Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 51689 件
5J4T
DownloadVisualize
BU of 5j4t by Molmil
Structure of tetrameric jacalin complexed with GlcNAc beta-(1,3) Gal-beta-OMe
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-methyl beta-D-galactopyranoside, Agglutinin alpha chain, ...
著者Abhinav, K.V, Sharma, K, Surolia, A, Vijayan, M.
登録日2016-04-01
公開日2017-02-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Distortion of the ligand molecule as a strategy for modulating binding affinity: Further studies involving complexes of jacalin with beta-substituted disaccharides.
IUBMB Life, 69, 2017
8AR8
DownloadVisualize
BU of 8ar8 by Molmil
Bovine glutamate dehydrogenase in complex with ADP at 2.4 A resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamate dehydrogenase (NAD(P)(+))
著者Aleshin, V.A, Bellinzoni, M.
登録日2022-08-15
公開日2022-10-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for the Binding of Allosteric Activators Leucine and ADP to Mammalian Glutamate Dehydrogenase.
Int J Mol Sci, 23, 2022
7QNI
DownloadVisualize
BU of 7qni by Molmil
CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT L259V
分子名称: CITRIC ACID, Lactaldehyde reductase
著者Sridhar, S, Kiema, T.R, Wierenga, R.K, Widersten, M.
登録日2021-12-20
公開日2022-10-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics.
Febs J., 290, 2023
8CXC
DownloadVisualize
BU of 8cxc by Molmil
Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
分子名称: 3F2 Antibody heavy chain, 3F2 Antibody light chain, Mesothelin, ...
著者Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E.
登録日2022-05-20
公開日2023-06-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (4.31 Å)
主引用文献Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
5T71
DownloadVisualize
BU of 5t71 by Molmil
Human carboanhydrase F131C_C206S double mutant in complex with SA-2
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(HYDROXYMERCURY)BENZOIC ACID, 4-[(E)-diazenyl]benzene-1-sulfonamide, ...
著者DuBay, K.H, Iwan, K, Osorio-Planes, L, Geissler, P, Groll, M, Trauner, D, Broichhagen, J.
登録日2016-09-02
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity.
ACS Chem. Biol., 13, 2018
5J5I
DownloadVisualize
BU of 5j5i by Molmil
X-Ray Crystal Structure of Acetylcholine Binding Protein (AChBP) in Complex with 4-(2-amino-6-{bis[(pyridin-2-yl)methyl]amino}pyrimidin-4-yl)phenol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-amino-6-{bis[(pyridin-2-yl)methyl]amino}pyrimidin-4-yl)phenol, Acetylcholine-binding protein, ...
著者Kaczanowska, K, Harel, M, Camacho Hernandez, G.A, Taylor, P.
登録日2016-04-02
公開日2017-03-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.326 Å)
主引用文献Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins.
J. Am. Chem. Soc., 139, 2017
5GSM
DownloadVisualize
BU of 5gsm by Molmil
Glycoside hydrolase B with product
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Watanabe, M, Kamachi, S, Mine, S.
登録日2016-08-16
公開日2017-02-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Glycoside hydrolase B with product
To Be Published
5T78
DownloadVisualize
BU of 5t78 by Molmil
Crystal structure of therapeutic mAB AR20.5 in complex with MUC1 peptide
分子名称: 2-acetamido-2-deoxy-beta-D-galactopyranose, Fab Fragment - AR20.5 - Heavy chain, Fab fragment AR20.5 - Light Chain, ...
著者Brooks, C.L, Movahedin, M.
登録日2016-09-02
公開日2017-01-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.
Glycobiology, 27, 2017
5T7K
DownloadVisualize
BU of 5t7k by Molmil
X-ray crystal structure of AA13 LPMO
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AoAA13, ZINC ION
著者Frandsen, K.E.H, Poulsen, J.-C.N, Tovborg, M, Johansen, K.S, Lo Leggio, L.
登録日2016-09-05
公開日2017-01-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Learning from oligosaccharide soaks of crystals of an AA13 lytic polysaccharide monooxygenase: crystal packing, ligand binding and active-site disorder.
Acta Crystallogr D Struct Biol, 73, 2017
7QEA
DownloadVisualize
BU of 7qea by Molmil
Crystal structure of fluorescein-di-Beta-D-glucuronide bound to a mutant of SN243 (D415A)
分子名称: (2~{S},3~{S},4~{S},5~{R},6~{S})-3,4,5-tris(oxidanyl)-6-[(1~{R})-6'-oxidanyl-3-oxidanylidene-spiro[2-benzofuran-1,9'-xanthene]-3'-yl]oxy-oxane-2-carboxylic acid, ACETATE ION, SN243, ...
著者Neun, S, Brear, P, Campbell, E, Omari, K, Wagner, O, Hyvonen, M, Hollfelder, F.
登録日2021-12-01
公開日2022-10-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Functional metagenomic screening identifies an unexpected beta-glucuronidase.
Nat.Chem.Biol., 18, 2022
7QNJ
DownloadVisualize
BU of 7qnj by Molmil
CRYSTAL STRUCTURE OF E.coli ALCOHOL DEHYDROGENASE - FucO MUTANT F254I COMPLEXED WITH FE, NAD+, AND GLYCEROL
分子名称: FE (III) ION, GLYCEROL, Lactaldehyde reductase, ...
著者Sridhar, S, Kiema, T.R, Wierenga, R.K, Widersten, M.
登録日2021-12-20
公開日2022-10-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structures of lactaldehyde reductase, FucO, link enzyme activity to hydrogen bond networks and conformational dynamics.
Febs J., 290, 2023
7QG4
DownloadVisualize
BU of 7qg4 by Molmil
Apo crystal structure of a mutant of SN243 (D415N)
分子名称: SN243, SULFATE ION, ZINC ION
著者Neun, S, Brear, P, Campbell, E, Omari, K, Wagner, O, Hyvonen, M, Hollfelder, F.
登録日2021-12-07
公開日2022-10-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Functional metagenomic screening identifies an unexpected beta-glucuronidase.
Nat.Chem.Biol., 18, 2022
5TAC
DownloadVisualize
BU of 5tac by Molmil
Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
分子名称: CALCIUM ION, LYSINE, Thermolysin, ...
著者Dong, M, Bahnson, B.J.
登録日2016-09-09
公開日2017-08-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Conformational Sampling Differences across the Arrhenius Plot Biphasic Break Point at Ambient Temperature in the Enzyme Thermolysin
To Be Published
8CYH
DownloadVisualize
BU of 8cyh by Molmil
Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A12 antibody heavy chain, A12 antibody light chain, ...
著者Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E.
登録日2022-05-23
公開日2023-06-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
5T63
DownloadVisualize
BU of 5t63 by Molmil
The HhoA protease from Synechocystis sp. PCC 6803
分子名称: ALA-ALA-ALA-ALA, MAGNESIUM ION, Putative serine protease HhoA
著者Persson, K, Hall, M, Funk, C.
登録日2016-09-01
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The HhoA protease from Synechocystis sp. PCC 6803 - Novel insights into structure and activity regulation.
J. Struct. Biol., 198, 2017
5TDW
DownloadVisualize
BU of 5tdw by Molmil
Set3 PHD finger in complex with histone H3K4me3
分子名称: SET domain-containing protein 3, SODIUM ION, ZINC ION, ...
著者Andrews, F.H, Ali, M, Kutateladze, T.G.
登録日2016-09-19
公開日2016-10-19
最終更新日2017-06-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Insight into Recognition of Methylated Histone H3K4 by Set3.
J. Mol. Biol., 429, 2017
4LA5
DownloadVisualize
BU of 4la5 by Molmil
Crystal structure of 2-methylisoborneol synthase from Streptomyces coelicolor A3(2)
分子名称: 2-methylisoborneol synthase
著者Koksal, M, Christianson, D.W.
登録日2013-06-19
公開日2013-07-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献Unexpected reactivity of 2-fluorolinalyl diphosphate in the active site of crystalline 2-methylisoborneol synthase.
Biochemistry, 52, 2013
7QEF
DownloadVisualize
BU of 7qef by Molmil
Crystal structure of para-nitrophenyl-Beta-D-glucuronide bound to a mutant of SN243 (D415A)
分子名称: 4-nitrophenyl beta-D-glucopyranosiduronic acid, ACETATE ION, SN243, ...
著者Neun, S, Brear, P, Campbell, E, Omari, K, Wagner, O, Hyvonen, M, Hollfelder, F.
登録日2021-12-02
公開日2022-10-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Functional metagenomic screening identifies an unexpected beta-glucuronidase.
Nat.Chem.Biol., 18, 2022
3AOX
DownloadVisualize
BU of 3aox by Molmil
X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802
分子名称: 1,2-ETHANEDIOL, 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, ALK tyrosine kinase receptor
著者Nagel, S, Moertl, M, Jestel, A, Fukami, T.A.
登録日2010-10-08
公開日2011-05-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant
Cancer Cell, 19, 2011
5T69
DownloadVisualize
BU of 5t69 by Molmil
The HhoA protease from Synechocystis sp. PCC 6803, active site mutant
分子名称: ACETATE ION, MAGNESIUM ION, Putative serine protease HhoA
著者Persson, K, Hall, M, Funk, C.
登録日2016-09-01
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The HhoA protease from Synechocystis sp. PCC 6803 - Novel insights into structure and activity regulation.
J. Struct. Biol., 198, 2017
8CZ8
DownloadVisualize
BU of 8cz8 by Molmil
Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
分子名称: Mesothelin, cleaved form, SULFATE ION, ...
著者Bandaranayake, A.D, Rupert, P.B, Lin, I, Pilat, K, Ruff, R.O, Friend, D.J, Chan, M.K, Clarke, M, Carter, J, Meshinchi, S, Mehlin, C, Olson, J.M, Strong, R.K, Correnti, C.E.
登録日2022-05-24
公開日2023-06-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Novel mesothelin antibodies enable crystallography of the intact mesothelin ectodomain and engineering of potent, T cell-engaging bispecific therapeutics
Front. Drug Discov., 3, 2023
5GO8
DownloadVisualize
BU of 5go8 by Molmil
Linear tetra-ubiquitin
分子名称: D-ubiquitin, ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-26
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
1BK5
DownloadVisualize
BU of 1bk5 by Molmil
KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE
分子名称: COBALT (II) ION, KARYOPHERIN ALPHA
著者Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J.
登録日1998-07-14
公開日1999-01-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha.
Cell(Cambridge,Mass.), 94, 1998
5GOD
DownloadVisualize
BU of 5god by Molmil
Lys27-linked di-ubiquitin
分子名称: D-ubiquitin, MAGNESIUM ION, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-26
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5T6O
DownloadVisualize
BU of 5t6o by Molmil
Structure of the catalytic domain of the class I polyhydroxybutyrate synthase from Cupriavidus necator
分子名称: Poly-beta-hydroxybuterate polymerase, SULFATE ION
著者Wittenborn, E.C, Jost, M, Drennan, C.L.
登録日2016-09-01
公開日2016-10-26
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the Catalytic Domain of the Class I Polyhydroxybutyrate Synthase from Cupriavidus necator.
J.Biol.Chem., 291, 2016

224572

件を2024-09-04に公開中

PDB statisticsPDBj update infoContact PDBjnumon