5T71

Human carboanhydrase F131C_C206S double mutant in complex with SA-2

Summary for 5T71

• Entry DOI: 10.2210/pdb5t71/pdb
• Related: 2VVA
• Descriptor: Carbonic anhydrase 2, ZINC ION, 4-(HYDROXYMERCURY)BENZOIC ACID, ... (6 entities in total)
• Functional Keywords: photopharmacology; carbonic anhydrase; photochromic tethered ligand; azobenzene; computational screening, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 30062.58

Authors

DuBay, K.H.,Iwan, K.,Osorio-Planes, L.,Geissler, P.,Groll, M.,Trauner, D.,Broichhagen, J. (deposition date: 2016-09-02, release date: 2017-09-06, Last modification date: 2024-01-17)

• Primary citation: DuBay, K.H.,Iwan, K.,Osorio-Planes, L.,Geissler, P.L.,Groll, M.,Trauner, D.,Broichhagen, J.; A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity.; ACS Chem. Biol., 13:793-800, 2018; PubMed: 29357237; DOI: 10.1021/acschembio.7b00862

Experimental method

X-RAY DIFFRACTION (1.3 Å)