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PDB: 264 results

4IHJ
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BU of 4ihj by Molmil
Crystal structure of tubulin-stathmin-TTL-ADP complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Prota, A.E, Magiera, M.M, Kuijpers, M, Bargsten, K, Frey, D, Wieser, M, Jaussi, R, Hoogenraad, C.C, Kammerer, R.A, Janke, C, Steinmetz, M.O.
Deposit date:2012-12-18
Release date:2013-02-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tubulin tyrosination by tubulin tyrosine ligase.
J.Cell Biol., 200, 2013
4IIJ
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BU of 4iij by Molmil
Crystal structure of tubulin-stathmin-TTL-apo complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Prota, A.E, Magiera, M.M, Kuijpers, M, Bargsten, K, Frey, D, Wieser, M, Jaussi, R, Hoogenraad, C.C, Kammerer, R.A, Janke, C, Steinmetz, M.O.
Deposit date:2012-12-20
Release date:2013-01-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of tubulin tyrosination by tubulin tyrosine ligase.
J.Cell Biol., 200, 2013
4IQA
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BU of 4iqa by Molmil
Crystal Structure Analysis of the E228L Mutant of Human CLIC1
Descriptor: Chloride intracellular channel protein 1
Authors:Cross, M.O, Achilonu, I.A, Fernandes, M.A, Fanucchi, S, Dirr, H.W.
Deposit date:2013-01-11
Release date:2013-02-20
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Crystal Structure Analysis of the E228L Mutant of Human CLIC1
TO BE PUBLISHED
1FQ8
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BU of 1fq8 by Molmil
X-RAY STRUCTURE OF DIFLUOROSTATINE INHIBITOR CP81,198 BOUND TO SACCHAROPEPSIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(2S)-1-[[(2S)-1-[[(2S,3R)-1-cyclohexyl-4,4-difluoro-3-hydroxy-5-(methylamino)-5-oxo-pentan-2-yl]amino]-1-oxo-hexan-2 -yl]amino]-1-oxo-3-phenyl-propan-2-yl]morpholine-4-carboxamide, SACCHAROPEPSIN, ...
Authors:Cronin, N.B, Badasso, M.O, Tickle, I.J, Dreyer, T, Hoover, D.J, Rosati, R.L, Humblet, C.C, Lunney, E.A, Cooper, J.B.
Deposit date:2000-09-04
Release date:2000-09-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J.Mol.Biol., 303, 2000
1FOQ
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BU of 1foq by Molmil
PENTAMERIC MODEL OF THE BACTERIOPHAGE PHI29 PROHEAD RNA
Descriptor: BACTERIOPHAGE PHI29 PROHEAD RNA
Authors:Simpson, A.A, Tao, Y, Leiman, P.G, Badasso, M.O, He, Y, Jardine, P.J, Olson, N.H, Morais, M.C, Grimes, S, Anderson, D.L, Baker, T.S, Rossmann, M.G.
Deposit date:2000-08-28
Release date:2000-12-22
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (20 Å)
Cite:Structure of the bacteriophage phi29 DNA packaging motor.
Nature, 408, 2000
1FQ6
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BU of 1fq6 by Molmil
X-RAY STRUCTURE OF GLYCOL INHIBITOR PD-133,450 BOUND TO SACCHAROPEPSIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(1S)-2-{[(2S,3R,4S)-1-cyclohexyl-3,4-dihydroxy-6-methylheptan-2-yl]amino}-1-(ethylsulfanyl)-2-oxoethyl]-Nalpha-(morp holin-4-ylsulfonyl)-L-phenylalaninamide, SACCHAROPEPSIN, ...
Authors:Cronin, N.B, Badasso, M.O, Tickle, I.J, Dreyer, T, Hoover, D.J, Rosati, R.L, Humblet, C.C, Lunney, E.A, Cooper, J.B.
Deposit date:2000-09-03
Release date:2000-09-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J.Mol.Biol., 303, 2000
1FQ7
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BU of 1fq7 by Molmil
X-RAY STRUCTURE OF INHIBITOR CP-72,647 BOUND TO SACCHAROPEPSIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-(tert-butoxycarbonyl)-L-phenylalanyl-N-[(2S,3S,5R)-1-cyclohexyl-3-hydroxy-7-methyl-5-(methylcarbamoyl)octan-2-yl]-L-histidinamide, SACCHAROPEPSIN, ...
Authors:Cronin, N.B, Badasso, M.O, Tickle, I.J, Dreyer, T, Hoover, D.J, Rosati, R.L, Humblet, C.C, Lunney, E.A, Cooper, J.B.
Deposit date:2000-09-04
Release date:2000-09-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J.Mol.Biol., 303, 2000
1GN6
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BU of 1gn6 by Molmil
G152A mutant of Mycobacterium tuberculosis iron-superoxide dismutase.
Descriptor: FE (III) ION, SUPEROXIDE DISMUTASE
Authors:Bunting, K.A, Cooper, J.B, Saward, S, Erskine, P.T, Badasso, M.O, Wood, S.P, Zhang, Y, Young, D.B.
Deposit date:2001-10-03
Release date:2001-10-05
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:X-Ray Structure Analysis of an Engineered Fe-Superoxide Dismutase Gly-Ala Mutant with Significantly Reduced Stability to Denaturant
FEBS Lett., 387, 1996
1GN4
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BU of 1gn4 by Molmil
H145E mutant of Mycobacterium tuberculosis iron-superoxide dismutase.
Descriptor: MANGANESE (II) ION, SUPEROXIDE DISMUTASE
Authors:Bunting, K.A, Cooper, J.B, Badasso, M.O, Tickle, I.J, Newton, M, Wood, S.P, Zhang, Y, Young, D.B.
Deposit date:2001-10-02
Release date:2001-10-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants
Eur.J.Biochem., 251, 1998
1GN3
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BU of 1gn3 by Molmil
H145Q mutant of Mycobacterium tuberculosis iron-superoxide dismutase.
Descriptor: FE (III) ION, SUPEROXIDE DISMUTASE
Authors:Bunting, K.A, Cooper, J.B, Badasso, M.O, Tickle, I.J, Newton, M, Wood, S.P, Zhang, Y, Young, D.B.
Deposit date:2001-10-02
Release date:2001-10-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants.
Eur.J.Biochem., 251, 1998
1FQ4
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BU of 1fq4 by Molmil
CRYSTAL STRUCTURE OF A COMPLEX BETWEEN HYDROXYETHYLENE INHIBITOR CP-108,420 AND YEAST ASPARTIC PROTEINASE A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(2R)-1-{[(2S,3R,5R)-1-cyclohexyl-3-hydroxy-5-{[2-(morpholin-4-yl)ethyl]carbamoyl}oct-7-yn-2-yl]amino}-3-(methylsulfa nyl)-1-oxopropan-2-yl]-1H-benzimidazole-2-carboxamide, SACCHAROPEPSIN, ...
Authors:Cronin, N.B, Badasso, M.O, Tickle, I.J, Dreyer, T, Hoover, D.J, Rosati, R.L, Humblet, C.C, Lunney, E.A, Cooper, J.B.
Deposit date:2000-09-03
Release date:2000-09-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J.Mol.Biol., 303, 2000
1FQ5
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BU of 1fq5 by Molmil
X-ray structure of a cyclic statine inhibitor PD-129,541 bound to yeast proteinase A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-[(5S,9S,10S,13S)-9-hydroxy-5,10-bis(2-methylpropyl)-4,7,12,16-tetraoxo-3,6,11,17-tetraazabicyclo[17.3.1]tricosa-1(23),19,21-trien-13-yl]-3-(naphthalen-1-yl)-2-(naphthalen-1-ylmethyl)propanamide, SACCHAROPEPSIN, ...
Authors:Cronin, N.B, Badasso, M.O, Tickle, I.J, Dreyer, T, Hoover, D.J, Rosati, R.L, Humblet, C.C, Lunney, E.A, Cooper, J.B.
Deposit date:2000-09-03
Release date:2000-09-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
J.Mol.Biol., 303, 2000
1SD0
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BU of 1sd0 by Molmil
Structure of arginine kinase C271A mutant
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ARGININE, Arginine kinase, ...
Authors:Gattis, J.L, Ruben, E, Fenley, M.O, Ellington, W.R, Chapman, M.S.
Deposit date:2004-02-12
Release date:2004-07-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The active site cysteine of arginine kinase: structural and functional analysis of partially active mutants
Biochemistry, 43, 2004
5JVD
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BU of 5jvd by Molmil
Tubulin-TUB092 complex
Descriptor: (2E)-3-(3-hydroxy-4-methoxyphenyl)-1-(7-methoxy-2H-1,3-benzodioxol-5-yl)-2-methylprop-2-en-1-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Canela, M.-D, Noppen, S, Bueno, O, Prota, A.E, Bargsten, K, Saez-Calvo, G, Jimeno, M.-L, Benkheil, M, Ribatti, D, Velazquez, S, Camarasa, M.-J, Diaz, J.F, Steinmetz, M.O, Priego, E.-M, Perez-Perez, M.-J, Liekens, S.
Deposit date:2016-05-11
Release date:2016-06-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Antivascular and antitumor properties of the tubulin-binding chalcone TUB091.
Oncotarget, 8, 2017
2LTI
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BU of 2lti by Molmil
Structure of lasso peptide Astexin1
Descriptor: ASTEXIN1
Authors:Maksimov, M.O, Link, A.J.
Deposit date:2012-05-25
Release date:2012-09-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Precursor-centric genome-mining approach for lasso peptide discovery.
Proc.Natl.Acad.Sci.USA, 109, 2012
5LB7
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BU of 5lb7 by Molmil
Complex structure between p60N/p80C katanin and a peptide derived from ASPM
Descriptor: Abnormal spindle-like microcephaly-associated protein homolog, Katanin p60 ATPase-containing subunit A1, Katanin p80 WD40 repeat-containing subunit B1
Authors:Rezabkova, L, Capitani, G, Kammerer, R.A, Steinmetz, M.O.
Deposit date:2016-06-15
Release date:2017-04-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex.
Nat. Cell Biol., 19, 2017
2M8F
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BU of 2m8f by Molmil
Structure of lasso peptide astexin3
Descriptor: astexin3
Authors:Maksimov, M.O, Link, A.
Deposit date:2013-05-18
Release date:2013-07-31
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Discovery and characterization of an isopeptidase that linearizes lasso peptides.
J.Am.Chem.Soc., 135, 2013
2N68
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BU of 2n68 by Molmil
Solution study of Astexin1
Descriptor: astexin1
Authors:Link, A.J, Maksimov, M.O.
Deposit date:2015-08-13
Release date:2015-11-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Construction of Lasso Peptide Fusion Proteins.
Acs Chem.Biol., 11, 2016
5LA6
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BU of 5la6 by Molmil
Tubulin-pironetin complex
Descriptor: CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Prota, A.E, Setter, J, Waight, A.B, Bargsten, K, Murga, J, Diaz, J.F, Steinmetz, M.O.
Deposit date:2016-06-13
Release date:2016-07-20
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pironetin Binds Covalently to alpha Cys316 and Perturbs a Major Loop and Helix of alpha-Tubulin to Inhibit Microtubule Formation.
J.Mol.Biol., 428, 2016
5LZN
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BU of 5lzn by Molmil
-TIP microtubule-binding domain
Descriptor: Calmodulin-regulated spectrin-associated protein 3
Authors:Stangier, M.M, Steinmetz, M.O.
Deposit date:2016-09-30
Release date:2017-10-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A structural model for microtubule minus-end recognition and protection by CAMSAP proteins.
Nat. Struct. Mol. Biol., 24, 2017
1RLG
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BU of 1rlg by Molmil
Molecular basis of Box C/D RNA-protein interaction: co-crystal structure of the Archaeal sRNP intiation complex
Descriptor: 25-MER, 50S ribosomal protein L7Ae
Authors:Moore, T, Zhang, Y, Fenley, M.O, Li, H.
Deposit date:2003-11-25
Release date:2004-06-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular Basis of Box C/D RNA-Protein Interactions; Cocrystal Structure of Archaeal L7Ae and a Box C/D RNA.
STRUCTURE, 12, 2004
5JH7
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BU of 5jh7 by Molmil
Tubulin-Eribulin complex
Descriptor: (1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,33R,35R,36S)-20-[(2S)-3-amino-2-hydroxypropyl]-21-methoxy-14-methyl-8,15-dimethylidene-2,19,30,34,37,39,40,41-octaoxanonacyclo[24.9.2.1~3,32~.1~3,33~.1~6,9~.1~12,16~.0~18,22~.0~29,36~.0~31,35~]hentetracontan-24-one (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Doodhi, H, Prota, A.E, Rodriguez-Garcia, R, Xiao, H, Custar, D.W, Bargsten, K, Katrukha, E.A, Hilbert, M, Hua, S, Jiang, K, Grigoriev, I, Yang, C.-P.H, Cox, D, Band Horwitz, S, Kapitein, L.C, Akhmanova, A, Steinmetz, M.O.
Deposit date:2016-04-20
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes.
Curr.Biol., 26, 2016
1ROV
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BU of 1rov by Molmil
Lipoxygenase-3 Treated with Cumene Hydroperoxide
Descriptor: FE (III) ION, Seed lipoxygenase-3
Authors:Vahedi-Faridi, A, Brault, P.A, Shah, P, Kim, Y.W, Dunham, W.R, Funk, M.O.
Deposit date:2003-12-02
Release date:2004-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interaction between non-heme iron of lipoxygenases and cumene hydroperoxide: basis for enzyme activation, inactivation, and inhibition
J.Am.Chem.Soc., 126, 2004
5LOV
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BU of 5lov by Molmil
DZ-2384 tubulin complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, DZ 2384, ...
Authors:Prota, A.E, Steinmetz, M.O, Shore, G.C, Brouhard, G, Roulston, A.
Deposit date:2016-08-10
Release date:2016-11-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Sci Transl Med, 8, 2016
2N6U
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BU of 2n6u by Molmil
Solution study of Astexin2-dC4
Descriptor: Astexin2-dC4
Authors:Link, A, Maksimov, M.O.
Deposit date:2015-08-28
Release date:2015-11-11
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase.
J.Biol.Chem., 290, 2015

221371

数据于2024-06-19公开中

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