1X6D
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![BU of 1x6d by Molmil](/molmil-images/mine/1x6d) | Solution structures of the PDZ domain of human Interleukin-16 | Descriptor: | Interleukin-16 | Authors: | Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-17 | Release date: | 2005-11-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the PDZ domain of human Interleukin-16 To be Published
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1X6F
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![BU of 1x6f by Molmil](/molmil-images/mine/1x6f) | Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 462 | Descriptor: | ZINC ION, Zinc finger protein 462 | Authors: | Sato, M, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-17 | Release date: | 2005-11-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the C2H2 type zinc finger domain of human Zinc finger protein 462 To be Published
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6V1V
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![BU of 6v1v by Molmil](/molmil-images/mine/6v1v) | VIP3B (VIP3B_2160) adapted for crystallization | Descriptor: | Vegetative insecticidal protein | Authors: | Evdokimov, A.G, Zheng, M, Moshiri, F, Haas, J, Lowder, C. | Deposit date: | 2019-11-21 | Release date: | 2019-12-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.189 Å) | Cite: | Crystal structure of a Vip3B family insecticidal protein reveals a new fold and a unique tetrameric assembly. Protein Sci., 29, 2020
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7OBA
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![BU of 7oba by Molmil](/molmil-images/mine/7oba) | Cryo-EM structure of human RNA Polymerase I in complex with RRN3 | Descriptor: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | Authors: | Misiaszek, A.D, Girbig, M, Mueller, C.W. | Deposit date: | 2021-04-21 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
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6PJL
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![BU of 6pjl by Molmil](/molmil-images/mine/6pjl) | HIV-1 Protease NL4-3 WT in Complex with LR3-95 | Descriptor: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,4S,5S)-4-hydroxy-5-{[N-(methoxycarbonyl)-L-alloisoleucyl]amino}-1,6-diphenylhexan-2-yl]carbamate, Protease NL4-3, SULFATE ION | Authors: | Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. | Deposit date: | 2019-06-28 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.993 Å) | Cite: | Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere. J.Med.Chem., 63, 2020
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7OBB
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![BU of 7obb by Molmil](/molmil-images/mine/7obb) | Cryo-EM structure of human RNA Polymerase I Open Complex | Descriptor: | DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... | Authors: | Misiaszek, A.D, Girbig, M, Mueller, C.W. | Deposit date: | 2021-04-21 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
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7OB9
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![BU of 7ob9 by Molmil](/molmil-images/mine/7ob9) | Cryo-EM structure of human RNA Polymerase I in elongation state | Descriptor: | DNA non-template strand, DNA template strand, DNA-directed RNA polymerase I subunit RPA1, ... | Authors: | Misiaszek, A.D, Girbig, M, Mueller, C.W. | Deposit date: | 2021-04-21 | Release date: | 2021-12-08 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of human RNA polymerase I. Nat.Struct.Mol.Biol., 28, 2021
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6V40
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![BU of 6v40 by Molmil](/molmil-images/mine/6v40) | Structure of Salmonella Typhi TtsA | Descriptor: | 2,6-DIAMINOPIMELIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PG_binding_3 domain-containing protein | Authors: | Galan, J.E, Lara-Tejero, M. | Deposit date: | 2019-11-27 | Release date: | 2020-01-29 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | Mechanisms of substrate recognition by a typhoid toxin secretion-associated muramidase. Elife, 9, 2020
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3O73
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![BU of 3o73 by Molmil](/molmil-images/mine/3o73) | Crystal structure of quinone reductase 2 in complex with the indolequinone MAC627 | Descriptor: | 5-[(4-aminobutyl)amino]-1,2-dimethyl-3-[(4-nitrophenoxy)methyl]-1H-indole-4,7-dione, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | Authors: | Dufour, M, Yan, C, Colucci, M.A, Siegel, D, Li, Y, De Matteis, C.I, Ross, D, Moody, C.J. | Deposit date: | 2010-07-30 | Release date: | 2011-05-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition. Chembiochem, 12, 2011
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1TFE
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![BU of 1tfe by Molmil](/molmil-images/mine/1tfe) | DIMERIZATION DOMAIN OF EF-TS FROM T. THERMOPHILUS | Descriptor: | ELONGATION FACTOR TS | Authors: | Jiang, Y, Nock, S, Nesper, M, Sprinzl, M, Sigler, P.B. | Deposit date: | 1996-04-16 | Release date: | 1996-11-08 | Last modified: | 2018-03-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and importance of the dimerization domain in elongation factor Ts from Thermus thermophilus. Biochemistry, 35, 1996
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6IX9
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![BU of 6ix9 by Molmil](/molmil-images/mine/6ix9) | The structure of LepI C52A in complex with SAM and leporin C | Descriptor: | (6R,6aS,10S,10aR)-10-methyl-4-phenyl-6-[(1E)-prop-1-en-1-yl]-2,6,6a,7,8,9,10,10a-octahydro-1H-[2]benzopyrano[4,3-c]pyridin-1-one, CHLORIDE ION, GLYCEROL, ... | Authors: | Cai, Y, Ohashi, M, Hai, Y, Tang, Y, Zhou, J. | Deposit date: | 2018-12-09 | Release date: | 2019-07-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.776 Å) | Cite: | Structural basis for stereoselective dehydration and hydrogen-bonding catalysis by the SAM-dependent pericyclase LepI. Nat.Chem., 11, 2019
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6EUC
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![BU of 6euc by Molmil](/molmil-images/mine/6euc) | Reactivating oxime bound to Tc AChE's catalytic gorge. | Descriptor: | 2-[(~{E})-hydroxyiminomethyl]-6-(5-morpholin-4-ylpentyl)pyridin-3-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, ... | Authors: | de la Mora, E, Weik, M, Braiki, A, Mougeot, R, Jean, L, Renard, P.I. | Deposit date: | 2017-10-30 | Release date: | 2018-11-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.21998858 Å) | Cite: | Potent 3-Hydroxy-2-Pyridine Aldoxime Reactivators of Organophosphate-Inhibited Cholinesterases with Predicted Blood-Brain Barrier Penetration. Chemistry, 24, 2018
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6V6Y
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![BU of 6v6y by Molmil](/molmil-images/mine/6v6y) | Crystal Structure of T. thermophilus methylenetetrahydrofolate dehydrogenase (MTHFD) | Descriptor: | Bifunctional protein FolD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Maiello, F, Coelho, C, Gallo, G, Sucharski, F, Hardy, L, Wurtele, M. | Deposit date: | 2019-12-06 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.15201569 Å) | Cite: | Crystal structure of Thermus thermophilus methylenetetrahydrofolate dehydrogenase and determinants of thermostability. Plos One, 15, 2020
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6V4S
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7Z3B
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![BU of 7z3b by Molmil](/molmil-images/mine/7z3b) | Crystal structure of the cupredoxin AcoP from Acidithiobacillus ferrooxidans, reduced form | Descriptor: | ACETATE ION, AcoP, COPPER (I) ION, ... | Authors: | Leone, P, Sciara, G, Ilbert, M. | Deposit date: | 2022-03-02 | Release date: | 2023-09-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Beyond the coupled distortion model: structural analysis of the single domain cupredoxin AcoP, a green mononuclear copper centre with original features. Dalton Trans, 53, 2024
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6V74
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![BU of 6v74 by Molmil](/molmil-images/mine/6v74) | Crystal Structure of Human PKM2 in Complex with L-asparagine | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ASPARAGINE, CHLORIDE ION, ... | Authors: | Nandi, S, Dey, M. | Deposit date: | 2019-12-07 | Release date: | 2020-03-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2. J.Biol.Chem., 295, 2020
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6MTU
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![BU of 6mtu by Molmil](/molmil-images/mine/6mtu) | Crystal structure of human Scribble PDZ1:pMCC complex | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Colorectal mutant cancer protein, ... | Authors: | Caria, S, Stewart, B.Z, Humbert, P.O, Kvansakul, M. | Deposit date: | 2018-10-22 | Release date: | 2019-08-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.141 Å) | Cite: | Structural analysis of phosphorylation-associated interactions of human MCC with Scribble PDZ domains. Febs J., 286, 2019
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7Z3F
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![BU of 7z3f by Molmil](/molmil-images/mine/7z3f) | Crystal structure of the cupredoxin AcoP from Acidithiobacillus ferrooxidans, oxidized form | Descriptor: | ACETATE ION, AcoP, CHLORIDE ION, ... | Authors: | Leone, P, Sciara, G, Ilbert, M. | Deposit date: | 2022-03-02 | Release date: | 2023-09-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Beyond the coupled distortion model: structural analysis of the single domain cupredoxin AcoP, a green mononuclear copper centre with original features. Dalton Trans, 53, 2024
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6EUS
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7Z3G
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![BU of 7z3g by Molmil](/molmil-images/mine/7z3g) | Crystal structure of the cupredoxin AcoP from Acidithiobacillus ferrooxidans, H166A mutant | Descriptor: | AcoP, COPPER (I) ION, GLYCEROL | Authors: | Leone, P, Sciara, G, Ilbert, M. | Deposit date: | 2022-03-02 | Release date: | 2023-09-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Beyond the coupled distortion model: structural analysis of the single domain cupredoxin AcoP, a green mononuclear copper centre with original features. Dalton Trans, 53, 2024
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7Z3I
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![BU of 7z3i by Molmil](/molmil-images/mine/7z3i) | Crystal structure of the cupredoxin AcoP from Acidithiobacillus ferrooxidans, M171A mutant | Descriptor: | ACETATE ION, AcoP, COPPER (II) ION, ... | Authors: | Leone, P, Sciara, G, Ilbert, M. | Deposit date: | 2022-03-02 | Release date: | 2023-09-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Beyond the coupled distortion model: structural analysis of the single domain cupredoxin AcoP, a green mononuclear copper centre with original features. Dalton Trans, 53, 2024
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7SNL
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![BU of 7snl by Molmil](/molmil-images/mine/7snl) | Disulfide stabilized HIV-1 CA hexamer in complex with capsid inhibitor N-(1-(3-(4-chloro-1-methyl-3-(methylsulfonamido)-1H-indazol-7-yl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)acetamide | Descriptor: | CHLORIDE ION, Capsid protein p24, IODIDE ION, ... | Authors: | Bester, S.M, Kvaratskhelia, M. | Deposit date: | 2021-10-28 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Disulfide stabilized HIV-1 CA hexamer in complex with capsid inhibitor N-(1-(3-(4-chloro-1-methyl-3-(methylsulfonamido)-1H-indazol-7-yl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)-2-(3,5-difluorophenyl)ethyl)-2-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)acetamide To Be Published
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6V93
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![BU of 6v93 by Molmil](/molmil-images/mine/6v93) | Structure of DNA Polymerase Zeta/DNA/dNTP Ternary Complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA, ... | Authors: | Malik, R, Kopylov, M, Jain, R, Ubarrextena-Belandia, I, Aggarwal, A.K. | Deposit date: | 2019-12-13 | Release date: | 2020-08-19 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
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6P4U
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![BU of 6p4u by Molmil](/molmil-images/mine/6p4u) | The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module in complex with Mg and AMP | Descriptor: | ACETATE ION, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... | Authors: | Tan, K, Zhou, M, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-05-28 | Release date: | 2019-06-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains. Curr Res Struct Biol, 2, 2020
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6V8J
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![BU of 6v8j by Molmil](/molmil-images/mine/6v8j) | Crystal structure of Ara h 8.0201 | Descriptor: | Ara h 8 allergen isoform, SODIUM ION, SULFATE ION | Authors: | Offermann, L.R, Pote, S, Hurlburt, B.K, McBride, J.K, Chruszcz, M. | Deposit date: | 2019-12-11 | Release date: | 2020-12-16 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of Ara h 8.0201 To Be Published
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