6G48
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![BU of 6g48 by Molmil](/molmil-images/mine/6g48) | Sporosarcina pasteurii urease inhibited by silver | 分子名称: | 1,2-ETHANEDIOL, HYDROXIDE ION, NICKEL (II) ION, ... | 著者 | Mazzei, L, Cianci, M, Ciurli, S. | 登録日 | 2018-03-27 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | The structure of urease inactivated by Ag(i): a new paradigm for enzyme inhibition by heavy metals. Dalton Trans, 47, 2018
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6K7C
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![BU of 6k7c by Molmil](/molmil-images/mine/6k7c) | Dimeric Shewanella violacea cytochrome c5 | 分子名称: | HEME C, NITRATE ION, Soluble cytochrome cA | 著者 | Yang, H, Yamanaka, M, Nagao, S, Yasuhara, K, Shibata, N, Higuchi, Y, Hirota, S. | 登録日 | 2019-06-07 | 公開日 | 2019-09-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Protein surface charge effect on 3D domain swapping in cells for c-type cytochromes. Biochim Biophys Acta Proteins Proteom, 1867, 2019
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6G4O
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![BU of 6g4o by Molmil](/molmil-images/mine/6g4o) | Non-aged form of Torpedo californica acetylcholinesterase inhibited by tabun analog NEDPA bound to uncharged reactivator 1 | 分子名称: | 2-[(~{E})-hydroxyiminomethyl]-6-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]pyridin-3-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | 著者 | Santoni, G, De la Mora, E, de Souza, J, Silman, I, Sussman, J, Baati, R, Weik, M, Nachon, F. | 登録日 | 2018-03-28 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents. J. Med. Chem., 61, 2018
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2E10
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4L66
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![BU of 4l66 by Molmil](/molmil-images/mine/4l66) | Crystal structure of Ribosome inactivating protein from Momordica balsamina with highly ordered water structure in the substrate binding site | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, rRNA N-glycosidase | 著者 | Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2013-06-12 | 公開日 | 2013-06-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of Ribosome inactivating protein from Momordica balsamina with highly ordered water structure in the substrate binding site To be Published
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6K7H
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![BU of 6k7h by Molmil](/molmil-images/mine/6k7h) | Cryo-EM structure of the human P4-type flippase ATP8A1-CDC50 (E1 state class2) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Cell cycle control protein 50A, ... | 著者 | Hiraizumi, M, Yamashita, K, Nishizawa, T, Nureki, O. | 登録日 | 2019-06-07 | 公開日 | 2019-08-28 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | 主引用文献 | Cryo-EM structures capture the transport cycle of the P4-ATPase flippase. Science, 365, 2019
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4LMU
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![BU of 4lmu by Molmil](/molmil-images/mine/4lmu) | Crystal structure of Pim1 in complex with the inhibitor Quercetin (resulting from displacement of SKF86002) | 分子名称: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, GLYCEROL, Serine/threonine-protein kinase pim-1 | 著者 | Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. | 登録日 | 2013-07-11 | 公開日 | 2014-02-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002. Acta Crystallogr.,Sect.D, 70, 2014
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2DXU
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![BU of 2dxu by Molmil](/molmil-images/mine/2dxu) | Crystal Structure Of Biotin Protein Ligase From Pyrococcus Horikoshii Complexed with Biotinyl-5'-AMP, Mutation R48A | 分子名称: | BIOTINYL-5-AMP, biotin--[acetyl-CoA-carboxylase] ligase | 著者 | Bagautdinov, B, Taketa, M, Matsuura, Y, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-08-30 | 公開日 | 2007-03-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate J.Biol.Chem., 283, 2008
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4L6U
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![BU of 4l6u by Molmil](/molmil-images/mine/4l6u) | Crystal structure of AF1868: Cmr1 subunit of the Cmr RNA silencing complex | 分子名称: | Putative uncharacterized protein | 著者 | Sun, J, Jeon, J.H, Shin, M, Shin, H.C, Oh, B.H, Kim, J.S. | 登録日 | 2013-06-12 | 公開日 | 2014-02-12 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure and CRISPR RNA-binding site of the Cmr1 subunit of the Cmr interference complex Acta Crystallogr.,Sect.D, 70, 2014
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3NAE
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![BU of 3nae by Molmil](/molmil-images/mine/3nae) | RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... | 著者 | Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. | 登録日 | 2010-06-01 | 公開日 | 2010-09-15 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
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3NAV
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![BU of 3nav by Molmil](/molmil-images/mine/3nav) | Crystal structure of an alpha subunit of tryptophan synthase from Vibrio cholerae O1 biovar El Tor str. N16961 | 分子名称: | 1,2-ETHANEDIOL, Tryptophan synthase alpha chain | 著者 | Nocek, B, Makowska-Grzyska, M, Kwon, K, Anderson, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-06-02 | 公開日 | 2010-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of an alpha subunit of tryptophan synthase from Vibrio cholerae O1 biovar El Tor str. N16961 To be Published
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8AES
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3NBH
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![BU of 3nbh by Molmil](/molmil-images/mine/3nbh) | Crystal structure of human RMI1C-RMI2 complex | 分子名称: | RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | 著者 | Wang, F, Yang, Y, Singh, T.R, Busygina, V, Guo, R, Wan, K, Wang, W, Sung, P, Meetei, A.R, Lei, M. | 登録日 | 2010-06-03 | 公開日 | 2010-09-22 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex. Structure, 18, 2010
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6KA0
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6G8M
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![BU of 6g8m by Molmil](/molmil-images/mine/6g8m) | Yeast 20S proteasome in complex with Cystargolide B Derivative 1 | 分子名称: | (2~{S},3~{R})-4-[[(2~{S})-3-methyl-1-[[(2~{S})-3-methyl-1-oxidanylidene-1-phenylmethoxy-butan-2-yl]amino]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanyl-4-oxidanylidene-2-propan-2-yl-butanoic acid, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Groll, M, Tello-Aburto, R. | 登録日 | 2018-04-09 | 公開日 | 2018-09-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Design, synthesis, and evaluation of cystargolide-based beta-lactones as potent proteasome inhibitors. Eur J Med Chem, 157, 2018
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8AEC
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![BU of 8aec by Molmil](/molmil-images/mine/8aec) | Structure of Compound 17 bound to CK2alpha | 分子名称: | 2-(5-bromanyl-6-chloranyl-1H-indazol-3-yl)ethanenitrile, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Brear, P, De Fusco, C, Atkinson, E, Iegre, I, Francis, N, Venkitaraman, A, Spring, D, Hyvonen, M. | 登録日 | 2022-07-12 | 公開日 | 2022-10-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | 主引用文献 | A fragment-based approach leading to the discovery of inhibitors of CK2 alpha with a novel mechanism of action. Rsc Med Chem, 13, 2022
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6JYF
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![BU of 6jyf by Molmil](/molmil-images/mine/6jyf) | Structure of light-state marine bacterial chloride importer, NM-R3, with Pulse laser (ND-1%) at 140K. | 分子名称: | CHLORIDE ION, Chloride pumping rhodopsin, OLEIC ACID, ... | 著者 | Yun, J.H, Ohki, M, Park, S.Y, Lee, W. | 登録日 | 2019-04-26 | 公開日 | 2020-03-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.004 Å) | 主引用文献 | Pumping mechanism of NM-R3, a light-driven bacterial chloride importer in the rhodopsin family. Sci Adv, 6, 2020
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5A2L
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![BU of 5a2l by Molmil](/molmil-images/mine/5a2l) | Crystal structure of scFv-SM3 in complex with APD-CGalNAc-RP | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, MODIFIED ANTIGEN TN, ... | 著者 | Martinez-Saez, N, Castro-Lopez, J, Valero-Gonzalez, J, Madariaga, D, Companon, I, Somovilla, V.J, Salvado, M, Asensio, J.L, Jimenez-Barbero, J, Avenoza, A, Busto, J.H, Bernardes, G.J.L, Peregrina, J.M, Hurtado-Guerrero, R, Corzana, F. | 登録日 | 2015-05-20 | 公開日 | 2015-06-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Deciphering the Non-Equivalence of Serine and Threonine O-Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an Anti-Muc1 Antibody. Angew.Chem.Int.Ed.Engl., 54, 2015
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4ZTX
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![BU of 4ztx by Molmil](/molmil-images/mine/4ztx) | Neurospora crassa cobalamin-independent methionine synthase complexed with Zn2+ | 分子名称: | Cobalamin-Independent Methionine synthase, GLYCEROL, NITRATE ION, ... | 著者 | Wheatley, R.W, Ng, K.K, Kapoor, M. | 登録日 | 2015-05-15 | 公開日 | 2015-12-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Fungal cobalamin-independent methionine synthase: Insights from the model organism, Neurospora crassa. Arch.Biochem.Biophys., 590, 2015
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4L70
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![BU of 4l70 by Molmil](/molmil-images/mine/4l70) | Human artd3 (parp3) - catalytic domain in complex with inhibitor ME0352 | 分子名称: | 3-(4-oxo-3,4-dihydroquinazolin-2-yl)-N-[(1S)-1-phenylpropyl]propanamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 3 | 著者 | Karlberg, T, Thorsell, A.G, Lindgren, A.E.G, Ekblad, T, Spjut, S, Andersson, C.D, Weigelt, J, Linusson, A, Elofsson, M, Schuler, H. | 登録日 | 2013-06-13 | 公開日 | 2014-02-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3. J.Med.Chem., 56, 2013
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4LB5
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8AEK
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![BU of 8aek by Molmil](/molmil-images/mine/8aek) | Structure of Compound 14 bound to CK2alpha | 分子名称: | 2-[5-(trifluoromethyl)-1H-indol-3-yl]ethanenitrile, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Brear, P, Fusco, C, Atkinson, E, Iegre, J, Francis-Newton, N, Venkotaraman, A, Spring, D, Hyvonen, M. | 登録日 | 2022-07-13 | 公開日 | 2022-10-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A fragment-based approach leading to the discovery of inhibitors of CK2 alpha with a novel mechanism of action. Rsc Med Chem, 13, 2022
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4ZUL
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![BU of 4zul by Molmil](/molmil-images/mine/4zul) | Structure ALDH7A1 complexed with alpha-aminoadipate | 分子名称: | 2-AMINOHEXANEDIOIC ACID, Alpha-aminoadipic semialdehyde dehydrogenase, TETRAETHYLENE GLYCOL, ... | 著者 | Luo, M, Tanner, J.J. | 登録日 | 2015-05-16 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1. Biochemistry, 54, 2015
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4LBB
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6FQR
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