active site, Northeast Structural Genomics Consortium (NESG) Target OR301
To be Published
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