6S0Q

Structure of the A2A adenosine receptor determined at SwissFEL using native-SAD at 4.57 keV from 50,000 diffraction patterns

Summary for 6S0Q

• Entry DOI: 10.2210/pdb6s0q/pdb
• Related: 6S0L
• Descriptor: Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, OLEIC ACID, ... (6 entities in total)
• Functional Keywords: native-sad, serial femtosecond crystallography, sfx, swissfel, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 52897.43

Authors

Nass, K.,Cheng, R.,Vera, L.,Mozzanica, A.,Redford, S.,Ozerov, D.,Basu, S.,James, D.,Knopp, G.,Cirelli, C.,Martiel, I.,Casadei, C.,Weinert, T.,Nogly, P.,Skopintsev, P.,Usov, I.,Leonarski, F.,Geng, T.,Rappas, M.,Dore, A.S.,Cooke, R.,Nasrollahi Shirazi, S.,Dworkowski, F.,Sharpe, M.,Olieric, N.,Steinmetz, M.O.,Schertler, G.,Abela, R.,Patthey, L.,Schmitt, B.,Hennig, M.,Standfuss, J.,Wang, M.,Milne, J.C. (deposition date: 2019-06-18, release date: 2020-07-15, Last modification date: 2023-12-13)

• Primary citation: Nass, K.,Cheng, R.,Vera, L.,Mozzanica, A.,Redford, S.,Ozerov, D.,Basu, S.,James, D.,Knopp, G.,Cirelli, C.,Martiel, I.,Casadei, C.,Weinert, T.,Nogly, P.,Skopintsev, P.,Usov, I.,Leonarski, F.,Geng, T.,Rappas, M.,Dore, A.S.,Cooke, R.,Nasrollahi Shirazi, S.,Dworkowski, F.,Sharpe, M.,Olieric, N.,Bacellar, C.,Bohinc, R.,Steinmetz, M.O.,Schertler, G.,Abela, R.,Patthey, L.,Schmitt, B.,Hennig, M.,Standfuss, J.,Wang, M.,Milne, C.J.; Advances in long-wavelength native phasing at X-ray free-electron lasers.; Iucrj, 7:965-975, 2020; PubMed: 33209311; DOI: 10.1107/S2052252520011379

Experimental method

X-RAY DIFFRACTION (2.65 Å)