6B71
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![BU of 6b71 by Molmil](/molmil-images/mine/6b71) | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with3-(4-chlorophenyl)-5H,6H-imidazo[2,1-b][1,3]thiazole | Descriptor: | 3-(4-chlorophenyl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | Authors: | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | Deposit date: | 2017-10-03 | Release date: | 2018-10-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 3-(4-chlorophenyl)-5H,6H-imidazo[2,1-b][1,3]thiazole To Be Published
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5EZH
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![BU of 5ezh by Molmil](/molmil-images/mine/5ezh) | Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound 21 at 1.7A resolution | Descriptor: | HTH-type transcriptional regulator EthR, SULFATE ION, ~{N}-[(1-pyridin-2-ylpiperidin-4-yl)methyl]pyrrolidine-1-carboxamide | Authors: | Surade, S, Blaszczyk, M, Nikiforov, P.O, Abell, C, Blundell, T.L. | Deposit date: | 2015-11-26 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters. Org.Biomol.Chem., 14, 2016
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1WUB
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![BU of 1wub by Molmil](/molmil-images/mine/1wub) | Crystal structure of the polyisoprenoid-binding protein, TT1927b, from Thermus thermophilus HB8 | Descriptor: | (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, conserved hypothetical protein TT1927b | Authors: | Handa, N, Idaka, M, Terada, T, Hamana, H, Ishizuka, Y, Park, S.-Y, Tame, J.R.H, Doi-Katayama, Y, Hirota, H, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-12-03 | Release date: | 2004-12-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of a novel polyisoprenoid-binding protein from Thermus thermophilus HB8 Protein Sci., 14, 2005
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5OON
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![BU of 5oon by Molmil](/molmil-images/mine/5oon) | Structure of Undecaprenyl-Pyrophosphate Phosphatase, BacA | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MERCURY (II) ION, ... | Authors: | Huang, C.-Y, Olieric, V, Warshamanage, R, Wang, M, Howe, N, Ghachi, M.E.I, Weichert, D, Kerff, F, Stansfeld, P, Touze, T, Caffrey, M. | Deposit date: | 2017-08-08 | Release date: | 2018-03-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis. Nat Commun, 9, 2018
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5F0F
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![BU of 5f0f by Molmil](/molmil-images/mine/5f0f) | Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound 15 at 1.76A resolution | Descriptor: | 4-[4-(3-oxidanylidene-3-pyrrolidin-1-yl-propyl)piperidin-1-yl]benzenecarbonitrile, HTH-type transcriptional regulator EthR, SULFATE ION | Authors: | Surade, S, Blaszczyk, M, Nikiforov, P.O, Abell, C, Blundell, T.L. | Deposit date: | 2015-11-27 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters. Org.Biomol.Chem., 14, 2016
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2MDZ
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![BU of 2mdz by Molmil](/molmil-images/mine/2mdz) | NMR structure of the Paracoccus denitrificans Z-subunit determined in the presence of ADP | Descriptor: | Uncharacterized protein | Authors: | Serrano, P, Geralt, M, Wuthrich, K, Morales-Rios, E, Zarco-Zavala, M, Garcia-Trejo, J.J, Dutta, S.K, Joint Center for Structural Genomics (JCSG) | Deposit date: | 2013-09-20 | Release date: | 2013-10-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR structure of the putative ATPase regulatory protein YP_916642.1 from Paracoccus denitrificans To be Published
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2M1I
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2M35
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![BU of 2m35 by Molmil](/molmil-images/mine/2m35) | NMR study of k-Ssm1a | Descriptor: | k-Ssm1a | Authors: | King, G.F, Undheim, E.A, Mobli, M, Yang, S, Rong, M, Lai, R. | Deposit date: | 2013-01-09 | Release date: | 2014-01-15 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | NMR study of k-Ssm1a To be Published
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5OPQ
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![BU of 5opq by Molmil](/molmil-images/mine/5opq) | A 3,6-anhydro-D-galactosidase produced by Zobellia galactanivorans. This is an exo-lytic enzyme that hydrolyzes terminal 3,6-anhydro-D-galactose from the non-reducing end of carrageenan oligosaccharides. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6-anhydro-D-galactosidase, ... | Authors: | Ficko-Blean, E, Michel, G, Czjzek, M. | Deposit date: | 2017-08-10 | Release date: | 2017-11-29 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Carrageenan catabolism is encoded by a complex regulon in marine heterotrophic bacteria. Nat Commun, 8, 2017
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5F27
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![BU of 5f27 by Molmil](/molmil-images/mine/5f27) | Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with compound 2 at 1.68A resolution | Descriptor: | HTH-type transcriptional regulator EthR, ~{N}-methyl-1-(4-piperidin-1-ylphenyl)methanamine | Authors: | Surade, S, Blaszczyk, M, Nikiforov, P.O, Abell, C, Blundell, T.L. | Deposit date: | 2015-12-01 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.684 Å) | Cite: | A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters. Org.Biomol.Chem., 14, 2016
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1UH0
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![BU of 1uh0 by Molmil](/molmil-images/mine/1uh0) | Crystal structure of jacalin- Me-alpha-GalNAc complex | Descriptor: | Agglutinin alpha chain, Agglutinin beta-3 chain, methyl 2-acetamido-2-deoxy-alpha-D-galactopyranoside | Authors: | Jeyaprakash, A.A, Katiyar, S, Swaminathan, C.P, Sekar, K, Surolia, A, Vijayan, M. | Deposit date: | 2003-06-23 | Release date: | 2003-09-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis of the Carbohydrate Specificities of Jacalin: An X-ray and Modeling Study J.MOL.BIOL., 332, 2003
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6AQT
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![BU of 6aqt by Molmil](/molmil-images/mine/6aqt) | Crystal Structure of Z-DNA with 6-fold Twinning_Z3A | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3') | Authors: | Luo, Z, Dauter, Z, Gilski, M. | Deposit date: | 2017-08-21 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Four highly pseudosymmetric and/or twinned structures of d(CGCGCG)2 extend the repertoire of crystal structures of Z-DNA. Acta Crystallogr D Struct Biol, 73, 2017
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2M39
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6AQW
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![BU of 6aqw by Molmil](/molmil-images/mine/6aqw) | Crystal Structure of Z-DNA with 6-fold Twinning_Z4A | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3') | Authors: | Luo, Z, Dauter, Z, Gilski, M. | Deposit date: | 2017-08-21 | Release date: | 2017-08-30 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Four highly pseudosymmetric and/or twinned structures of d(CGCGCG)2 extend the repertoire of crystal structures of Z-DNA. Acta Crystallogr D Struct Biol, 73, 2017
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2M3F
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![BU of 2m3f by Molmil](/molmil-images/mine/2m3f) | NMR structure of Rsa1p238-259 from S. Cerevisiae | Descriptor: | Ribosome assembly 1 protein | Authors: | Quinternet, M, Manival, X. | Deposit date: | 2013-01-17 | Release date: | 2013-11-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Characterization of the interaction between protein Snu13p/15.5K and the Rsa1p/NUFIP factor and demonstration of its functional importance for snoRNP assembly. Nucleic Acids Res., 42, 2014
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6AR6
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6IY2
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![BU of 6iy2 by Molmil](/molmil-images/mine/6iy2) | Structure of Snf2-MMTV-A nucleosome complex at shl2 in ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (147-MER), DNA (167-MER), ... | Authors: | Li, M, Xia, X, Liu, X, Li, X, Chen, Z. | Deposit date: | 2018-12-12 | Release date: | 2019-04-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Mechanism of DNA translocation underlying chromatin remodelling by Snf2. Nature, 567, 2019
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2M4M
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![BU of 2m4m by Molmil](/molmil-images/mine/2m4m) | Solution structure of the RRM domain of the hypothetical protein CAGL0M09691g from Candida glabrata | Descriptor: | hypothetical protein | Authors: | Harris, R, Hillerich, B, Ahmed, M, Bonanno, J.B, Chamala, S, Evans, B, Lafleur, J, Hammonds, J, Washington, E, Stead, M, Love, J, Attonito, J, Patel, H, Seidel, R.D, Chook, Y.M, Rout, M.P, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) | Deposit date: | 2013-02-07 | Release date: | 2013-02-27 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the RRM domain of the hypothetical protein CAGL0M09691g from Candida glabrata To be Published
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6AUD
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![BU of 6aud by Molmil](/molmil-images/mine/6aud) | PI3K-gamma K802T in complex with Cpd 8 10-((1-(tert-butyl)piperidin-4-yl)sulfinyl)-2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine | Descriptor: | 10-[(S)-(1-tert-butylpiperidin-4-yl)sulfinyl]-2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Authors: | Murray, J.M, Ultsch, M. | Deposit date: | 2017-08-31 | Release date: | 2017-11-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.015 Å) | Cite: | Design of Selective Benzoxazepin PI3K delta Inhibitors Through Control of Dihedral Angles. ACS Med Chem Lett, 8, 2017
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6AVW
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6AWZ
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![BU of 6awz by Molmil](/molmil-images/mine/6awz) | Structure of PR-10 allergen from peanut (Ara h 8.01). | Descriptor: | Ara h 8 allergen, SODIUM ION, TETRAETHYLENE GLYCOL | Authors: | Offermann, L.R, Majorek, K, McBride, J, Hurlburt, B.K, Maleki, S.J, Pote, S.S, Chruszcz, M. | Deposit date: | 2017-09-06 | Release date: | 2018-09-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of PR-10 Allergen Ara h 8.01. To Be Published
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2MH5
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![BU of 2mh5 by Molmil](/molmil-images/mine/2mh5) | Structure and NMR assignments of lantibiotic NAI-107 in DPC micelles | Descriptor: | Lantibiotic 107891, dodecyl 2-(trimethylammonio)ethyl phosphate | Authors: | Munch, D, Muller, A, Schneider, T, Kohl, B, Wenzel, M, Bandow, J, Maffioli, S, Sosio, M, Donadio, S, Wimmer, R, Sahl, H. | Deposit date: | 2013-11-18 | Release date: | 2014-03-05 | Last modified: | 2024-07-10 | Method: | SOLUTION NMR | Cite: | The Lantibiotic NAI-107 Binds to Bactoprenol-bound Cell Wall Precursors and Impairs Membrane Functions. J.Biol.Chem., 289, 2014
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6AYE
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![BU of 6aye by Molmil](/molmil-images/mine/6aye) | Human apo-TRPML3 channel at pH 7.4 | Descriptor: | Mucolipin-3 | Authors: | Zhou, X, Li, M, Su, D, Jia, Q, Li, H, Li, X, Yang, J. | Deposit date: | 2017-09-08 | Release date: | 2017-11-08 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.06 Å) | Cite: | Cryo-EM structures of the human endolysosomal TRPML3 channel in three distinct states. Nat. Struct. Mol. Biol., 24, 2017
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6B62
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![BU of 6b62 by Molmil](/molmil-images/mine/6b62) | IMPase (AF2372) with 400 mM Glutamate | Descriptor: | Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B6L
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![BU of 6b6l by Molmil](/molmil-images/mine/6b6l) | The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 | Descriptor: | 1,2-ETHANEDIOL, FORMIC ACID, Glycosyl hydrolase family 2, ... | Authors: | Tan, K, Joachimiak, G, Nocek, B, Enddres, M, Babnigg, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2017-10-02 | Release date: | 2017-10-11 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 To Be Published
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