6V6Y
Crystal Structure of T. thermophilus methylenetetrahydrofolate dehydrogenase (MTHFD)
Summary for 6V6Y
| Entry DOI | 10.2210/pdb6v6y/pdb |
| Descriptor | Bifunctional protein FolD, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
| Functional Keywords | amino-acid biosynthesis, histidine biosynthesis, hydrolase, methionine biosynthesis, multifunctional enzyme, nadp, one-carbon metabolism, oxidoreductase, purine biosynthesis |
| Biological source | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
| Total number of polymer chains | 1 |
| Total formula weight | 30984.54 |
| Authors | Maiello, F.,Coelho, C.,Gallo, G.,Sucharski, F.,Hardy, L.,Wurtele, M. (deposition date: 2019-12-06, release date: 2020-05-27, Last modification date: 2023-10-11) |
| Primary citation | Maiello, F.,Gallo, G.,Coelho, C.,Sucharski, F.,Hardy, L.,Wurtele, M. Crystal structure of Thermus thermophilus methylenetetrahydrofolate dehydrogenase and determinants of thermostability. Plos One, 15:e0232959-e0232959, 2020 Cited by PubMed: 32401802DOI: 10.1371/journal.pone.0232959 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.15201566872 Å) |
Structure validation
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