4J9X
| Crystal structure of the complex of a hydroxyproline epimerase (TARGET EFI-506499, PSEUDOMONAS FLUORESCENS PF-5) with trans-4-hydroxy-l-proline | 分子名称: | 4-HYDROXYPROLINE, Proline racemase family protein, SODIUM ION | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-02-17 | 公開日 | 2013-03-13 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of the complex of a hydroxyproline epimerase (TARGET EFI-506499, PSEUDOMONAS FLUORESCENS PF-5) with trans-4-hydroxy-l-proline To be Published
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3PHD
| Crystal structure of human HDAC6 in complex with ubiquitin | 分子名称: | Histone deacetylase 6, Polyubiquitin, ZINC ION | 著者 | Dong, A, Qui, W, Ravichandran, M, Schuetz, A, Loppnau, P, Li, F, Mackenzie, F, Kozieradzki, I, Ouyang, H, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-03 | 公開日 | 2011-02-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini. J.Biol.Chem., 287, 2012
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6H7P
| Reductive Aminase from Aspergillus terreus in complex with NADPH4, cyclohexanone and allyl amine | 分子名称: | CYCLOHEXANONE, Reductive Aminase, [[(2~{R},3~{S},4~{R},5~{R})-5-[(3~{R})-3-aminocarbonylpiperidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, ... | 著者 | Sharma, M, Grogan, G, Mangas-Sanchez, J, Turner, N.J. | 登録日 | 2018-07-31 | 公開日 | 2019-04-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structure of Reductive Aminase from Aspergillus terreus Acs Catalysis, 2018
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1GT7
| L-rhamnulose-1-phosphate aldolase from Escherichia coli | 分子名称: | PHOSPHOGLYCOLOHYDROXAMIC ACID, RHAMNULOSE-1-PHOSPHATE ALDOLASE, ZINC ION | 著者 | Kroemer, M, Schulz, G.E. | 登録日 | 2002-01-14 | 公開日 | 2002-05-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The Structure of L-Rhamnulose-1-Phosphate Aldolase (Class II) Solved by Low-Resolution Sir Phasing and 20-Fold Ncs Averaging Acta Crystallogr.,Sect.D, 58, 2002
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6SSW
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3PW1
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4P9R
| Speciation of a group I intron into a lariat capping ribozyme (Heavy atom derivative) | 分子名称: | IRIDIUM HEXAMMINE ION, MAGNESIUM ION, RNA (189-MER) | 著者 | Meyer, M, Nielsen, H, Olieric, V, Roblin, P, Johansen, S.D, Westhof, E, Masquida, B. | 登録日 | 2014-04-04 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Speciation of a group I intron into a lariat capping ribozyme. Proc.Natl.Acad.Sci.USA, 111, 2014
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4PA1
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3DL7
| Aged Form of Mouse Acetylcholinesterase Inhibited by Tabun- Update | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, CHLORIDE ION, ... | 著者 | Carletti, E, Li, H, Li, B, Ekstrom, F, Nicolet, Y, Loiodice, M, Gillon, E, Froment, M.T, Lockridge, O, Schopfer, L.M, Masson, P, Nachon, F. | 登録日 | 2008-06-26 | 公開日 | 2008-12-02 | 最終更新日 | 2021-03-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation. J.Am.Chem.Soc., 130, 2008
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6EZ0
| Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding | 分子名称: | RNA (27-MER) | 著者 | Erat, M.C, Besic, E, Oberhuber, M, Johannsen, S, Sigel, R.K.O. | 登録日 | 2017-11-13 | 公開日 | 2018-01-03 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Specific phosphorothioate substitution within domain 6 of a group II intron ribozyme leads to changes in local structure and metal ion binding. J. Biol. Inorg. Chem., 23, 2018
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1N90
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6H59
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6GSJ
| Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAThr in the A-site | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Yusupov, M, Yusupova, G. | 登録日 | 2018-06-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Res., 46, 2018
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4P3O
| Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 2 | 分子名称: | (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, GLYCEROL, Threonine--tRNA ligase, ... | 著者 | Fang, P, Yu, X, Chen, K, Chen, X, Guo, M. | 登録日 | 2014-03-09 | 公開日 | 2015-03-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.505 Å) | 主引用文献 | Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun, 6, 2015
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3VOR
| Crystal Structure Analysis of the CofA | 分子名称: | CFA/III pilin | 著者 | Fukakusa, S, Kawahara, K, Nakamura, S, Iwasita, T, Baba, S, Nishimura, M, Kobayashi, Y, Honda, T, Iida, T, Taniguchi, T, Ohkubo, T. | 登録日 | 2012-02-06 | 公開日 | 2012-09-26 | 最終更新日 | 2013-07-31 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Structure of the CFA/III major pilin subunit CofA from human enterotoxigenic Escherichia coli determined at 0.90 A resolution by sulfur-SAD phasing Acta Crystallogr.,Sect.D, 68, 2012
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4PAW
| Structure of hypothetical protein HP1257. | 分子名称: | Orotate phosphoribosyltransferase, PHOSPHATE ION, THIOCYANATE ION, ... | 著者 | Battaile, K.P, Lam, R, Lam, K, Romanov, V, Jones, K, Soloveychik, M, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2014-04-10 | 公開日 | 2015-05-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structure of hypothetical protein HP1257. To Be Published
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6T13
| CRYSTAL STRUCTURE OF GLUCOCEREBROSIDASE IN COMPLEX WITH A PYRROLOPYRAZINE | 分子名称: | 1,2-ETHANEDIOL, 1-[4-[2-(4-methoxyphenyl)-5-methyl-pyrrolo[2,3-b]pyrazin-6-yl]piperidin-1-yl]ethanone, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Benz, J, Ehler, A, Hug, M, Huber, S, Rufer, A.C, Guba, W, Jagasia, R, Hofmann, E.C, Rodriguez Sarmiento, R.M. | 登録日 | 2019-10-03 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Novel beta-Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization. Angew.Chem.Int.Ed.Engl., 60, 2021
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3Q16
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6GW6
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4JDP
| Crystal structure of probable p-nitrophenyl phosphatase (pho2) (target EFI-501307) from Archaeoglobus fulgidus DSM 4304 with Magnesium bound | 分子名称: | CHLORIDE ION, MAGNESIUM ION, p-nitrophenyl phosphatase (Pho2) | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Al Obaidi, N, Stead, M, Love, J, Allen, K.N, Dunaway-Mariano, D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-02-25 | 公開日 | 2013-03-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Crystal structure of probable p-nitrophenyl phosphatase from Archaeoglobus fulgidus. To be Published
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1GYX
| The Crystal Structure of YdcE, a 4-Oxalocrotonate Tautomerase Homologue from Escherichia coli, Confirms the Structural Basis for Oligomer Diversity | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BENZOIC ACID, HYPOTHETICAL PROTEIN YDCE | 著者 | Almrud, J, Kern, A, Wang, S, Czerwinski, R, Johnson, W, Murzin, A, Hackert, M, Whitman, C. | 登録日 | 2002-04-30 | 公開日 | 2002-10-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The Crystal Structure of Ydce, a 4-Oxalocrotonate Tautomerase Homologue from Escherichia Coli, Confirms the Structural Basis for Oligomer Diversity Biochemistry, 41, 2002
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4JJT
| The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv | 分子名称: | ACETATE ION, Enoyl-CoA hydratase, GLYCEROL | 著者 | Tan, K, Holowicki, J, Endres, M, Kim, C.-Y, Kim, H, Hung, L.-W, Terwilliger, T.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2013-03-08 | 公開日 | 2013-03-27 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.496 Å) | 主引用文献 | The crystal structure of enoyl-CoA hydratase from Mycobacterium tuberculosis H37Rv To be Published
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2M64
| 1H, 13C and 15N Chemical Shift Assignments for Phl p 5a | 分子名称: | Phlp5 | 著者 | Goebl, C, Focke, M, Schrank, E, Madl, T, Kosol, S, Madritsch, C, Flicker, S, Valenta, R, Zangger, K, Tjandra, N. | 登録日 | 2013-03-21 | 公開日 | 2014-03-26 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Flexible IgE epitope-containing domains of Phl p 5 cause high allergenic activity. J. Allergy Clin. Immunol., 140, 2017
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3VQS
| Crystal structure of HCV NS5B RNA polymerase with a novel piperazine inhibitor | 分子名称: | (2R)-4-(5-cyclopropyl[1,3]thiazolo[4,5-d]pyrimidin-2-yl)-N-[3-fluoro-4-(trifluoromethoxy)benzyl]-1-{[4-(trifluoromethyl)phenyl]sulfonyl}piperazine-2-carboxamide, CHLORIDE ION, RNA-directed RNA polymerase | 著者 | Adachi, T, Doi, S, Ando, I, Sugimoto, K, Orita, T, Nomura, A, Kamada, M. | 登録日 | 2012-03-30 | 公開日 | 2012-08-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA Polymerase. Antimicrob.Agents Chemother., 56, 2012
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1HH1
| THE STRUCTURE OF HJC, A HOLLIDAY JUNCTION RESOLVING ENZYME FROM SULFOLOBUS SOLFATARICUS | 分子名称: | HOLLIDAY JUNCTION RESOLVING ENZYME HJC | 著者 | Bond, C.S, Kvaratskhelia, M, Richard, D, White, M.F, Hunter, W.N. | 登録日 | 2000-12-18 | 公開日 | 2001-04-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of Hjc, a Holliday Junction Resolvase, from Sulfolobus Solfataricus Proc.Natl.Acad.Sci.USA, 98, 2001
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