5T71
Human carboanhydrase F131C_C206S double mutant in complex with SA-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29229.0 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (Human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | 4-(HYDROXYMERCURY)BENZOIC ACID | non-polymer | 338.7 | 1 | Chemie (HGB) | |||
| 4 | D (A) | 4-[(E)-diazenyl]benzene-1-sulfonamide | non-polymer | 185.2 | 1 | Chemie (75W) | |||
| 5 | E, F (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 6 | G (A) | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Cys 130 | Phe 130 | engineered mutation |
| Ser 205 | Cys 205 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29229.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 833.6 | |
| All* | Total formula weight | 30062.6 |
