6B71

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with3-(4-chlorophenyl)-5H,6H-imidazo[2,1-b][1,3]thiazole

Summary for 6B71

• Entry DOI: 10.2210/pdb6b71/pdb
• Related: 5CXQ
• Descriptor: Purine nucleoside phosphorylase, DIMETHYL SULFOXIDE, 3-(4-chlorophenyl)-5,6-dihydroimidazo[2,1-b][1,3]thiazole, ... (4 entities in total)
• Functional Keywords: purine nucleoside phosphorylase, transferase, transferase-inhibitor complex, transferase/inhibitor
• Biological source: Schistosoma mansoni (Blood fluke)
• Total number of polymer chains: 1
• Total formula weight: 32062.86

Authors

Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G. (deposition date: 2017-10-03, release date: 2018-10-10, Last modification date: 2023-10-04)

• Primary citation: Faheem, M.,Neto, J.B.,Collins, P.,Pearce, N.M.,Valadares, N.F.,Bird, L.,Pereira, H.M.,Delft, F.V.,Barbosa, J.A.R.G.; Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 3-(4-chlorophenyl)-5H,6H-imidazo[2,1-b][1,3]thiazole; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.52 Å)